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    Portsmouth, NH
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    Portsmouth, NH Commercial Real Estate for Lease

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    Greenland, NH Newington, NH North Hampton, NH
    Showing 24 of 95 listings
    Downtown Office Suites Above Restaurants
    $3,000/Mo
    1,302 SF
    Downtown Office Suites Above Restaurants

    Three recently renovated office suites above The Friendly Toast and La Maison Navarre, with flexible layouts and abundant natural light.

    209-10 Vaughan Mall, Portsmouth, NH 3801

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    Second-Floor Office Suite
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    Second-Floor Office Suite

    Second-floor office overlooking Market Square in a CD5-zoned Portsmouth location.

    26 Market Square, Portsmouth, NH 03801

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    High-Traffic Retail Site
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    High-Traffic Retail Site

    7,000 SF retail space with 42 dedicated parking spaces along a high-visibility Portsmouth corridor for a range of storefront uses.

    2299 Lafayette Road, Portsmouth, NH 03801

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    Shared Office Suite with Waiting Area
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    Shared Office Suite with Waiting Area

    Shared office suite with kitchenette, waiting area, and a shared restroom with shower, suited for medical or general office use.

    1 Greenleaf Woods Drive, Portsmouth, NH 03801

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    Shared Office Suite with Shower
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    Shared Office Suite with Shower

    Shared office suite with restroom/shower access, kitchenette, and waiting area in a central Portsmouth setting.

    1 Greenleaf Woods Drive, Portsmouth, NH 03801

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    Shared Medical Office Suite
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    Shared Medical Office Suite

    Shared office suite with a waiting area and shared restroom with shower, kitchenette, and central access to major routes.

    1 Greenleaf Woods Drive, Portsmouth, NH 03801

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    Downtown Third-Floor Office Suite
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    Downtown Third-Floor Office Suite

    Third-floor walk-up office suite with heat, electric, and common-area cleaning included, plus parking and a kitchenette.

    159 Middle Street, Portsmouth, NH 03801

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    Two-Story Office Building
    $10 SF/Yr
    8,202 SF
    Two-Story Office Building

    Two-floor office layout with multiple private offices and an unfinished second level for expansion or storage.

    500 Maplewood Ave, Portsmouth, NH 03801

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    Downtown Office Suites For Lease
    $20 SF/Yr
    Downtown Office Suites For Lease

    Two move-in ready office suites with efficient layouts and excellent natural light in Downtown Portsmouth.

    25 Chestnut St AKA 82-86 Congress Street, Portsmouth, NH 3801

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    Office/Retail Space Near Daniel Street
    $3,500/Mo
    Office/Retail Space Near Daniel Street

    Office or retail space located just off Daniel Street.

    21A Daniel St, Portsmouth, NH 3801

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    Portsmouth Commercial Space For Lease
    $11 SF/Yr
    3,921 SF
    Portsmouth Commercial Space For Lease

    Commercial space with overhead doors, near Interstate 95.

    500 Maplewood Ave, Portsmouth, NH 03801

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    First-Class Office Space Available
    $16 SF/Yr
    5,257 SF
    First-Class Office Space Available

    First-class office space with panoramic views and central location.

    15 Rye St, Portsmouth, NH

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    Street-Level Retail Space with Parking
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    Street-Level Retail Space with Parking

    Street-level storefront with an open retail layout and on-site parking, suited for retail, boutique, studio, or service use.

    821 Islington Street, Portsmouth, NH 03801

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    Unique Office Space Overlooking Square
    $3,500/Mo
    Unique Office Space Overlooking Square

    Second-floor office space with views of Market Square.

    26 Market Sq 2, Portsmouth, NH 3801

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    Modern Office Space Available
    $24 SF/Yr
    3,679 SF
    Modern Office Space Available

    Contemporary office space in premier business corridor, available April 2026.

    75 Portsmouth Blvd, Portsmouth, NH

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    Renovated Office Suites Above Retail
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    Renovated Office Suites Above Retail

    Three recently renovated office suites above active street-level tenants, with flexible layouts and potential to combine spaces.

    10 Vaughan, Portsmouth, NH 03801

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    Downtown Office Suites Above Retail
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    Downtown Office Suites Above Retail

    Three recently renovated office suites with high ceilings and flexible layouts are available above street-level retail.

    10 Vaughan, Portsmouth, NH 03801

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    Single Room Office For Rent
    $350/Mo
    Single Room Office For Rent

    Single room office space available in Portsmouth, NH.

    6-i-170 West Rd, Portsmouth, NH 3801

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    Renovated Downtown Office Suites
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    Renovated Downtown Office Suites

    Move-in-ready suites with flexible layouts are available above popular downtown restaurants in Portsmouth, with some units offering kitchen amenities.

    10 Vaughan, Portsmouth, NH 03801

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    Office or Medical Office Space
    $16 SF/Yr
    2,027 SF
    Office or Medical Office Space

    Office or medical space in Portsmouth's Pease Tradeport.

    14 Manchester Square, Portsmouth, NH

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    Iconic Restaurant Location in Portsmouth
    $19 SF/Yr
    Iconic Restaurant Location in Portsmouth

    Prime downtown restaurant space in a former bank building.

    22 Market Sq 1, Portsmouth, NH 3801

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    Office/Retail Space Off Walkway
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    Office/Retail Space Off Walkway

    Mixed office and retail space available near Buckley’s Market for professional storefront or services use.

    21A Daniel Street, Portsmouth, NH 03801

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    Retail Space in Heritage Commons
    $22 SF/Yr
    1,950 SF
    Retail Space in Heritage Commons

    Retail space available in Portsmouth's Heritage Commons shopping center.

    2800 Lafayette Rd, Portsmouth, NH

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    High-End Office Space Available
    $40 SF/Yr
    10,524 SF
    High-End Office Space Available

    Office space with river views in desirable Portsmouth location.

    1 Harbour Place, Portsmouth, NH

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