Medical Space

South Padre Island, TX Medical Office Space for Lease

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Port Isabel, TX Laguna Vista, TX Los Fresnos, TX Brownsville, TX
Multi-Suite Office Units
Updated: Jul 29, 2025
Multi-Suite Office Units

4405 Padre Blvd., South Padre Island, TX 78597

$8,000/Mo
3,360 sqft 62.60 AC lot
3,360 SF office property built in 1980
Multiple offices with varied sizes
Reception area, conference rooms, kitchen, and public restroom
Commercial zoning identified as Comm
Customer parking in front, plus additional parking behind and in another lot
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Based on your search, we've compiled 5 Potential Opportunities for your consideration. Besides 1 Active listings in South Padre Island, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Condo with Pylon Sign
Medical Office Condo with Pylon Sign

632 N Ed Carey Dr., Harlingen, TX 78550

$10,866/Mo
2,833 sqft

Multi-room layout includes sinks in most offices and can be adapted for medical or general office use.

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Commercial Lease
Commercial Lease

1911 Lubbock St. Suite A, Harlingen, TX 78550

$3,500/Mo
2,500 sqft

Medical Office Space · 2,500 SF

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Corner Medical Office Suite
Corner Medical Office Suite

5636 Southmost Rd. A, Brownsville, TX 78521

$3,500/Mo
3,500 sqft 1.07 AC lot

Multiple consultation rooms, reception and accessible restrooms support a range of professional office functions.

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Corner Medical Office Suite
Corner Medical Office Suite

5636 Southmost Rd. D, Brownsville, TX 78521

$1,000/Mo
1,000 sqft 1.07 AC lot

A multi-suite layout and on-site parking support medical and professional office use.

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South Padre Island, TX Medical Office Space Lease Rates & Market Statistics

Explore 1 Medical Office Space listing for lease in South Padre Island, TX on Realmo, a commercial real estate exchange covering the South Padre Island area. The current inventory totals 3,360 square feet of properties.

Medical Office Space lease rates in South Padre Island range from $28.57 SF/Yr at the entry level to $28.57 SF/Yr at the top of the market, averaging $28.57 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $28.57 SF/Yr, the local average runs 18% above Texas's state average of $24.23 SF/Yr.

South Padre Island accounts for 4% of the 26 medical office space listings currently available across Cameron County, where nearby markets include Harlingen and Brownsville. Medical Office Space is one of the more limited space types in South Padre Island, with just 1 listing currently available — a scarcity worth factoring into lease negotiations.

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