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    Portsmouth, NH Office Units for Lease

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    Manchester, NH Nashua, NH Concord, NH
    41 results
    Downtown Portsmouth Modern Office Space
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    Downtown Portsmouth Modern Office Space

    299 Hanover Street, Portsmouth, NH 03801

    Modern office space in downtown Portsmouth with parking and amenities.

    • Prime downtown Portsmouth location with access to 100+ restaurants.
    • Large, modern 2000 sq ft office space with open layout.
    • Includes conference room, kitchen, two bathrooms, tech room, and large storage.
    • Abundant natural light with tall ceilings.
    • Central air conditioning and natural gas forced hot air heating.
    Updated: Jan 5
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    Downtown Portsmouth Office For Lease
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    Downtown Portsmouth Office For Lease

    159 Middle Street, Portsmouth, NH 03801

    Office space for lease in downtown Portsmouth, available immediately.

    • Prime downtown Portsmouth location, walk to everything!
    • Includes heat, electric, and cleaning of common areas.
    • On‑site parking included.
    • Features a kitchenette area.
    • Located in a classic Portsmouth building with authentic woodwork and trim.
    Updated: Feb 5
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    Retail/Office Space in Portsmouth
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    Retail/Office Space in Portsmouth

    Updated retail/office space with patio in Portsmouth's North End.

    33 Deer Street, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suites Available
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    Downtown Portsmouth Office Suites Available

    Move-in-ready office suites in a vibrant downtown location.

    10 Vaughan, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant downtown location.

    10 Vaughan, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant, walkable downtown location.

    10 Vaughan, Portsmouth, NH 03801
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    Retail/Office Space For Lease
    $17 SF/Yr
    4,100 SF

    Retail/Office Space For Lease

    Retail/office space with ample parking and convenient highway access.

    72 Mirona Rd, Portsmouth, NH
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    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    Versatile office space available for lease in Portsmouth, New Hampshire.

    500 Maplewood Ave unit: A, Portsmouth, NH 03801
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    Versatile Commercial Space on Lafayette Road
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    Versatile Commercial Space on Lafayette Road

    Adaptable space suitable for medical, retail, restaurant, or office use.

    750 Lafayette Road, Portsmouth, NH 03801
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    First-Class Office Space Available
    $14 SF/Yr
    5,257 SF

    First-Class Office Space Available

    First-class office space with panoramic views and central location.

    15 Rye St, Portsmouth, NH
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    Modern Office Space Available
    $24 SF/Yr
    3,679 SF

    Modern Office Space Available

    Contemporary office space in premier business corridor, available April 2026.

    75 Portsmouth Blvd, Portsmouth, NH
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    High-End Office Space Available
    $40 SF/Yr
    10,524 SF

    High-End Office Space Available

    Office space with river views in desirable Portsmouth location.

    1 Harbour Place, Portsmouth, NH
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    Portsmouth Office Space For Lease
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    Portsmouth Office Space For Lease

    Versatile office space in Portsmouth, accessible from city or bypass.

    500 Maplewood Avenue, Portsmouth, NH 03801
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    Office Space Sublease Opportunity
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    6,000 SF

    Office Space Sublease Opportunity

    6,000 SF office space available for sublease.

    2 International Dr, Portsmouth, NH 3801
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    Office Space Near Downtown Portsmouth
    $19 SF/Yr
    10,244 SF

    Office Space Near Downtown Portsmouth

    Office spaces with natural light and convenient location near I-95.

    135 Commerce Way, Portsmouth, NH
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    Office or Medical Office Space
    $16 SF/Yr
    2,027 SF

    Office or Medical Office Space

    Office or medical space in Portsmouth's Pease Tradeport.

    14 Manchester Square, Portsmouth, NH
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    Class A Office Space Available
    Contact for pricing
    3,172 SF

    Class A Office Space Available

    Class A office space for rent in Portsmouth, NH.

    210 Commerce Way, Portsmouth, NH
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    Class A Office Space Available
    $18 SF/Yr
    16,027 SF

    Class A Office Space Available

    Flexible office suites with modern amenities and ample parking.

    273 Corporate Dr, Portsmouth, NH
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    Office Space Available For Rent
    $35 SF/Yr
    4,870 SF

    Office Space Available For Rent

    4,870 SF office space available on the 2nd floor.

    100 Market St, Portsmouth, NH 3801
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    Portsmouth Office Space For Rent
    Contact for pricing
    5,100 SF

    Portsmouth Office Space For Rent

    Professional office space available in a premier Portsmouth building.

    1000 Market St Bldg 2, Portsmouth, NH
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    Second Floor Office with Privacy
    $400 /Mo
    402 SF

    Second Floor Office with Privacy

    Private second-floor office space with natural light and ample parking.

    170 West Rd, Portsmouth, NH 3801
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    Turnkey Penthouse Executive Office Suite
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    3,921 SF

    Turnkey Penthouse Executive Office Suite

    Exclusive penthouse office suite with private elevator access and six offices.

    30 Penhallow Street, Portsmouth, NH
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    Economical Office and Warehouse Space
    $12 SF/Yr
    2,539 SF

    Economical Office and Warehouse Space

    Flexible office and warehouse space near major routes.

    200 International Drive, Portsmouth, NH
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    Energy Efficient Office Space
    $17 SF/Yr
    5,249 SF

    Energy Efficient Office Space

    Three-story office building in Pease International Tradeport.

    100 International Dr, Portsmouth, NH
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    Portsmouth, NH Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Portsmouth, NH with 41 listings featured on our commercial real estate exchange. The current inventory includes 606,834,360 square feet of properties with an estimated lease value of $51 SF/Yr.

    Estimated lease rates for Office Units in Portsmouth, NH begin at $10 SF/Yr, with an average of $17 SF/Yr and extend to $24 SF/Yr.
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