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    Seneca, SC Individual Retail Properties for Sale

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    Historical Brick Building in Seneca
    $999,949

    Historical Brick Building in Seneca

    235 Main St, Seneca, SC 29678

    Three-level, 15,600 SF building in Seneca's Opportunity Zone.

    • Historical 3‑level brick building.
    • Free‑standing corner location, one block from Ram Cat Alley.
    • Opportunity Zone location.
    • Main level currently used as retail space.
    • Hardwood and concrete flooring throughout.
    Updated: Sep 23, 2025
    View details
    Based on your search, we've compiled 259 Potential Opportunities for your consideration. Besides 1 Active listings in Seneca, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 252 Off-Market properties to explore as potential leads, plus 2 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Commercial Building on Highway 123
    $1,349,990
    0.48 Acres

    Commercial Building on Highway 123

    Commercial building in Clemson with ample parking and high traffic.

    990 Tiger Blvd, Clemson, SC 29631
    View details
    Commercial Space in Downtown Clemson
    Pending
    $699,000

    Commercial Space in Downtown Clemson

    Rare opportunity to purchase commercial space in downtown Clemson.

    105 Sloan St, Clemson, SC 29631
    View details
    Downtown Walhalla Mixed-Use Gem
    $875,000
    16,515 SF

    Downtown Walhalla Mixed-Use Gem

    16,515 SF, Vacant, Redevelopment Opportunity

    222 Main St, Walhalla, SC 29691
    View details
    Historic Retail Buildings on Main
    $1,300,000
    6,130 SF

    Historic Retail Buildings on Main

    Renovated retail spaces with historic charm and modern amenities.

    214-218 E Main St, Walhalla, SC 29691
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Land in Seneca
    $3,500,000
    4.33 Acres

    Prime Commercial Land in Seneca

    4.3 acres with high visibility, ideal for retail development.

    1018 North 1St St, Seneca, SC 29678
    View details
    Highway Frontage Commercial Land Opportunity
    $985,000
    1.45 Acres

    Highway Frontage Commercial Land Opportunity

    1.45 acres with highway frontage, ideal for development or lease.

    994 Lots, Seneca, SC 29678
    View details

    Explore Off-Market Properties in Seneca, SC

    Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    901 North 1St St

    901 North 1St St

    Individual retail properties • 0.23 Acres
    Value Estimation by Request
    901 North 1St St, Seneca, SC 29678
    View details
    1631 Sandifer Blvd

    1631 Sandifer Blvd

    CONVENIENCE STORE • 5,275 SF
    Value Estimation by Request
    1631 Sandifer Blvd, Seneca, SC 29678-0906
    View details
    605 En 1st St

    605 En 1st St

    RETAIL STORES (PERSONAL SERVICES) • 3,200 SF
    Value Estimation
    $105,000
    605 En 1st St, Seneca, SC 29678-2823
    View details
    114 Walnut St

    114 Walnut St

    RETAIL STORES (PERSONAL SERVICES) • 2,057 SF
    Value Estimation
    $70,000
    114 Walnut St, Seneca, SC 29678-2722
    View details
    222 En 1st St

    222 En 1st St

    RETAIL STORES (PERSONAL SERVICES) • 21,940 SF
    Value Estimation
    $1,000,000
    222 En 1st St, Seneca, SC 29678
    View details
    403 Main St

    403 Main St

    RETAIL STORES (PERSONAL SERVICES) • 3,600 SF
    Value Estimation by Request
    403 Main St, Seneca, SC 29678-2745
    View details
    926 Friendship Rd

    926 Friendship Rd

    RETAIL STORES (PERSONAL SERVICES) • 1,984 SF
    Value Estimation
    $135,000
    926 Friendship Rd, Seneca, SC 29678-5342
    View details
    1007 By Pass 123

    1007 By Pass 123

    FINANCIAL BUILDING • 3,160 SF
    Value Estimation
    $715,000
    1007 By Pass 123, Seneca, SC 29678-4762
    View details
    445 By Pass 123

