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    Sioux Falls, SD
    Medical Space

    Sioux Falls, SD Medical Office Space for Lease

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    Tea, SD Harrisburg, SD Brandon, SD Hartford, SD Larchwood, IA Hills, MN Dell Rapids, SD
    Second-Level Class A Medical Office Suite
    Updated: Nov 25, 2025
    Second-Level Class A Medical Office Suite

    6709 S Minnesota Ave, Sioux Falls, SD 57108

    Contact for pricing
    3,552 sqft
    Sublease through 4/30/2027 for a second‑level Class A medical office suite
    3,552 SF floor plan with nine offices plus reception/waiting and break room
    Four offices include bathrooms and showers
    Recently renovated common areas with restrooms and a conference room
    Elevator and stairway access directly to the suite
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    Medical Office Building
    Updated: Feb 11
    Medical Office Building

    3400 S Holbrook Ave, Sioux Falls, SD 57106

    Contact for pricing
    3,185 sqft
    3,185‑square‑foot medical office building
    Used as a veterinary clinic since 2001
    Built in 1999
    Recently painted
    Located at a controlled intersection
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    Medical Office Suite with Operatories
    Medical Office Suite with Operatories

    1704 S Cleveland Ave, Sioux Falls, SD 57103

    Contact for pricing
    1,351 sqft

    Three operatories feature hands-free sinks, storage, and access to common area restrooms.

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    Medical Clinic Ready For Rent
    Medical Clinic Ready For Rent

    4914-4930 N Cliff Ave, Sioux Falls, SD

    Contact for pricing
    3,840 sqft 1.51 AC lot

    Clinic space available for medical, therapy, or dental practices.

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    Office
    Office

    6709 S Minnesota Ave, Sioux Falls, SD 57108

    Contact for pricing

    Medical Office Space

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    Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 5 Active listings in Sioux Falls, SD, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Suite with Exam Rooms
    Medical Office Suite with Exam Rooms

    2015 Broadway St S, New Ulm, MN 56073

    Contact for pricing
    2,720 sqft

    Built-out clinical space offers reception, plumbing in most rooms, storage, and storefront windows for professional service use.

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    Move-in Ready Medical/Retail Space
    Move-in Ready Medical/Retail Space

    2023 S Broadway St, New Ulm, MN 56073

    $12 SF/Yr

    High-visibility retail space in Hy-Vee-anchored strip center.

    View details
    Medical Office Space For Rent
    Medical Office Space For Rent

    5865 Sunnybrook Drive, Sioux City, IA 51106

    $28 SF/Yr

    Former dialysis center near Unity Point St. Lukes.

    View details
    Medical Office Space Available
    Medical Office Space Available

    2421 Pierce Street |, Sioux City, IA 51104

    $10 SF/Yr

    Medical office space featuring multiple exam rooms and a laboratory.

    View details

    Similar Spaces for Sale in Sioux Falls, SD

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Sioux Falls Adaptable Commercial Building
    Sioux Falls Adaptable Commercial Building

    4800 N 4th Ave, Sioux Falls, SD 57104

    $2,250,379
    49,424 sqft

    49,424 SF vacant building suitable for daycare, medical, or office.

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    Office and Dental Building
    Office and Dental Building

    2200 S Minnesota Ave, Sioux Falls, SD 57105

    Contact for pricing

    Office and dental building along Minnesota Avenue with leased upper-level dental space and main level space available.

    View details
    Medical Office Condo Suite
    Medical Office Condo Suite

    6709 S Minnesota Ave, Sioux Falls, SD 57108

    Contact for pricing

    Office condo features a lobby and waiting area, private offices, exam rooms, and in-suite restrooms.

    View details

    Sioux Falls, SD Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Sioux Falls, SD with 5 listings featured on our commercial real estate exchange. The current inventory includes 11,928 square feet of properties.
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    Most Searched ZIP Codes in Sioux Falls, SD

    • 57108
    • 57103
    • 57106

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