Barnstable County, MA Commercial Real Estate for Sale

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Orleans Office Building For Sale
Updated: Dec 30, 2025
Orleans Office Building For Sale

8 Cardinal Lane, Orleans, MA 02653

$3,900,000
14,341 sqft · 2.68 AC lot
Prime location in the heart of Orleans, near Main Street retail, Route 6A, and US Route 6, offering superior accessibility.
Substantial 14,340 sq ft office building on a large 2.6+ acre private lot with exceptional parking facilities.
Excellent condition of the building, featuring a warm reception area and four wings of offices and meeting space.
Versatile property with potential for professional office, mixed‑use, residential, or investment opportunities.
Convenient access to Cape Cod Rail Trail / Bike Trail.
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8 Cardinal Lane, Orleans, MA 02653

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Multi-Use Commercial Building
Updated: Jun 22
Multi-Use Commercial Building

491 Iyannough Road, Hyannis, MA 02601

$1,300,000
3,215 sqft · 0.36 AC lot
3,215 sq ft commercial property with a spacious main level plus second‑floor office/storage and a full basement
Garage/warehouse included for added commercial flexibility
High‑visibility corner location at the Airport Rotary, abutting Staples Plaza at the intersection of Route 28, Route 132 and Barnstable Road
Across from Cape Cod Gateway Airport, with access to nearby Downtown Hyannis
Utilities: public water and public sewer
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Multi-Story Office Building
Multi-Story Office Building

697 Main Street, Chatham, MA 02633

$2,399,000
3,097 sqft · 0.26 AC lot

Three finished office levels with central air and prominent Main Street frontage for client-facing and back-office uses.

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Industrial Flex Facility with Offices
Industrial Flex Facility with Offices

9 Rayber Road, Orleans, MA 02653

$1,800,000
1,920 sqft · 0.57 AC lot

Well-maintained flex building with dual service bays, workshop space, and dedicated offices for industrial and service operations.

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Multi-Tenant Commercial Building For Sale
Multi-Tenant Commercial Building For Sale

254 Shore Road, Pocasset, MA 02559

$1,525,000
10,800 sqft · 0.85 AC lot

Commercial property with office and restaurant units in Pocasset, MA.

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Multi-Tenant Medical Office Building
Multi-Tenant Medical Office Building

765 Attucks Lane, Hyannis, MA 02601

$3,495,000
17,713 sqft · 2.32 AC lot

Multi-story, multi-tenant office facility with elevator access and ample surface parking on a waterfront-view site.

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Medical Office Condominium with Exam Rooms
Medical Office Condominium with Exam Rooms

37 Edgerton Drive, North Falmouth, MA 02556

$599,900
2,284 sqft · 2.87 AC lot

Remodeled medical condo with HVAC, multiple exam rooms, and onsite parking, offered with a lease in place.

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West Barnstable Commercial-Residential Opportunity
West Barnstable Commercial-Residential Opportunity

1049 Main Street, West Barnstable, MA 02668

$1,450,000
6,684 sqft · 1.09 AC lot

Multi-use property with business and residential potential on Route 6A.

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Office Showroom Building on Route 28
Office Showroom Building on Route 28

103 Main Street, Dennis Port, MA 02639

$799,000
3,692 sqft · 1.18 AC lot

Owner-user building with integrated showroom, office, and production support near Route 28 exposure.

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Two-Story Office Building with Storage
Two-Story Office Building with Storage

31 Meetinghouse Road, South Chatham, MA 02659

$1,999,999
5,712 sqft · 1.21 AC lot

Two-story office building with a separate seven-unit storage bay building, renovated in 2013, near Rt. 28.

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Waterfront Retail and Restaurant Building
Waterfront Retail and Restaurant Building

87 Water Street, Woods Hole, MA 02543

$3,295,000
3,744 sqft · 0.07 AC lot

Two-story property with an operating market and 68-seat restaurant overlooking Eel Pond.