    445 By Pass 123

    RETAIL STORES (PERSONAL SERVICES) • 3,400 SF
    Value Estimation by Request
    445 By Pass 123, Seneca, SC 29678-0842
    View details
    166 Bilo Pl

    166 Bilo Pl

    RETAIL STORES (PERSONAL SERVICES) • 11,680 SF
    Value Estimation by Request
    166 Bilo Pl, Seneca, SC 29678-2563
    View details
    225 Main St

    225 Main St

    RETAIL STORES (PERSONAL SERVICES) • 11,158 SF
    Value Estimation by Request
    225 Main St, Seneca, SC 29678-3245
    View details
    123 Townville St

    123 Townville St

    RETAIL STORES (PERSONAL SERVICES) • 8,864 SF
    Value Estimation
    $890,000
    123 Townville St, Seneca, SC 29678-3254
    View details
    9910 Clemson Blvd

    9910 Clemson Blvd

    RETAIL STORES (PERSONAL SERVICES) • 2,100 SF
    Value Estimation
    $65,000
    9910 Clemson Blvd, Seneca, SC 29678-0832
    View details
    10899 Clemson Blvd

    10899 Clemson Blvd

    CONVENIENCE STORE • 4,712 SF
    Value Estimation
    $90,000
    10899 Clemson Blvd, Seneca, SC 29678-1303
    View details
    533 By Pass 123

    533 By Pass 123

    RETAIL STORES (PERSONAL SERVICES) • 7,000 SF
    Value Estimation by Request
    533 By Pass 123, Seneca, SC 29678-0845
    View details
    4060 Keowee School Rd

    4060 Keowee School Rd

    RETAIL STORES (PERSONAL SERVICES) • 2,496 SF
    Value Estimation by Request
    4060 Keowee School Rd, Seneca, SC 29672-0640
    View details
    116 Ram Cat Aly

    116 Ram Cat Aly

    RETAIL STORES (PERSONAL SERVICES) • 5,872 SF
    Value Estimation
    $70,000
    116 Ram Cat Aly, Seneca, SC 29678-3262
    View details
    115 En 2nd St

    115 En 2nd St

    FINANCIAL BUILDING • 6,468 SF
    Value Estimation
    $235,000
    115 En 2nd St, Seneca, SC 29678-3201
    View details
    101 Wn 1st St

    101 Wn 1st St

    RETAIL STORES (PERSONAL SERVICES) • 903 SF
    Value Estimation by Request
    101 Wn 1st St, Seneca, SC 29678-3247
    View details
    123 En 1st St

    123 En 1st St

    RETAIL STORES (PERSONAL SERVICES) • 4,420 SF
    Value Estimation by Request
    123 En 1st St, Seneca, SC 29678-3240
    View details
    319 Main St

    319 Main St

    RETAIL STORES (PERSONAL SERVICES) • 10,400 SF
    Value Estimation by Request
    319 Main St, Seneca, SC 29678-2743
    View details
    711 Wn 1st St

    711 Wn 1st St

    RETAIL STORES (PERSONAL SERVICES) • 1,800 SF
    Value Estimation
    $130,000
    711 Wn 1st St, Seneca, SC 29678-2526
    View details
    901 Wn 1st St

    901 Wn 1st St

    RETAIL STORES (PERSONAL SERVICES) • 1,462 SF
    Value Estimation
    $70,000
    901 Wn 1st St, Seneca, SC 29678-2530
    View details

    Seneca, SC Individual Retail Properties Investment Opportunities Market Analysis

    Explore 251 individual retail properties for sale in Seneca, SC on our real estate platform. These investment opportunities span a total of 1,974,141 square feet of properties for sale, with an estimated market value of $32,140,000.

    Prices for individual retail properties in Seneca, SC start at $50,000, averaging $535,666, and reaching up to $2,695,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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    Browse Individual retail properties for Sale Near Seneca, SC

    Popular Searches in Seneca, SC

    Most Searched ZIP Codes in Seneca, SC

    • 29678
    • 29672

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