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    Hyannis, MA Commercial Real Estate for Sale

    16 results
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    Hyannis Commercial Business Bay/Office Unit
    $330,000
    1,414 SF

    Hyannis Commercial Business Bay/Office Unit

    270 Communication Way, Hyannis, MA 02601

    Commercial business bay/office unit for sale in Hyannis, MA.

    • Prime location at the front entrance of the sought‑after Communication Way Industrial Development.
    • 1,414 sq ft commercial unit with two floors, multiple offices, and mezzanine space.
    • Excellent frontage and signage opportunities.
    • Overhead door to the rear, suitable for trades, storage, or sales.
    • Close proximity to US Route 6, exits 6 and 7.
    Updated: Jan 5
    View details
    Versatile Commercial Property in Hyannis
    $899,000
    4,033 SF

    Versatile Commercial Property in Hyannis

    307 Falmouth Rd, Hyannis, MA 02601

    High-visibility commercial property with flexible space in a vibrant location.

    • High‑traffic location in the heart of Hyannis with outstanding visibility.
    • 4,000+ square feet of flexible commercial space.
    • Features 8 private office spaces.
    • Suitable for office, retail, or a combination of both.
    • Zoning HB may allow for multifamily potential (buyer to verify).
    Updated: Dec 10, 2025
    View details
    Hyannis Retail Property For Sale
    $599,000
    2,822 SF

    Hyannis Retail Property For Sale

    Retail property in Hyannis, MA, with redevelopment potential.

    181 Spring St, Hyannis, MA 02601
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    Turn-Key Investment in Hyannis, MA
    $2,000,000
    3,415 SF

    Turn-Key Investment in Hyannis, MA

    Fully renewed mixed-use property with immediate income potential.

    712 Main St, Hyannis, MA 02601
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    Established Restaurant Business For Sale
    $698,000
    16,239 SF

    Established Restaurant Business For Sale

    Turnkey restaurant and bar with high traffic and loyal clientele.

    950 Iyannough Rd, Hyannis, MA 02601
    View details
    Historic Hyannis Main Street Property
    $574,900

    Historic Hyannis Main Street Property

    2,200 SF space ideal for restaurant or retail.

    615 Main St, Hyannis, MA 02601
    View details
    Hyannis Office Building For Sale
    $1,350,000
    6,285 SF

    Hyannis Office Building For Sale

    Two-section building with law and medical offices in Hyannis.

    83 Main St, Hyannis, MA 02668
    View details
    Historic Hyannis Main Street Property
    $574,900
    2,228 SF

    Historic Hyannis Main Street Property

    Prime location suitable for retail, restaurant, or office use.

    615-617 Main St, Hyannis, MA 02668
    View details
    Mixed-Use Property with Income Potential
    $625,000

    Mixed-Use Property with Income Potential

    Mixed-use property with residential and commercial rental units.

    657 Yarmouth Rd, Hyannis, MA 02601
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    Versatile Commercial Property in Hyannis
    $899,000

    Versatile Commercial Property in Hyannis

    Commercial property with flexible space, ideal for various professional uses.

    307 Falmouth Rd, Hyannis, MA 02601
    View details
    Hyannis Office Building For Sale
    $826,000

    Hyannis Office Building For Sale

    Fully occupied office building in Hyannis with 7.5% cap rate.

    243 South St, Hyannis, MA 02601
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    Established Uniform Supply Business For Sale
    $849,000

    Established Uniform Supply Business For Sale

    Profitable uniform and equipment supplier serving first responders for 35+ years.

    11 Enterprise Rd, Hyannis, MA 02601
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    Reimagined Restaurant in Historic Hyannis
    $2,195,000

    Reimagined Restaurant in Historic Hyannis

    Premiere restaurant with modern updates in the heart of Hyannis.

    488 South St, Hyannis, MA 02601
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    Hyannis Route 28 Retail Opportunity
    $665,000
    1,300 SF

    Hyannis Route 28 Retail Opportunity

    Restaurant building for sale on busy Route 28 in Hyannis.

    225 Iyannough Rd, Hyannis, MA 02601
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    Redevelopment Opportunity in Cape Cod
    $599,000

    Redevelopment Opportunity in Cape Cod

    Flex/industrial property with redevelopment potential in thriving commercial market.

    181 Spring St, Hyannis, MA 02601
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    Hyannis Duplex Commercial/Residential Building
    $389,000

    Hyannis Duplex Commercial/Residential Building

    Duplex in the heart of Hyannis with 40+ year business.

