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    Sioux Falls, SD Medical Office Space for Lease

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    Medical Office Suite with Exam Rooms
    Updated: Aug 13
    Medical Office Suite with Exam Rooms

    2333 W 57th St, Sioux Falls, SD 57108

    Contact for pricing
    5,054 sqft
    5,054‑square‑foot medical office space with reception, exam rooms, offices, open workspace, breakroom, and storage
    21,600 VPD (2025) along 57th Street
    Convenient access to I‑229 and I‑29
    In‑suite restrooms included
    Co‑tenants include Pharmacy Specialties and Clinic, Denton Combs Center, and Dr. Meierhenry Women’s Health
    View details
    Medical Clinic Ready For Rent
    Updated: Jan 19, 2023
    Medical Clinic Ready For Rent

    4914-4930 N Cliff Ave, Sioux Falls, SD

    Contact for pricing
    3,840 sqft 1.51 AC lot
    Built‑out as a clinic, ideal for various medical practices.
    Plentiful parking** in front and rear of building.
    Available immediately.
    Excellent tenant mix.
    View details
    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 9 Potential Opportunities for your consideration. Besides 2 Active listings in Sioux Falls, SD, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Suite with Exam Rooms
    Medical Office Suite with Exam Rooms

    2015 Broadway St S, New Ulm, MN 56073

    Contact for pricing
    2,720 sqft

    Built-out clinical space offers reception, plumbing in most rooms, storage, and storefront windows for professional service use.

    View details
    Medical Office Suite with Exam Rooms
    Medical Office Suite with Exam Rooms

    2928 Hamilton Blvd, Sioux City, IA 51104

    $14 SF/Yr

    The layout includes a laboratory, a private office, and a large storage room alongside its clinical spaces.

    View details
    Move-in Ready Medical/Retail Space
    Move-in Ready Medical/Retail Space

    2023 S Broadway St, New Ulm, MN 56073

    $12 SF/Yr

    High-visibility retail space in Hy-Vee-anchored strip center.

    View details
    Medical Office Space Available
    Medical Office Space Available

    2421 Pierce Street, Sioux City, IA 51104

    $10 SF/Yr

    Medical office space featuring multiple exam rooms and a laboratory.

    View details

    Similar Spaces for Sale in Sioux Falls, SD

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Office Building with Walkout Lower Level
    Office Building with Walkout Lower Level

    1737 S Cleveland Ave, Sioux Falls, SD 57103

    $1,150,000
    6,284 sqft 0.53 AC lot

    Two levels offer private offices, open work areas, support facilities and independent exterior access to the lower floor.

    View details
    Office Building with Monument Signage
    Office Building with Monument Signage

    3800 S Kiwanis Ave, Sioux Falls, SD 57105

    Contact for pricing
    10,572 sqft

    Corner office property with access from both streets, monument signage, lawn irrigation, and an enclosed dumpster area.

    View details
    Medical and Daycare Office Building
    Medical and Daycare Office Building

    4800 N 4th Ave, Sioux Falls, SD 57104

    Contact for pricing
    49,424 sqft

    Freestanding building currently laid out for daycare with wet sprinkler system, heat pumps, and parking for 104 vehicles.

    View details

    Sioux Falls, SD Medical Office Space Lease Rates & Market Statistics

    Browse 2 Medical Office Space listings for lease in Sioux Falls, SD on Realmo, a commercial real estate marketplace serving the Sioux Falls area. The current inventory totals 8,894 square feet of properties.

    Medical Office Space is one of the more limited space types in Sioux Falls, with just 2 listings currently available — a scarcity worth factoring into lease negotiations. Also worth a look for tenants weighing alternatives: Office Units (78 listings) and Office buildings (7 listings) elsewhere in the Sioux Falls market.

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