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    Middlesex County, MA Commercial Real Estate for Sale

    368 results
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    Groton Commercial Development Opportunity
    $825,000
    2.80 Acres

    Groton Commercial Development Opportunity

    797 Boston Rd, Groton, MA 01450

    Prime land parcel in Groton, MA, for diverse development.

    • Approved Special Permit for 24 age‑restricted multifamily units allows for immediate development.
    • Zoned RA, permitting a variety of development options including residential, childcare, and religious uses.
    • Strategically located in a high‑visibility, mixed‑use corridor.
    • Positioned at a signaled intersection adjacent to a supermarket and other businesses.
    • Benefits from strong daily traffic counts and excellent visibility.
    Updated: Nov 11, 2025
    View details
    Lowell Mixed-Use Investment Opportunity
    $795,000
    3,774 SF

    Lowell Mixed-Use Investment Opportunity

    525 Chelmsford St, Lowell, MA 01851

    Mixed-use property with commercial space and residential unit in Lowell.

    • Mixed‑use property featuring commercial space and a large residential unit.
    • Two retail storefronts boast high street visibility and traffic on Chelmsford Street.
    • Off‑street parking for 10+ vehicles plus a carport.
    • Spacious 4‑5 bedroom residential unit with a flexible floor plan.
    • Unfinished 2nd floor offers expansion potential for commercial space.
    Updated: Dec 7, 2025
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    Somerville Mixed-Use Building For Sale
    $1,749,000
    3,115 SF

    Somerville Mixed-Use Building For Sale

    Mixed-use building with income potential or condo conversion opportunity.

    148 Pearl, Somerville, MA 02145
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    Mixed-Use Building Near UMASS Lowell
    $1,300,000
    7,178 SF

    Mixed-Use Building Near UMASS Lowell

    Five-unit mixed-use building with retail space and residential units.

    169-171 Salem St, Lowell, MA 01854
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    Approved Commercial Lot Ready to Build
    $599,000
    0.69 Acres

    Approved Commercial Lot Ready to Build

    Approved commercial parcel in high-visibility location, ready for development.

    1905 Lakeview Ave, Dracut, MA 01826
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    Hudson Development Opportunity: 15+ Acres
    $594,900
    15.39 Acres

    Hudson Development Opportunity: 15+ Acres

    15.39 acres in Hudson, near major retailers, Route 85.

    Washington Street, Hudson, MA 01749
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    Hudson Land Parcel For Sale
    $199,900
    9.98 Acres

    Hudson Land Parcel For Sale

    9.98 acre wooded parcel near shopping and major routes.

    Washington St, Hudson, MA 01749
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    Prime Watertown Retail Building For Sale
    $1,275,000
    3,047 SF

    Prime Watertown Retail Building For Sale

    Free-standing corner retail building with high visibility in Watertown.

    475 Main St, Watertown, MA 2472
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    Renovated Commercial Space Near Station
    $550,000
    1,048 SF

    Renovated Commercial Space Near Station

    1,048 SF renovated commercial space across from Oak Grove T-station.

    1 Glenwood St #6, Malden, MA 2148
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    Updated Office Space Available
    $399,000
    750 SF

    Updated Office Space Available

    Office space with reception area and private offices for rent.

    394 Lowell St, Lexington, MA
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    Renovated Commercial Condo in Winchester
    $400,000
    621 SF

    Renovated Commercial Condo in Winchester

    Turnkey office condo in downtown Winchester near amenities and transit.

    63 Shore Road #14, Winchester, MA 1890
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    Auto Garage/Warehouse on Large Lot
    $1,099,000
    2,257 SF

    Auto Garage/Warehouse on Large Lot

    Three-bay auto garage/warehouse on 1.74-acre lot for sale.

    340 Main St, North Reading, MA 2180
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    Groton Retail, Office, Restaurant Space
    $349,000
    3,234 SF

    Groton Retail, Office, Restaurant Space

    Raw space in mixed-use development, Groton town center.

    134 Main St LL, Groton, MA 1450
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    Marlborough Office Condo For Sale
    $239,000
    72,000 SF

    Marlborough Office Condo For Sale

    Office condominium with immediate availability, convenient location, and modern amenities.

    28 Lord Road, Marlborough, MA 1752
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    Watertown Retail Redevelopment Opportunity
    Contact for pricing
    6,400 SF

    Watertown Retail Redevelopment Opportunity

    6,400 SF free-standing building for re-use or redevelopment.

    1084 Belmont Street, Watertown, MA 2472
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    Renovated Mixed-Use Building Near I-495
    Contact for pricing
    3,600 SF

    Renovated Mixed-Use Building Near I-495

    Two-story renovated building with medical office and luxury apartment.

    205 Chelmsford Street, Chelmsford, MA 1824
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    Malden Auto Service Property Available
    Contact for pricing
    5,673 SF

    Malden Auto Service Property Available

    5,673 SF auto service property with flexible industrial zoning.

    314-320 Eastern Avenue, Malden, MA 1248
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    Renovated Office/Retail Space Available
    $2,945,000
    5,200 SF

    Renovated Office/Retail Space Available

    Move-in ready office/retail space with high visibility and accessibility.

    31 1st St, Lowell, MA
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    North Reading Flex Building For Sale
    Contact for pricing
    7,560 SF

    North Reading Flex Building For Sale

    7,560 SF flex building near Route I-93.

    73 Concord Street, North Reading, MA 1864
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    Medical Office Condo Near I-495
    Contact for pricing
    3,633 SF

    Medical Office Condo Near I-495

    Multi-use medical office condo with easy highway access.

    28 Lord Rd Suites 225 & 255, Marlborough, MA 1752
    View details
    Retail Building in Sudbury Center
    $750,000
    3,444 SF

    Retail Building in Sudbury Center

    Retail building for sale in Sudbury's Village Business District.

    337 Boston Post Road, Sudbury, MA 1776
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    Melrose Retail Investment Opportunity
    Contact for pricing
    4,448 SF

    Melrose Retail Investment Opportunity

    Prime Melrose location near MBTA, ideal for retail investment.

    437 Franklin Street, Melrose, MA USA, Melrose, MA 2176
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    Renovated Commercial Space in Malden
    $2,450,000
    2,000 SF

    Renovated Commercial Space in Malden

    Versatile, renovated 2,000 sq ft commercial space on 0.34 acres.

    69 Newland, Malden, MA 2148
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    Retail Space in North Billerica
    Contact for pricing
    5,649 SF

    Retail Space in North Billerica

    Retail space with flexible zoning in a high-traffic location.

    161 Boston Rd, North Billerica, MA 1862
    View details

    Middlesex County, MA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 368 commercial real estate for sale in Middlesex County, MA, showcased through 368 active listings on our real estate platform. These investment opportunities span a total of 3,034,105 square feet of properties for sale, with an estimated market value of $143,424,399.

    Sale prices for business properties in Middlesex County, MA start at $35,000, averaging $4,097,839, and reaching up to $28,855,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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