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Cape Girardeau County, MO Medical Offices for Sale

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Renovated Downtown Commercial Property
$550,000
4,548 SF

Renovated Downtown Commercial Property

224 N Frederick St, Cape Girardeau, MO 63701

Versatile, renovated 11-bedroom property in downtown Cape Girardeau, Missouri.

  • Prime downtown location steps from dining, shopping, and campus.
  • Proven income‑producing property as a high‑demand sorority house.
  • Fully renovated in 2020 with 11 bedrooms and over 5,100 square feet.
  • Versatile property suitable for group housing, student rentals, or professional office space.
  • Generous lot with twenty‑five parking spaces.
Updated: Jan 9
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Cape Girardeau Commercial Property
Pending
$825,000
7,000 SF

Cape Girardeau Commercial Property

340 S Broadview St, Cape Girardeau, MO 63703

Well-maintained commercial property with over 7,000 square feet.

  • Over 7,000 square feet of usable space.
  • Highly visible and convenient location.
  • Suitable for a wide range of professional or medical uses.
  • Ample on‑site parking for staff and visitors.
  • ADA compliance throughout.
Updated: Dec 1, 2025
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Based on your search, we've compiled 4 Potential Opportunities for your consideration. Besides 2 Active listings in Cape Girardeau County, MO, we suggest exploring several alternatives: similar 1 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Versatile Commercial Building Near I-55
Pending
$570,000
3,096 SF

Versatile Commercial Building Near I-55

High-traffic location, built in 2017, suitable for diverse businesses.

5598 Us Highway 61 North, Jackson, MO 63755
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Explore Off-Market Properties in Cape Girardeau County, MO

Consider similar Off-Market properties in Cape Girardeau County, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

3049 William St

3049 William St

Medical offices • 79,122 SF
Value Estimation by Request
3049 William St, Cape Girardeau, MO 63703
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Cape Girardeau County, MO Medical Offices Investment Opportunities Market Analysis

Explore 3 medical offices for sale in Cape Girardeau County, MO on our real estate platform. These investment opportunities span a total of 57,525 square feet of properties for sale, with an estimated market value of $1,375,000.

Prices for medical spaces in Cape Girardeau County, MO start at $550,000, averaging $687,500, and reaching up to $825,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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