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East Stroudsburg, PA Office Spaces for Lease

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23 properties
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Medical Office Space with Private Offices
Updated: Jul 22
Medical Office Space with Private Offices

526 Independence Road, East Stroudsburg, PA 18301

$18 SF/Yr
2,762 sqft 0.67 AC lot
Nine private offices within a medical or professional office suite
ADA‑accessible configuration
Reception and waiting area, conference room, and breakroom
Three restrooms
Just off I‑80 near numerous medical practices
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Creative Space with Exposed Beams
Updated: Oct 13
Creative Space with Exposed Beams

103 Five Star Lane, East Stroudsburg, PA 18301

$950/Mo
940 sqft 3.00 AC lot
940‑square‑foot creative space in a renovated historic bank barn
Original beams remain visible throughout the interior
ADA access
Located within the Keystone Innovation Zone, which offers tax credits to for‑profit companies
Owner willing to complete updates for qualified tenants
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Remodeled Medical Office Space
Remodeled Medical Office Space

296 E Brown Street, East Stroudsburg, PA 18301

$3,000/Mo
1,900 sqft 0.61 AC lot

ADA-compliant healthcare suite with private exam rooms, reception, waiting, and office areas for efficient patient service.

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Class A Medical Office Space
Class A Medical Office Space

526 Independence Rd, East Stroudsburg, PA 18301

$18 SF/Yr
2,762 sqft

Professional office suite with private rooms, patient areas, and convenient access near complementary medical practices.

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Remodeled Medical Office Space
Remodeled Medical Office Space

296 E Brown Street, East Stroudsburg, PA 18301

$3,000/Mo
1,900 sqft 0.61 AC lot

ADA-compliant healthcare suite with patient reception, private exam rooms, and a separate office.

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First-Floor Office Unit
First-Floor Office Unit

315 Dartmouth Dr., Unit #1, East Stroudsburg, PA 18301

$2,995/Mo
2,277 sqft 1.97 AC lot

Office space includes a kitchen and two ADA restrooms.

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Second-Floor Office Units
Second-Floor Office Units

78 S Courtland Street, East Stroudsburg, PA 18301

$1,850/Mo
2,500 sqft 0.06 AC lot

Bright office accommodation with private offices and a reception area in a brick building.

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Remodeled Medical Office Space
Remodeled Medical Office Space

C-296 E Brown St, East Stroudsburg, PA 18301

$3,000/Mo
1,900 sqft

ADA-compliant medical layout with reception, waiting, exam, and private office areas supports efficient practice operations.

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Office Units with Waiting Area
Office Units with Waiting Area

33 Dansbury Terrace, East Stroudsburg, PA 18301

$1,500/Mo
15,000 sqft 0.12 AC lot

Lease opportunity with two rooms, a kitchenette, front reception area, and allocated off-street parking.

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Office Units Across from Hospital
Office Units Across from Hospital

239 E Brown Street, East Stroudsburg, PA 18301

$4,168/Mo
27,573 sqft 1.87 AC lot

Multiple suites offer varying layouts and existing fit-outs, with shared on-site parking.

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Two-Room Office Suite
Two-Room Office Suite

33 Dansbury Ter, East Stroudsburg, PA 18301

$1,500/Mo
1,200 sqft

Lease space includes a kitchenette, waiting area, and allocated off-street parking.

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Office Units with Shared Parking
Office Units with Shared Parking

239 E Brown Street, East Stroudsburg, PA 18301

$6,094/Mo
27,573 sqft 1.87 AC lot

Office suites offer varied sizes and existing fit-outs, with shared on-site parking.

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Medical Office Suite with Elevator
Medical Office Suite with Elevator

507 Seven Bridge Road, East Stroudsburg, PA 18301

$3,250/Mo
2,165 sqft 5.12 AC lot

Office space offers ADA access, an interior courtyard, elevator service, and on-site parking for visitors and staff.

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Office Suites Across from Hospital
Office Suites Across from Hospital

Ste2-239 E Brown St, East Stroudsburg, PA 18301

$3,413/Mo
2,100 sqft

Multiple office suites are available, with rent covering electric, water, sewer, heat, and CAM.