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Barnstable Harbor Waterfront Legacy Property
Barnstable Harbor Waterfront Legacy Property

164 Beale Way, Barnstable, MA 02630

$1,995,000
2,968 sqft · 0.50 AC lot

Iconic waterfront property with pier and marine workshops.

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Boutique Hotel with Rooftop Deck
Boutique Hotel with Rooftop Deck

12 Winthrop Street, Provincetown, MA 02657

$5,900,000
6,674 sqft · 0.15 AC lot

Recently renovated boutique hotel offering 14 rooms, suites, and multiple outdoor decks with onsite laundry and staff space.

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Bed & Breakfast with Bay-View Patio
Bed & Breakfast with Bay-View Patio

164 Commercial Street, Provincetown, MA 02657

$2,895,000
2,736 sqft · 0.08 AC lot

Iconic guesthouse offers a bay-view patio, private courtyard, and eight well-appointed suites with private baths and split AC.

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Well-Maintained Retail Building with Parking
Well-Maintained Retail Building with Parking

303 Orleans Road, North Chatham, MA 02650

$1,850,000
5,101 sqft · 0.92 AC lot

Well-maintained retail building with parking and three leased units along Route 28.

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Waterfront Restaurant Building
Waterfront Restaurant Building

193A Commercial Street, Provincetown, MA 02657

$2,995,000
3,074 sqft · 0.32 AC lot

Recently renovated waterfront building with a substantial interior and an outdoor deck for dining or entertaining.

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Renovated Restaurant Condo with Kitchen
Renovated Restaurant Condo with Kitchen

247 Main Street, Hyannis, MA 02601

$699,000
2,783 sqft

Turnkey, renovated restaurant condo with a spacious commercial kitchen and licensed seating across multiple levels.

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Medical and Office Mixed-Use Building
Medical and Office Mixed-Use Building

320 Gifford Street, Falmouth, MA 02540

$649,000
3,214 sqft

Rare opportunity within the Homeport complex, offering strong visibility and flexible space for medical or professional use.

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Commercial Condo in Provincetown Heart
Commercial Condo in Provincetown Heart

182 Commercial Street, Provincetown, MA 02657

$1,325,000
413 sqft · 0.12 AC lot

Turnkey commercial condo in high-traffic Provincetown location.

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Dennis Port Motel Near Beach
Dennis Port Motel Near Beach

183 Captain Chase Road, Dennis Port, MA 02639

$1,950,000
3,586 sqft · 0.38 AC lot

Motel with 9 units near the beach in Dennis Port.

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Turn-Key Mixed-Use Property
Turn-Key Mixed-Use Property

712 Main Street, Hyannis, MA 02601

$2,000,000
3,415 sqft · 0.25 AC lot

Renovated office suites with an added second-floor apartment, plus on-site parking for eight cars.

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Route 134 Commercial Property
Route 134 Commercial Property

970 Route 134, Dennis, MA 02638

$2,200,000
10,101 sqft · 0.87 AC lot

Commercial property with retail, office, and storage space for sale.

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Mixed-Use Retail and Apartment Building
Mixed-Use Retail and Apartment Building

21 S Orleans Road, Orleans, MA 02653

$1,350,000
4,416 sqft · 0.46 AC lot

Street-level retail with on-site parking plus two upstairs apartments and a walk-out lower level for office or storage.

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Prime Commercial Street Retail Opportunity
Prime Commercial Street Retail Opportunity

251 Commercial Street, Provincetown, MA 02657

$3,249,000
4,598 sqft · 0.08 AC lot

Storied Provincetown commercial property with retail space and staff housing.

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Barnstable County, MA Commercial Real Estate Market Trends and Statistics

Explore 274 commercial real estate for sale in Barnstable County, MA, showcased through 274 active listings on our real estate platform. These investment opportunities span a total of 1,517,188 square feet of properties for sale, with an estimated market value of $592,074,922.

Sale prices for business properties in Barnstable County, MA start at $39,100, averaging $1,903,777, and reaching up to $25,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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