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    San Luis Obispo, CA Commercial Real Estate for Sale

    74 results
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    San Luis Obispo Commercial Condo
    $390,000
    2,296 SF

    San Luis Obispo Commercial Condo

    2475 Victoria Ave, San Luis Obispo, CA 93401

    Commercial condo with outdoor patio, ideal for restaurant/café.

    • Large outdoor patio space (1,000 SF) in addition to 1,275 SF interior space.
    • Suitable for restaurant/cafe use due to grease trap and venting systems.
    • Located in Victoria Crossing, a community with 33 existing residential flats.
    • Onsite parking with 11 spaces, in addition to street parking.
    • New construction (built in 2023).
    Updated: Nov 24, 2025
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    6.55 Acres in San Luis Obispo
    $1,045,000
    285,318.00 Acres

    6.55 Acres in San Luis Obispo

    Calle Crotalo, San Luis Obispo, CA 93401

    Premium land with water access near downtown San Luis Obispo.

    • 6.55 acres of premium land in a desirable location.
    • Includes a "will serve" letter from Afuero Water Company with two water meter allotments.
    • Opportunity to split the property for a second APN.
    • Minutes from downtown San Luis Obispo (SLO) with easy access to amenities.
    • Surrounded by rolling hills and picturesque views.
    Updated: Feb 18
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    Winery Production Facility in Edna Valley
    $15,000,000
    43,218 SF

    Winery Production Facility in Edna Valley

    Turnkey winery with high-capacity production and expansion potential.

    4915 Orcutt Rd, San Luis Obispo, CA 93401
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    Downtown San Luis Obispo Investment
    $1,150,000
    5,000 SF

    Downtown San Luis Obispo Investment

    Commercial property in downtown San Luis Obispo with investment potential.

    283 Higuera St, San Luis Obispo, CA 93401
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    San Luis Obispo Commercial Land
    $3,900,000
    156,380.00 Acres

    San Luis Obispo Commercial Land

    3.59 acres in a planned community, retail potential.

    2040 Prado Rd, San Luis Obispo, CA 93401
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    San Luis Obispo Retail Space
    $390,000

    San Luis Obispo Retail Space

    Retail space with outdoor patio in San Luis Obispo, CA.

    2475 Victoria Ave, San Luis Obispo, CA 93401
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    San Luis Obispo Agricultural Cannabis Property
    $750,000
    22,000 SF

    San Luis Obispo Agricultural Cannabis Property

    123.67-acre agricultural property with cannabis entitlement in San Luis Obispo.

    2675 Cuyama Hwy, San Luis Obispo, CA 93254
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    Updated Office Near Downtown SLO
    $475,000

    Updated Office Near Downtown SLO

    Versatile 1,290 SF office suite near downtown San Luis Obispo.

    1035 Peach St, San Luis Obispo, CA 93401
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    Bright Office Suite with Views
    $450,000

    Bright Office Suite with Views

    Third-floor office suite with natural light and city views.

    1035 Peach St, San Luis Obispo, CA 93401
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    285-Acre Vineyard and Citrus Ranch
    $6,900,000
    12,153,240.00 Acres

    285-Acre Vineyard and Citrus Ranch

    Premier San Luis Obispo ranch with vineyard, citrus, and rangeland.

    5502 Los Ranchos Rd, San Luis Obispo, CA 93401
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    Medical Condo with Onsite Parking
    $525,000

    Medical Condo with Onsite Parking

    Well-appointed medical condo near Highway 101 with onsite parking.

    1250 Peach St, San Luis Obispo, CA 93401
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    Profitable Laundromat Business Opportunity
    $799,000

    Profitable Laundromat Business Opportunity

    Established laundromat business with growth potential in prime location.

    2020 Parker St, San Luis Obispo, CA 93401
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    Iconic Restaurant in Downtown SLO
    $895,000

    Iconic Restaurant in Downtown SLO

    Two-story restaurant in the heart of San Luis Obispo.

    815 Palm St, San Luis Obispo, CA 93401
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    Medical Office Space Available
    $2,830,000

    Medical Office Space Available

    Prime medical office space in San Luis Obispo.

    689 Tank Farm Rd, San Luis Obispo, CA 93401
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    Mixed-Use Development Opportunity in SLO
    $999,000

    Mixed-Use Development Opportunity in SLO

    Pre-planned mixed-use development with income potential near Cal Poly.

    1142 Montalban St, San Luis Obispo, CA 93405
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    Income-Producing Retail Center For Sale
    $6,995,000

    Income-Producing Retail Center For Sale

    Retail center with 15 suites, 100% occupied, great location.

    12300 Los Osos Valley Rd, San Luis Obispo, CA 93405
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    Downtown San Luis Obispo Retail Space
    $1,800,000

    Downtown San Luis Obispo Retail Space

    Prime retail space in a highly visible downtown location.

    715 Higuera St, San Luis Obispo, CA 93401
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    Income-Producing Retail Center For Sale
    $6,995,000

    Income-Producing Retail Center For Sale

    Fully occupied retail center on a busy commercial corridor.

    12300 Los Osos Valley Rd, San Luis Obispo, CA 93405
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    Versatile Industrial Building For Sale
    $8,250,000

    Versatile Industrial Building For Sale

    46,242 SF industrial building on 2.67 acres.

    143 Suburban Rd, San Luis Obispo, CA 93401
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    Mixed-Use Development Opportunity in SLO
    $999,000

    Mixed-Use Development Opportunity in SLO

    Pre-planned mixed-use development with income potential near Cal Poly.

    1142 Montalban St, San Luis Obispo, CA 93405
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    Winery Production Facility in Edna Valley
    $15,000,000

    Winery Production Facility in Edna Valley

    Turnkey winery with high-capacity production and expansion potential.

    4915 Orcutt Rd, San Luis Obispo, CA 93401
    View details
    Historic Ranch Estate Near San Luis Obispo
    $3,450,000
    2,400 SF

    Historic Ranch Estate Near San Luis Obispo

    189-acre ranch with residences, barns, and equestrian facilities.

    1498 O'sconnor Way, San Luis Obispo, CA 93405
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    Medical Office Space Available
    $2,830,000

    Medical Office Space Available

    Prime medical office space with high visibility in San Luis Obispo.

    689 Tank Farm Rd, San Luis Obispo, CA 93401
    View details

    San Luis Obispo, CA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 54 commercial real estate for sale in San Luis Obispo, CA, showcased through 74 active listings on our real estate platform. These investment opportunities span a total of 19,254,043,156 square feet of properties for sale, with an estimated market value of $19,594,000.

    Sale prices for business properties in San Luis Obispo, CA start at $1,045,000, averaging $3,918,800, and reaching up to $9,999,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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