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    East Stroudsburg, PA Medical Office Space for Lease

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    Stroudsburg, PA Marshalls Creek, PA Tannersville, PA Mount Bethel, PA Scotrun, PA Bangor, PA Pen Argyl, PA Saylorsburg, PA
    8 properties
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    Freestanding Office Building
    Updated: May 14
    Freestanding Office Building

    5226 Milford Road, East Stroudsburg, PA 18302

    $2,995/Mo
    1,855 sqft
    Freestanding commercial building for lease with visibility to more than 19,000 vehicles per day
    Includes reception/waiting area with natural stone fireplace plus open office area and restroom
    Two glass‑walled conference rooms and three private offices
    Outside features two large signs and 16 parking spaces
    Utilities: well water and public sewer; heating includes electric and propane
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    East Stroudsburg Professional Office Suite
    Updated: Oct 30, 2025
    East Stroudsburg Professional Office Suite

    507 Seven Bridge Road, East Stroudsburg, PA 18301

    $3,250/Mo
    2,165 sqft
    Ideal location on busy Route 209 with high traffic count (18,000+ daily) for excellent visibility and convenience.
    Professional and Medical Office Building suitable for office or medical use.
    Convenient access to I‑80.
    ADA accessibility and elevator enhance customer/patient experience.
    Interior courtyard provides an elevated business image.
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    East Stroudsburg Office Space Available
    East Stroudsburg Office Space Available

    507 Seven Bridge Road, East Stroudsburg, PA 18301

    $675/Mo
    450 sqft

    Professional/Medical office space for rent in East Stroudsburg, PA.

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    Medical Office Suite
    Medical Office Suite

    4545 Milford Road, East Stroudsburg, PA 18302

    $15 SF/Yr
    4,000 sqft

    Former urgent care space with a medical-ready floorplan, pylon and overhead signage, and ample parking near a high-traffic corridor.

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    Partitionable Medical Office/Retail Space
    Partitionable Medical Office/Retail Space

    106 Shawnee Square Dr, First Floor, East Stroudsburg, PA 18301

    $12/Mo
    4,610 sqft

    First-floor space can be leased as one unit or partitioned into two, with ADA-compliant layout and on-site parking.

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    East Stroudsburg Office/Medical Space
    East Stroudsburg Office/Medical Space

    507 Seven Bridges Road, East Stroudsburg, PA 18301

    $1,275/Mo
    651 sqft

    Professional office building near I-80 on Route 209.

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    Freestanding Office Building
    Freestanding Office Building

    5226 Milford Road, East Stroudsburg, PA 18302

    $2,800/Mo

    Freestanding office building with reception, multiple offices and conference rooms, plus 16 parking spaces and outdoor signage.

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    COMMERCIAL - East Stroudsburg, PA
    COMMERCIAL - East Stroudsburg, PA

    106 Shawnee Sq Dr, Unit FIRST, East Stroudsburg, PA 18301

    $12 SF/Yr

    Adaptable 4,610 SF space in high-traffic Shawnee Square.

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    Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 8 Active listings in East Stroudsburg, PA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Ground-Level Retail and Office Space
    Ground-Level Retail and Office Space

    3 Broadway, Bangor, PA 18013

    $10 SF/Yr
    1,600 sqft

    Ground-level suite with large display windows, ADA restroom, rear office/storage, and central HVAC for retail or professional use.

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    Medical Office Suite
    Medical Office Suite

    107 N 7th Street, Stroudsburg, PA 18360

    $2,950/Mo

    Office suite with two bathrooms and kitchenette, plus attic storage in eight separate rooms across two floors.

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    Updated Medical Office Suites
    Updated Medical Office Suites

    225 Erdman Street, Bangor, PA 18013

    $1,200/Mo

    Single-story medical office suites offer exams rooms and shared common areas with all utilities included.

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    Handicap Accessible Medical Office
    Handicap Accessible Medical Office

    117 Broad Street, Stroudsburg, PA 18360

    $400/Mo

    Shared psychology building with off-street back parking and handicap accessibility for client-facing office use.

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    Similar Spaces for Sale in East Stroudsburg, PA

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Medical Office Building with Parking
    Medical Office Building with Parking

    371 E Brown Street, East Stroudsburg, PA 18301

    $599,000
    5,484 sqft 1.07 AC lot

    Multi-unit medical and office building offers three suites, ample parking, and strong access for professional users.

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    Multi-Unit Medical Office Building
    Multi-Unit Medical Office Building

    371 E Brown Street, East Stroudsburg, PA 18301

    $599,000
    5,484 sqft 1.07 AC lot

    Three-unit medical office building with ample parking and strong visibility in the Pocono medical district.

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    Retail and Medical Office Building
    Retail and Medical Office Building

    5159 Milford Rd, East Stroudsburg, PA 18301

    Contact for pricing
    1,334 sqft

    Commercial building on Route 209 with 110+ feet of road frontage and 7 rooms with hardwood floors.

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    Second-Floor Medical Office Suite
    Second-Floor Medical Office Suite

    507 Seven Bridge Rd, East Stroudsburg, PA 18301

    Contact for pricing

    ADA accessible second-floor suite with elevator, courtyard, and on-site parking near I-80 for medical or office use.

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    Second-Floor Medical Office Suite
    Second-Floor Medical Office Suite

    500 Vna Road, Ste #201, East Stroudsburg, PA 18301

    Contact for pricing
    2,500 sqft

    Elevator-served second-floor suite offers open layout, one private office, ADA restrooms, and a kitchenette.

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    Medical Office Suite with Labs
    Medical Office Suite with Labs

    175 E Brown St Suite 112, East Stroudsburg, PA 18301

    Contact for pricing
    800 sqft

    Office suite in the Pocono Medical Buildings with exam rooms, labs, reception, waiting area, and on-site parking.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Pad Site for Lease
    Prime Pad Site for Lease

    9 Old State Rd, Belmont, NH 03220

    Contact for pricing

    Highly visible 1.74 acre pad site in Belmont, NH.

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    Commercial Land Parcel with Utilities
    Commercial Land Parcel with Utilities

    2585 Maple Lane, Pittsburgh, PA 15241

    $50,000/Mo

    Level, fully serviced commercial parcel with approvals in place and signage permitted up to 20 sq ft.

    View details
    Prime Lexington Outlot Opportunity
    Prime Lexington Outlot Opportunity

    3330 Partner Place, Lexington, KY 40503

    Contact for pricing

    Outlot for ground lease or build-to-suit in South Lexington.

    View details
    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    View details

    East Stroudsburg, PA Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in East Stroudsburg, PA with 8 listings featured on our commercial real estate exchange. The current inventory includes 9,121 square feet of properties with an estimated lease value of $93.88 SF/Yr.

    Estimated lease rates for Medical Office Space in East Stroudsburg, PA begin at $15 SF/Yr, with an average of $18.78 SF/Yr and extend to $23.50 SF/Yr.
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    Most Searched ZIP Codes in East Stroudsburg, PA

    • 18301
    • 18302

    Featured East Stroudsburg Real Estate Agencies

    Realmo connects you with licensed East Stroudsburg CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Smart Way America Realty
    696 Seven Bridge rd East Stroudsburg, PA 18301
    Phone: 15703715173
    www.smartwayamerica.com
    SER Commercial Real Estate, LLC
    215 Independence Rd East Stroudsburg, PA
    Phone: 15704317400
    Iron Valley Real Estate Pocono
    46 South Crystal Street East Stroudsburg, PA 18301
    Phone: 15704240926
    www.ironvalleyrealestatepocono.com

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