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    Horry County, SC Commercial Real Estate for Lease

    230 results
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    Myrtle Beach Office/Retail Space
    $2,218 / Mo
    2,360 SF

    Myrtle Beach Office/Retail Space

    720 Main St, Myrtle Beach, SC 29577

    Standalone building with high visibility, suitable for office or retail.

    • Ideal central Myrtle Beach location with high visibility.
    • Standalone building offering independence and control.
    • Excellent accessibility from newly realigned Hwy 501.
    • Suitable for retail or professional office use.
    • Ample natural light due to large window facing main street.
    Updated: Mar 2
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    Versatile Flex Space in Myrtle Beach
    $4,750 / Mo
    4,110 SF

    Versatile Flex Space in Myrtle Beach

    716 8Th Ave N, Myrtle Beach, SC 29577

    Adaptable commercial space for lease in the Arts & Innovation District.

    • Highly visible flex‑use commercial space in the heart of Myrtle Beach's Arts & Innovation District.
    • Approximately 4,500 sq ft across two floors, suitable for office, storefront, and warehouse/operational needs.
    • Features a reception area, multiple offices, conference room, two kitchens, and two restrooms.
    • Rear garage door provides flexibility for deliveries, storage, or service‑based operations.
    • Flexible zoning and no on‑site parking requirements offer versatility for various commercial uses.
    Updated: Feb 18
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    Professional Office Suite in Murrells
    $525 / Mo
    81 SF

    Professional Office Suite in Murrells

    Executive office suite with shared amenities on Highway 17.

    3955 Highway 17 Byp, Murrells Inlet, SC 29576
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    Highway 17 Retail Space
    $6,250 / Mo
    4,500 SF

    Highway 17 Retail Space

    Retail space with highway frontage in established Myrtle Beach building.

    10589 N Kings Hwy, Myrtle Beach, SC 29572
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    Murrells Inlet Office Space
    $2,400 / Mo
    1,250 SF

    Murrells Inlet Office Space

    Multi-tenant office/retail/medical building with easy highway access. Available 4/1/26.

    637 Bellamy Ave, Murrells Inlet, SC 29576
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    Murrells Inlet Office Space
    $1,665 / Mo
    1,250 SF

    Murrells Inlet Office Space

    Multi-tenant office/retail/medical building with 1,250 SF available 4/1/26.

    637 Bellamy Ave, Murrells Inlet, SC 29576
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    Executive Office Space in Surfside
    $475 / Mo
    120 SF

    Executive Office Space in Surfside

    Executive office space available with included utilities and amenities.

    1500 Business St, Surfside Beach, SC 29575
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    Surfside Beach Freestanding Office Building
    $2,500 / Mo
    1,100 SF

    Surfside Beach Freestanding Office Building

    Freestanding office building for lease in downtown Surfside Beach.

    825 1St Ave N, Surfside Beach, SC 29575
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    Office Warehouse in Murrells Inlet
    $3,000 / Mo
    2,200 SF

    Office Warehouse in Murrells Inlet

    Office warehouse space for lease with great location and visibility.

    11772 S Highway 17 Byp, Murrells Inlet, SC 29576
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    New Flex Development in Murrells
    $3,000 / Mo
    1,625 SF

    New Flex Development in Murrells

    New construction flex space with build-to-suit options available.

    4960 Highway 17, Murrells Inlet, SC 29576
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    Office or Retail Space Available
    $1,300 / Mo
    800 SF

    Office or Retail Space Available

    800 sq ft space suitable for office or retail.

    9898 Merry Ln, Murrells Inlet, SC 29576
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    Retail Space in Little River
    $1,931 / Mo
    1,159 SF

    Retail Space in Little River

    Retail space available in high-traffic Little River location.

    4390 Spa Dr, Little River, SC 29566
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    Retail Space in Little River
    $3,333 / Mo
    2,000 SF

    Retail Space in Little River

    Retail space available in high-traffic Little River shopping center.

    4390 Spa Dr, Little River, SC 29566
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    Retail Space in Little River
    $3,333 / Mo
    2,000 SF

    Retail Space in Little River

    Retail space available in high-traffic Little River location.

    4390 Spa Dr, Little River, SC 29566
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    Retail Center Renovation in Little River
    $1,913 / Mo
    1,148 SF

    Retail Center Renovation in Little River

    Retail and office spaces available in renovated Little River center.

    4390 Spa Dr, Little River, SC 29566
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    Versatile Commercial Space in Murrells
    $3,300 / Mo
    1,800 SF

    Versatile Commercial Space in Murrells

    1,800 sq ft commercial space suitable for retail/office.

    11871 Plaza Dr, Murrells Inlet, SC 29576
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    Professional Office Building in Myrtle Beach
    $5,000 / Mo
    2,230 SF

    Professional Office Building in Myrtle Beach

    Well-maintained office building in the heart of Myrtle Beach.

    607 19Th Ave N, Myrtle Beach, SC 29577
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    Myrtle Beach Office Space Available
    $1,000 / Mo
    780 SF

    Myrtle Beach Office Space Available

    Office space for lease in central Myrtle Beach location.

    1803 N Oak St, Myrtle Beach, SC 29577
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    North Myrtle Beach Retail Space
    $4,800 / Mo
    3,000 SF

    North Myrtle Beach Retail Space

    Commercial retail or office space in North Myrtle Beach.

    404-A Main St, North Myrtle Beach, SC 29582
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    Prime Second-Floor Office Space
    $2,080 / Mo
    2,080 SF

    Prime Second-Floor Office Space

    Spacious 2,080 sq ft office suite for lease.

    4221 N Kings Hwy, Myrtle Beach, SC 29577
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    Executive Office Space in Surfside
    $350 / Mo
    100 SF

    Executive Office Space in Surfside

    Well-appointed office space with included utilities and amenities.

    1500 Business St, Surfside Beach, SC 29575
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    High Visibility Retail Space Available
    $1,950 / Mo
    1,250 SF

    High Visibility Retail Space Available

    Retail space in high-traffic area, ready for your business.

    12270 Highway 17 Byp, Murrells Inlet, SC 29576
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    Prime Retail Space in Myrtle Beach
    $2,250 / Mo
    1,350 SF

    Prime Retail Space in Myrtle Beach

    High-visibility commercial unit in Northgate Plaza, Myrtle Beach.

    3566 Northgate Blvd, Myrtle Beach, SC 29588
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    Myrtle Beach Office and Warehouse
    $5,000 / Mo
    6,000 SF

    Myrtle Beach Office and Warehouse

    6,000 SF office and warehouse space with versatile layout.

    106 Lichen Ct, Myrtle Beach, SC 29588
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    Horry County, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Horry County, SC with 655 listings featured on our commercial real estate exchange. The current inventory includes 69,709,686,518 square feet of properties with an estimated lease value of $1,998 /Mo.

    Estimated lease rates for Commercial real estate in Horry County, SC begin at $0.78 SF/Yr, with an average of $19 SF/Yr and extend to $83 SF/Yr.
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