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    Barnstable County, MA Commercial Real Estate for Sale

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    Boston, MA Worcester, MA Springfield, MA
    365 results
    Waterfront Retail and Restaurant Opportunity
    $2,999,000
    3,744 SF

    Waterfront Retail and Restaurant Opportunity

    87 Water Street, Woods Hole, MA 02543

    Landmark property with market and restaurant in Woods Hole, MA.

    • Landmark waterfront property with established market and 68‑seat restaurant.
    • Prime location on Water Street in Woods Hole, overlooking Eel Pond.
    • Turnkey operation with existing inventory included.
    • High visibility and foot traffic, near marine research facilities, ferries, and amenities.
    • Inviting indoor spaces and dramatic upper‑level dining views.
    Updated: Apr 23
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    West Barnstable Commercial-Residential Opportunity
    $1,450,000
    6,684 SF

    West Barnstable Commercial-Residential Opportunity

    1049 Main Street, West Barnstable, MA 02668

    Multi-use property with business and residential potential on Route 6A.

    • Rare commercial‑residential multi‑use property on Route 6A.
    • High visibility and accessibility on a picturesque route.
    • 6,400 sq. ft. former medical office building with post‑and‑beam construction.
    • Multiple private offices, exam rooms, and separate entrances.
    • Attached residence primed for restoration.
    Updated: May 7
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    Multi-Tenant Commercial Building For Sale
    $1,525,000
    10,800 SF

    Multi-Tenant Commercial Building For Sale

    Commercial property with office and restaurant units in Pocasset, MA.

    254 Shore Road, Pocasset, MA 02559
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    Renovated Restaurant in Hyannis Market
    $750,000
    2,783 SF

    Renovated Restaurant in Hyannis Market

    Completely renovated restaurant in Hyannis' Business Improvement District for sale.

    247 Main Street, Hyannis, MA 02601
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    Restaurant Space in Downtown Hyannis
    $499,000
    2,256 SF

    Restaurant Space in Downtown Hyannis

    Turnkey restaurant with flexible space in the heart of Hyannis.

    517 Main Street, Hyannis, MA 02601
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    Wellfleet Office with Expansion Potential
    $849,000
    2,186 SF

    Wellfleet Office with Expansion Potential

    2,189 SF office on 0.79 acres with expansion potential.

    2548 STATE HWY RTE 6, Wellfleet, MA 02667
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    Centerville Commercial Opportunity
    $499,000
    1,736 SF

    Centerville Commercial Opportunity

    Commercial property in Centerville, MA, near beaches and high-traffic area.

    628 Craigville Beach Road, Centerville, MA 02632
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    Orleans Landmark: Mixed-Use Opportunity
    $1,350,000
    4,416 SF

    Orleans Landmark: Mixed-Use Opportunity

    In-town location with high visibility, apartments, and retail space.

    21 S Orleans Road, Orleans, MA 02653
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    Hyannis Commercial Condominium For Sale
    $545,000
    2,790 SF

    Hyannis Commercial Condominium For Sale

    Commercial condominium in Hyannis, ideal for investment or relocation.

    68 Center Street, Hyannis, MA 02601
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    Orleans Office Building For Sale
    $3,900,000
    14,341 SF

    Orleans Office Building For Sale

    14,340 SF office building on 2.6+ acres in Orleans.

    8 Cardinal Lane, Orleans, MA 02653
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    Orleans Landmark: Mixed-Use Opportunity
    $1,350,000
    4,416 SF

    Orleans Landmark: Mixed-Use Opportunity

    In-town mixed-use property with retail space and apartments.

    21 S Orleans Road, Orleans, MA 02653
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    Orleans Commercial Condo on Main
    $1,399,000
    3,595 SF

    Orleans Commercial Condo on Main

    3,595 SF commercial condo in the center of town.

    32 Main Street, Orleans, MA 02653
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    South Chatham Mixed-Use Property
    $2,300,000
    5,712 SF

    South Chatham Mixed-Use Property

    Two-story office building with storage units on 1.21 acres.

    31 Meetinghouse Road, South Chatham, MA 02659
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    Prime Corner Commercial Condo, Hyannis
    $849,000
    4,259 SF

    Prime Corner Commercial Condo, Hyannis

    High-visibility 4,200 SF commercial condo in downtown Hyannis.

    615 Main Street, Hyannis, MA 02601
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    Mixed-Use Commercial Opportunity, Eastham
    $950,000
    2,442 SF

    Mixed-Use Commercial Opportunity, Eastham

    High-visibility mixed-use property with commercial kitchen and short-term rental.

    5030 State Highway, Eastham, MA 02642
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    Waterfront Commercial Property in Provincetown
    $2,995,000
    3,074 SF

    Waterfront Commercial Property in Provincetown

    Renovated 3,074 SF waterfront property with 968 SF deck.

    193A Commercial Street, Provincetown, MA 02657
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    Orleans Professional Office For Sale
    $850,000
    812 SF

    Orleans Professional Office For Sale

    Well-known Orleans office building with high visibility and ample parking.

    170 Massachusetts 6A, Orleans, MA 02653
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    Retail Property in Merchant Square
    $599,995
    1,188 SF

    Retail Property in Merchant Square

    Thriving Merchant Square location with established business and real estate.

    12 Merchants Landing, Sandwich, MA 02563
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    Prime Commercial Street Retail Opportunity
    $3,249,000
    4,598 SF

    Prime Commercial Street Retail Opportunity

    Storied Provincetown commercial property with retail space and staff housing.

    251 Commercial Street, Provincetown, MA 02657
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    Hyannis Commercial Space For Sale
    $1,999,000
    13,242 SF

    Hyannis Commercial Space For Sale

    Prime commercial space in downtown Hyannis with diverse tenant mix.

    338 Main Street, Hyannis, MA 02601
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    Prime Hyannis Retail Condo
    $329,000
    532 SF

    Prime Hyannis Retail Condo

    Highly visible commercial condo in the heart of Hyannis.

    569 Main Street, Hyannis, MA 02601
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    Established Physical Therapy Office
    $399,000
    933 SF

    Established Physical Therapy Office

    Thriving physical therapy practice for sale in Brewster, Massachusetts.

    5 Bay State Court, Brewster, MA 02631
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    Mixed-Use Investment in Downtown Falmouth
    $5,250,000
    11,114 SF

    Mixed-Use Investment in Downtown Falmouth

    Prime mixed-use property with retail and residential spaces.

    199 Main Street, Falmouth, MA 02540
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    Falmouth Office Condo For Sale
    $249,000
    1,401 SF

    Falmouth Office Condo For Sale

    Class A office condo in mixed-use Heritage Place, Falmouth.

    205 Worcester Court, Falmouth, MA 02540
    View details

    Barnstable County, MA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 365 commercial real estate for sale in Barnstable County, MA, showcased through 365 active listings on our real estate platform. These investment opportunities span a total of 1,208,213 square feet of properties for sale, with an estimated market value of $500,590,889.

    Sale prices for business properties in Barnstable County, MA start at $39,100, averaging $1,986,471, and reaching up to $25,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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