    705 Main St, Hyannis, MA 02601
    View details
    Based on your search, we've compiled 1417 Potential Opportunities for your consideration. Besides 16 Active listings in Hyannis, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 1395 Off-Market properties to explore as potential leads, plus 2 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Barnstable Land with Development Potential
    $1,150,000
    6.24 Acres

    Barnstable Land with Development Potential

    Vacant land parcel suitable for residential or business ventures.

    Ln Phinney's, Barnstable, MA 02630
    View details
    Barnstable Land For Sale
    $250,000
    1.27 Acres

    Barnstable Land For Sale

    Vacant land parcel in a rapidly growing area.

    230 Attucks Ln, Barnstable, MA 02630
    View details
    Former Craigville General Store
    $799,000

    Former Craigville General Store

    Mixed-use property near beaches with high visibility and parking.

    628 Craigville Beach Rd, Centerville, MA 02632
    View details
    Centerville Office Suite - Bayberry Square
    Contact for pricing
    418 SF

    Centerville Office Suite - Bayberry Square

    Prime 418 sq ft office space, seller financing.

    1645 Falmouth Rd Unit, Centerville, MA 02632
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Downtown Hyannis Redevelopment Opportunity
    $745,000

    Downtown Hyannis Redevelopment Opportunity

    Prime redevelopment land in Hyannis' commercial hub.

    43 Pleasant St, Hyannis, MA 02601
    View details
    Prime Commercial Lot in Hyannis
    $475,000
    0.66 Acres

    Prime Commercial Lot in Hyannis

    Commercial lot in high-traffic area, ideal for development.

    16 Iyannough Rd, Hyannis, MA 02601
    View details

    Explore Off-Market Properties in Hyannis, MA

    Consider similar Off-Market properties in Hyannis, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3,024 SF Flex Condo Unit

    3,024 SF Flex Condo Unit

    3,024 SF Flex Condo Prime Location on Main Street in Hyannis
    Value Estimation by Request
    615 Main St, Hyannis, MA 02601
    View details
    615 Main St

    615 Main St

    Commercial real estate • 2,228 SF
    Value Estimation by Request
    615 Main St, Hyannis, MA 02601
    View details
    108 Breeds Hl Rd

    108 Breeds Hl Rd

    MANUFACTURING (LIGHT) • 57,516 SF
    Value Estimation by Request
    108 Breeds Hl Rd, Hyannis, MA 02601-1860
    View details
    217 Thornton Dr

    217 Thornton Dr

    INDUSTRIAL (GENERAL) • 2,400 SF
    Value Estimation by Request
    217 Thornton Dr, Hyannis, MA 02601-8105
    View details
    105 Ferndoc St

    105 Ferndoc St

    MANUFACTURING (LIGHT) • 45,000 SF
    Value Estimation by Request
    105 Ferndoc St, Hyannis, MA 02601-2065
    View details
    40 Channel Pt Rd

    40 Channel Pt Rd

    MARINE FACILITY/BOARD REPAIRS • 0.24 Acres
    Value Estimation by Request
    40 Channel Pt Rd, Hyannis, MA 02601
    View details
    80 Airport Rd

    80 Airport Rd

    WAREHOUSE, STORAGE • 61,678 SF
    Value Estimation by Request
    80 Airport Rd, Hyannis, MA 02601-1802
    View details
    220 Communication Way

    220 Communication Way

    LUMBERYARD, BUILDING MATERIALS • 1,680 SF
    Value Estimation by Request
    220 Communication Way, Hyannis, MA 02601
    View details

    Hyannis, MA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 1341 commercial real estate investment opportunities in Hyannis, MA with 16 listings featured on our commercial real estate marketplace. The current inventory includes 143,149,044 square feet of properties with an estimated value of $306,008,000.

    Estimated prices for commercial real estate in Hyannis, MA begin at $100,000, with an average of $713,305 and extend to $23,970,000.

    In Hyannis, MA, current investment values show:

    • Retail properties positioned at $702,065
    • Automotive properties measuring $429,776
    • Individual retail properties assessed at $1,114,674
    • Other commercial real estate calculated at $765,844
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    Browse Commercial real estate for Sale Near Hyannis, MA

    Popular Searches in Hyannis, MA

    Most Searched ZIP Codes in Hyannis, MA

    • 02601
    • 02668

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