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    Barnstable County, MA Commercial Real Estate for Sale

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    368 properties
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    Modern Two-Building Flex Property
    Updated: Aug 24
    Modern Two-Building Flex Property

    41 Echo Road, Mashpee, MA 02649

    $2,950,000
    8,162 sqft 0.95 AC lot
    8,162‑square‑foot commercial property on a 0.95‑acre parcel
    Two‑building configuration includes a separate 1,438‑square‑foot structure
    Primary building exceeds 6,000 square feet and was built in 2024
    Finished basement includes men’s and women’s locker rooms, break room, vault, and elevator
    Located near Routes 28 and 151 and US Route 6
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    Retail Building with Two Suites
    Updated: Sep 27
    Retail Building with Two Suites

    28 Barnstable Road, Hyannis, MA 02601

    $995,000
    4,323 sqft 0.27 AC lot
    4,323‑square‑foot retail building on a 0.27‑acre lot
    Two ground‑floor suites and an approximately 1,242‑square‑foot second floor
    Lash Boutique occupies an approximately 1,589‑square‑foot street‑level suite
    Approximately 1,407‑square‑foot ground‑floor suite and second floor are prepared for commercial buildout
    Zoned DMS; served by public water and sewer
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    Downtown Storefront Property
    Downtown Storefront Property

    61 Main Street, Buzzards Bay, MA 02532

    $795,000
    11,276 sqft 0.37 AC lot

    Historic commercial building with DTC zoning, public utilities, and a tenant-at-will antique store.

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    Renovated Mixed-Use Property
    Renovated Mixed-Use Property

    574 Main Street, Hyannis, MA 02601

    $1,199,000
    4,032 sqft

    Two-level commercial and residential building with ground-floor business space and a two-bedroom apartment above.

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    Conventional Restaurant with Residences
    Conventional Restaurant with Residences

    2653 Main Street, Chatham, MA 02633

    $950,000
    2,252 sqft 0.22 AC lot

    Restaurant property includes a commercial kitchen and attached residential components.

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    Operating Restaurant with Event Building
    Operating Restaurant with Event Building

    70 W Main Street, Wellfleet, MA 02667

    $695,000
    8,195 sqft 1.24 AC lot

    The property combines an active restaurant with a separate structure affected by a 2023 fire.

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    Two-Story Office Building
    Two-Story Office Building

    29 Bassett Lane, Hyannis, MA 02601

    $2,895,000
    15,552 sqft 0.53 AC lot

    Brick professional property near downtown Hyannis with adaptable floors, on-site parking, and public water and sewer service.

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    Hotel with Separate Living Quarters
    Hotel with Separate Living Quarters

    36 Route 28, West, Harwich, MA 02671

    $929,000
    5,000 sqft 0.77 AC lot

    A year-round inn combines six ensuite guest rooms with a separate three-bedroom residence.

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    Retail Space with Harbor-Facing Deck
    Retail Space with Harbor-Facing Deck

    193 Commercial Street, Provincetown, MA 02657

    $595,000
    1,450 sqft 0.32 AC lot

    Two connected commercial suites offer flexible gallery, office, retail, and creative-use configurations.

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    Multilevel Storefront Building
    Multilevel Storefront Building

    193 Commercial Street, Provincetown, MA 02657

    $1,525,000
    2,998 sqft 0.32 AC lot

    Flexible commercial layout with retail, upper-level workspace, basement storage, separate stair access, and a harbor-facing deck.

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    Converted Office Building
    Converted Office Building

    Harwich Port, MA 02646

    $1,399,000
    4,000 sqft

    Nearly 4,000 sq. ft. office building with reception, conference rooms, individual offices, and ample off-street parking.

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    Leased Storefront with Basement Storage
    Leased Storefront with Basement Storage

    193 Commercial Street, Provincetown, MA 02657

    $975,000
    1,548 sqft 0.32 AC lot

    Single-unit retail condominium with basement storage and an established boutique tenant.