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Office Units Across From Hospital
Office Units Across From Hospital

239 E Brown Street, East Stroudsburg, PA 18301

$3,413/Mo
27,573 sqft 1.87 AC lot

Office suites provide flexible layouts, existing fit-outs, and shared on-site parking.

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Medical Office Suite
Medical Office Suite

507 Seven Bridge Road, East Stroudsburg, PA 18301

$675/Mo
450 sqft 5.12 AC lot

Professional office setting with elevator access, ADA features, and on-site parking for patients, clients, and staff.

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Move-In Ready Office Suite
Move-In Ready Office Suite

364 N Courtland St, East Stroudsburg, PA 18301

$2,200/Mo

Updated, ADA-accessible office suite includes a separate conference area and kitchenette, with rear off-street parking.

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Executive Office Units with Conference Room
Executive Office Units with Conference Room

320 N Courtland Street, East Stroudsburg, PA 18301

$2,995/Mo
4,116 sqft 1.00 AC lot

Second-floor workspace combines private offices, shared areas, support rooms, and building services under a gross lease structure.

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Retail Suites for Lease
Retail Suites for Lease

37 Mill Creek Road, East Stroudsburg, PA 18301

Contact for pricing
900 sqft

Two retail suites are available, offering flexible space sizes for small businesses and service tenants.

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ADA-Compliant Office Units
ADA-Compliant Office Units

106 Shawnee Square Dr, First Floor, East Stroudsburg, PA 18301

$12 SF/Yr
4,610 sqft 1.60 AC lot

First-floor office space offers ADA-compliant access and flexible partitioning for professional, retail, or clinical uses.

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COMMERCIAL - East Stroudsburg, PA
COMMERCIAL - East Stroudsburg, PA

106 Shawnee Sq Dr, Unit FIRST, East Stroudsburg, PA 18301

$12 SF/Yr

Adaptable 4,610 SF space in high-traffic Shawnee Square.

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Medical Office Suite with ADA Access
Medical Office Suite with ADA Access

507 Seven Bridges Road, East Stroudsburg, PA 18301

$1,275/Mo
651 sqft 5.12 AC lot

ADA-accessible suite with elevator service, an interior courtyard, and on-site parking.

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106 Shawnee Square Dr, East Stroudsburg, PA 18301
106 Shawnee Square Dr, East Stroudsburg, PA 18301

106 Shawnee Sq Dr, East Stroudsburg, PA 18301

Contact for pricing

Office space for rent in the heart of Shawnee.

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Based on your search, we've compiled 49 Potential Opportunities for your consideration. Besides 23 Active listings in East Stroudsburg, PA, we suggest exploring alternatives. Similar 26 Properties for Sales.

Similar Spaces for Sale in East Stroudsburg, PA

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Two-Unit Medical Office Building
Two-Unit Medical Office Building

526-528 Independence Road, East Stroudsburg, PA 18301

$1,200,000
6,272 sqft 0.67 AC lot

Separate-access professional office configuration with one occupied suite and another available for use or leasing.

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East Stroudsburg, PA Office Spaces Lease Rates & Market Statistics

Browse 23 Office Spaces for lease in East Stroudsburg, PA on Realmo, a commercial real estate marketplace serving the East Stroudsburg area. The current inventory totals 130,852 square feet of properties — an average of ~5,700 SF per listing.

Asking lease rates for Office Spaces in East Stroudsburg start at $1.20 SF/Yr, average $13.18 SF/Yr, and reach $23.50 SF/Yr at the top of the market. That's a 20x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $13.18 SF/Yr is 35% below the Pennsylvania state average of $20.41 SF/Yr.

East Stroudsburg accounts for 28% of the 83 office spaces currently available across Monroe County, where nearby markets include Stroudsburg and Tobyhanna. By space type, the market includes 18 office units and 10 medical office space listings — office units typically offer the lowest entry point, while medical office space commands the highest rates.

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