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    East Stroudsburg, PA

    East Stroudsburg, PA Commercial Real Estate for Lease

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    39 properties
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    Medical Office Space with Private Offices
    Updated: Jul 22
    Medical Office Space with Private Offices

    526 Independence Road, East Stroudsburg, PA 18301

    $18 SF/Yr
    2,762 sqft 0.67 AC lot
    Nine private offices within a medical or professional office suite
    ADA‑accessible configuration
    Reception and waiting area, conference room, and breakroom
    Three restrooms
    Just off I‑80 near numerous medical practices
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    Creative Space with Exposed Beams
    Updated: Oct 13
    Creative Space with Exposed Beams

    103 Five Star Lane, East Stroudsburg, PA 18301

    $950/Mo
    940 sqft 3.00 AC lot
    940‑square‑foot creative space in a renovated historic bank barn
    Original beams remain visible throughout the interior
    ADA access
    Located within the Keystone Innovation Zone, which offers tax credits to for‑profit companies
    Owner willing to complete updates for qualified tenants
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    Remodeled Medical Office Space
    Remodeled Medical Office Space

    296 E Brown Street, East Stroudsburg, PA 18301

    $3,000/Mo
    1,900 sqft 0.61 AC lot

    ADA-compliant healthcare suite with private exam rooms, reception, waiting, and office areas for efficient patient service.

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    Class A Medical Office Space
    Class A Medical Office Space

    526 Independence Rd, East Stroudsburg, PA 18301

    $18 SF/Yr
    2,762 sqft

    Professional office suite with private rooms, patient areas, and convenient access near complementary medical practices.

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    Remodeled Medical Office Space
    Remodeled Medical Office Space

    296 E Brown Street, East Stroudsburg, PA 18301

    $3,000/Mo
    1,900 sqft 0.61 AC lot

    ADA-compliant healthcare suite with patient reception, private exam rooms, and a separate office.

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    First-Floor Office Unit
    First-Floor Office Unit

    315 Dartmouth Dr., Unit #1, East Stroudsburg, PA 18301

    $2,995/Mo
    2,277 sqft 1.97 AC lot

    Office space includes a kitchen and two ADA restrooms.

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    Specialty Commercial Space
    Specialty Commercial Space

    764 Milford Road, East Stroudsburg, PA 18301

    $1,600/Mo
    800 sqft 0.50 AC lot

    Commercial space along Milford Road with rear parking, electric heat, and public water and sewer.

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    Renovated Mixed-Use Barn Space
    Renovated Mixed-Use Barn Space

    201-103 Five Star Lane, East Stroudsburg, PA 18301

    $950/Mo
    940 sqft

    The interior retains exposed original beams and has ADA access for a range of commercial layouts.

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    Second-Floor Office Units
    Second-Floor Office Units

    78 S Courtland Street, East Stroudsburg, PA 18301

    $1,850/Mo
    2,500 sqft 0.06 AC lot

    Bright office accommodation with private offices and a reception area in a brick building.

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    Office Units with Waiting Area
    Office Units with Waiting Area

    33 Dansbury Terrace, East Stroudsburg, PA 18301

    $1,500/Mo
    15,000 sqft 0.12 AC lot

    Lease opportunity with two rooms, a kitchenette, front reception area, and allocated off-street parking.

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    Remodeled Medical Office Space
    Remodeled Medical Office Space

    C-296 E Brown St, East Stroudsburg, PA 18301

    $3,000/Mo
    1,900 sqft

    ADA-compliant medical layout with reception, waiting, exam, and private office areas supports efficient practice operations.

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    Inline Retail Space
    Inline Retail Space

    4543 Milford Road, East Stroudsburg, PA 18302

    $20 SF/Yr
    103,661 sqft 12.58 AC lot

    In-line storefront within a leased shopping center, offering central air and public water and sewer service.

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    First-Floor Flex Space
    First-Floor Flex Space

    3215 N 5th Street, East Stroudsburg, PA 18301

    $2,500/Mo
    1,500 sqft 160.40 AC lot

    Open commercial layout with road frontage, accessible ramp entry, parking, and signage options for tenant branding.