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    Harborfront Restaurant With Deck
    Harborfront Restaurant With Deck

    193A Commercial Street, Provincetown, MA 02657

    $2,495,000
    3,074 sqft 0.32 AC lot

    Restaurant property with interior dining space and a waterfront deck overlooking Provincetown Harbor.

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    Corner Mixed-Use Property
    Corner Mixed-Use Property

    315 Commercial Street Ste 1, Provincetown, MA 02657

    $2,448,000
    1,871 sqft

    Two-level commercial property combines leased retail with office and residential space.

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    Furnished Lodging Inn
    Furnished Lodging Inn

    36 Route 28, West Harwich, MA 02671

    $929,000
    5,032 sqft 0.77 AC lot

    Licensed for year-round lodging, the property includes separate living quarters and two additional buildings.

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    Standalone Retail Building
    Standalone Retail Building

    1772 Main Street, Chatham, MA 02633

    $625,000
    600 sqft 0.17 AC lot

    The compact, single-tenant property includes dedicated parking and public water and sewer service.

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    Multi-Suite Office Building
    Multi-Suite Office Building

    2957 Falmouth Rd, Osterville, MA

    $1,800,000
    4,200 sqft

    Two floors provide separate office areas and bathrooms for a flexible business configuration.

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    Freestanding Restaurant Building
    Freestanding Restaurant Building

    859 Main Street, Chatham, MA 02633

    $2,750,000
    1,920 sqft 0.63 AC lot

    Leased restaurant property with recent updates, on-site parking, and public utilities.

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    Downtown Hyannis Office Building
    Downtown Hyannis Office Building

    33 Bassett Ln, Barnstable, MA 02601

    $1,999,000
    8,000 sqft

    Recently renovated professional office building with central AC, gas heat, and shared space across multiple floors.

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    Post-and-Beam Mixed-Use Property
    Post-and-Beam Mixed-Use Property

    1049 Main Street, West Barnstable, MA 02668

    $1,450,000
    6,684 sqft 1.09 AC lot

    Historic multi-use building with private offices, exam rooms, separate entrances, and an attached residence requiring restoration.

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    Restaurant Condominium with Commercial Kitchen
    Restaurant Condominium with Commercial Kitchen

    46 Route 6a # 48, Orleans, MA 02653

    $3,300,000
    4,156 sqft

    Includes a dining room, bar, atrium seating, and a fully equipped commercial kitchen.

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    17-Unit Motel with Manager Residence
    17-Unit Motel with Manager Residence

    382 main Street, Falmouth, MA 02540

    $2,750,000
    5,460 sqft 0.26 AC lot

    Established lodging property with updated guest rooms and an on-site residence suited to owner or manager occupancy.

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    Downtown Hyannis Commercial Building For Sale
    Downtown Hyannis Commercial Building For Sale

    460 Main Street C1, Hyannis, MA 02601

    $1,999,000
    6,216 sqft 0.33 AC lot

    Highly visible commercial building in the heart of Downtown Hyannis.

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    Mixed-Use Property with Bay Views
    Mixed-Use Property with Bay Views

    134 Commercial Street, Provincetown, MA 02657

    $2,395,000
    1,770 sqft 0.04 AC lot

    Street-level space opens onto Commercial Street for retail, office, gallery, studio, or other permitted client-facing use.

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    Barnstable County, MA Commercial Real Estate Market Trends and Statistics

    Explore 368 commercial real estate for sale in Barnstable County, MA, showcased through 368 active listings on our real estate platform. These investment opportunities span a total of 1,260,395 square feet of properties for sale, with an estimated market value of $656,072,379.

    Sale prices for business properties in Barnstable County, MA start at $54,000, averaging $2,179,642, and reaching up to $25,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Barnstable County Real Estate Agencies

    Realmo connects you with licensed Barnstable County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Thomas D. Brown Real Estate Associates
    PO Box 2003, 300 Route 6 Truro, MA 02666
    Phone: 15084871112
    www.thomasdbrown.com
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