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    Portsmouth, NH Commercial Real Estate for Sale

    36 results
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    Historic Portsmouth Mixed-Use Gem
    $3,600,000
    0.11 Acres

    Historic Portsmouth Mixed-Use Gem

    56 Market St, Portsmouth, NH 03801

    Mixed-use property with commercial space and residential apartments in Portsmouth.

    • Prime location in the heart of Portsmouth, NH, offering convenient access to amenities, transportation, and cultural attractions.
    • Versatile mixed‑use property with over 6,000 sqft of commercial space and two apartments, providing diverse income potential.
    • Historic building, formerly the Portsmouth Brewery, offering unique character and appeal.
    • Spacious penthouse apartment with 14 ft ceilings.
    • Massive first floor with soaring ceilings and exposed brick walls.
    Updated: Jan 2
    View details
    Luxury Commercial Condo in Portsmouth
    $2,300,000
    0.11 Acres

    Luxury Commercial Condo in Portsmouth

    20 Ladd St, Portsmouth, NH 03801

    Meticulously renovated 4,600 sq.ft. commercial condo with residential conversion potential.

    • Premier downtown Portsmouth location, steps from restaurants, shops, and the waterfront.
    • Rare potential for residential conversion of a 4,600± sq.ft. luxury commercial condominium.
    • Meticulously renovated historic 1860 building blending architectural character with modern amenities.
    • Bright, flexible open layout with nine private offices, two conference rooms, reception area, and three bathrooms.
    • Professional‑grade kitchen with commercial stainless steel appliances, hood system, and refrigeration.
    Updated: Oct 20, 2025
    View details
    Mixed-Use Development Opportunity, Portsmouth
    $6,800,000
    0.20 Acres

    Mixed-Use Development Opportunity, Portsmouth

    Mixed-use development opportunity in the heart of Portsmouth, New Hampshire.

    266 State St, Portsmouth, NH 03801
    View details
    Waterfront Lot Near Downtown Portsmouth
    $1,000,000
    0.41 Acres

    Waterfront Lot Near Downtown Portsmouth

    Waterfront mixed-use property near downtown Portsmouth, offering versatile development opportunities.

    98 Cornwall St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suites
    $1,200,000
    3,186 SF

    Downtown Portsmouth Office Suites

    Recently renovated office suites in vibrant downtown Portsmouth.

    8 Vaughan St, Portsmouth, NH 03801
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    Portsmouth Art Studio For Sale
    $235,000

    Portsmouth Art Studio For Sale

    Two-level art studio with natural light and garage access.

    871 Islington St, Portsmouth, NH 03801
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    Turnkey Restaurant Opportunity in Portsmouth
    $200,000

    Turnkey Restaurant Opportunity in Portsmouth

    Turnkey restaurant with dining rooms, bars, patio in downtown Portsmouth.

    175 High St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suites
    $300,000

    Downtown Portsmouth Office Suites

    Recently renovated office suites in a prime downtown location.

    10 Vaughan St, Portsmouth, NH 03801
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    Prime Portsmouth Commercial Building For Sale
    $595,000
    0.11 Acres

    Prime Portsmouth Commercial Building For Sale

    Versatile 1,470 SF building in high-traffic Portsmouth location.

    1290 Woodbury Ave, Portsmouth, NH 03801
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    Waterfront Lot Near Downtown Portsmouth
    $1,000,000
    0.16 Acres

    Waterfront Lot Near Downtown Portsmouth

    Waterfront lot near downtown Portsmouth with redevelopment potential.

    94 Langdon St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suites Available
    $425,000

    Downtown Portsmouth Office Suites Available

    Recently renovated office suites in a vibrant, walkable downtown location.

    10 Vaughan St, Portsmouth, NH 03801
    View details
    Historic Mixed-Use Portsmouth Gem
    $2,400,000

    Historic Mixed-Use Portsmouth Gem

    Historic Portsmouth mixed-use property with commercial and residential spaces.

    48 Market St, Portsmouth, NH 03801
    View details
    Historic Portsmouth Office Building For Sale
    $3,300,000
    0.25 Acres

    Historic Portsmouth Office Building For Sale

    Landmark Portsmouth building, ideal for professional offices or business.

    144 Washington St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suites Available
    $500,000

    Downtown Portsmouth Office Suites Available

    Recently renovated office suites in a prime downtown location.

    10 Vaughan St, Portsmouth, NH 03801
    View details
    Portsmouth Commercial Office Condominium
    $250,000

    Portsmouth Commercial Office Condominium

    Commercial office condominium in Portsmouth, renovated in 2024.

    118 Maplewood Ave, Portsmouth, NH 03801
    View details
    Historic Portsmouth Brewery Building
    $4,500,000
    10,434 SF

    Historic Portsmouth Brewery Building

    Prime Location, Versatile Spaces, Investment Opportunity

    56 Market St, Portsmouth, NH 03801
    View details
    Portsmouth Office Condo - Prime Location
    $300,000

    Portsmouth Office Condo - Prime Location

    Downtown Portsmouth office, renovated 2024.

    118 Maplewood Ave, Portsmouth, NH 03801
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    Portsmouth Office Space: North End Gem
    Contact for pricing

    Portsmouth Office Space: North End Gem

    Class A Office, Vibrant Location, 2,325 RSF

    12 Portwalk Pl, Portsmouth, NH 03801
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    Portsmouth Medical Office Condo
    $1,130,000

    Portsmouth Medical Office Condo

    Prime Location, Two Vacant Units

    100 Griffin Rd, Portsmouth, NH 03801
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    Historic Portsmouth Commercial Gem
    $2,400,000
    5,575 SF

    Historic Portsmouth Commercial Gem

    Prime Location, Mixed-Use Investment

    48 Market St, Portsmouth, NH 03801
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    Portsmouth Office Space for Lease
    Contact for pricing

    Portsmouth Office Space for Lease

    Prime Portsmouth Office, Ample Parking

    875 Greenland Rd, Portsmouth, NH 03801
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    Portsmouth Retail & Office Space
    Contact for pricing
    6,200 SF

    Portsmouth Retail & Office Space

    Prime Portsmouth location, flexible lease options.

    150 Mirona Road Ext, Portsmouth, NH 03801
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    Portsmouth Retail & Office Space
    Contact for pricing
    6,200 SF

    Portsmouth Retail & Office Space

    Prime Portsmouth location, flexible lease options.

    150 Mirona Road Ext, Portsmouth, NH 03801
    View details
    Portsmouth Retail/Office Space
    Contact for pricing

    Portsmouth Retail/Office Space

    Prime Portsmouth location, 4100+ sq ft available.

    72 Mirona Road Ext, Portsmouth, NH 03801
    View details

    Portsmouth, NH Commercial Real Estate Investment Opportunities Market Analysis

    Explore 1330 commercial real estate investment opportunities in Portsmouth, NH with 36 listings featured on our commercial real estate marketplace. The current inventory includes 8,742,978 square feet of properties with an estimated value of $255,170,000.

    Estimated prices for commercial real estate in Portsmouth, NH begin at $210,000, with an average of $1,509,881 and extend to $14,860,000.

    In Portsmouth, NH, current investment values show:

    • Retail properties positioned at $1,506,333
    • Individual retail properties measuring $1,737,051
    • Mixed-use properties assessed at $1,090,468
    • Investment properties calculated at $810,172
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    Browse Commercial real estate for Sale Near Portsmouth, NH

    Popular Searches in Portsmouth, NH

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    Most Searched ZIP Codes in Portsmouth, NH

    • 03801
    • 03869

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