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    Retail Space with Rear Parking
    Retail Space with Rear Parking

    764 Milford Rd, East Stroudsburg, PA 18301

    $1,600/Mo
    800 sqft

    Retail space with rear parking and frontage along Milford Road in East Stroudsburg Borough.

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    Medical Office Suite with Elevator
    Medical Office Suite with Elevator

    507 Seven Bridge Road, East Stroudsburg, PA 18301

    $3,250/Mo
    2,165 sqft 5.12 AC lot

    Office space offers ADA access, an interior courtyard, elevator service, and on-site parking for visitors and staff.

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    Medical Office Suite
    Medical Office Suite

    507 Seven Bridge Road, East Stroudsburg, PA 18301

    $675/Mo
    450 sqft 5.12 AC lot

    Professional office setting with elevator access, ADA features, and on-site parking for patients, clients, and staff.

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    Inline Retail Storefront
    Inline Retail Storefront

    60-4543 Milford Rd, East Stroudsburg, PA 18301

    $20 SF/Yr
    1,400 sqft

    Retail space in a shopping center serving established anchor and specialty operators.

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    Freestanding Drug Store with Drive-Through
    Freestanding Drug Store with Drive-Through

    4555 Milford Road, East Stroudsburg, PA 18302

    $24 SF/Yr
    102,600 sqft 12.58 AC lot

    Large retail building with subdivision flexibility, monument-scale pylon signage, and a customer drive-through.

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    Two-Room Office Suite
    Two-Room Office Suite

    33 Dansbury Ter, East Stroudsburg, PA 18301

    $1,500/Mo
    1,200 sqft

    Lease space includes a kitchenette, waiting area, and allocated off-street parking.

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    Drive-Through Bank Branch
    Drive-Through Bank Branch

    209 Skyline Drive, East Stroudsburg, PA 18301

    $21 SF/Yr
    0.59 AC lot

    Brick-built commercial space with central air, public utilities, parking, and a three-lane drive-through.

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    Office Suites Across from Hospital
    Office Suites Across from Hospital

    Ste2-239 E Brown St, East Stroudsburg, PA 18301

    $3,413/Mo
    2,100 sqft

    Multiple office suites are available, with rent covering electric, water, sewer, heat, and CAM.

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    Commercial Land with Curb Cut
    Commercial Land with Curb Cut

    4540 Milford Road, East Stroudsburg, PA 18302

    $110,000/Mo
    2,500 sqft 12.59 AC lot

    Pad site positioned at the front of The Shoppes at Marshalls Creek with an existing access point for ingress and egress.

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    Move-In Ready Office Suite
    Move-In Ready Office Suite

    364 N Courtland St, East Stroudsburg, PA 18301

    $2,200/Mo

    Updated, ADA-accessible office suite includes a separate conference area and kitchenette, with rear off-street parking.

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    Multi-Unit Strip Mall
    Multi-Unit Strip Mall

    2583 Milford Road, East Stroudsburg, PA 18301

    $1,300/Mo
    1,000 sqft 1.03 AC lot

    Multiple suites are available within a 1990 strip-center property in the East Stroudsburg area.

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    East Stroudsburg, PA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in East Stroudsburg, PA with 39 listings featured on our commercial real estate exchange. The current inventory includes 277,213 square feet of properties with an estimated lease value of $843.72.

    Estimated lease rates for Commercial real estate in East Stroudsburg, PA begin at $1.20 SF/Yr, with an average of $25.57 SF/Yr and extend to $295 SF/Yr.
    East Stroudsburg, PA CRE market trends — vacancy, lease rates and price per SF, updated monthly
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    Most Searched ZIP Codes in East Stroudsburg, PA

    • 18301
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    Featured East Stroudsburg Real Estate Agencies

    Realmo connects you with licensed East Stroudsburg CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Your Neighborhood Realtor LLC
    1 Landmark Center East Stroudsburg, PA 18301
    Phone: (570) 424-8850
    www.pacrossroads.com
    Smart Way America Realty
    696 Seven Bridge rd East Stroudsburg, PA 18301
    Phone: (570) 371-5173
    www.smartwayamerica.com
    SER Commercial Real Estate, LLC
    215 Independence Rd East Stroudsburg, PA
    Phone: (570) 431-7400
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