Lee County, FL Storefront properties for sale

Historic Sanibel Building in Prime Location

$1,500,000

0.43 Acres

Historic Sanibel Building in Prime Location

520 Tarpon Bay Rd, Sanibel, FL 33957

Iconic Sanibel building, reimagined for modern use in high-traffic location.

Prime, high‑traffic location directly across from the upcoming Bailey's Shopping Plaza and adjacent to Doc Ford's Rum Bar & Grille.
Flexible Town Center General zoning allows for a wide range of commercial or creative uses.
Historic building (built in 1913) with a rich past, offering a unique and iconic presence on Sanibel Island.
Fully remediated and modernized structure with recent upgrades including new roof, HVAC, plumbing, electrical, flooring, and more.
Freestanding building offering high visibility and accessibility.

Updated: Dec 10, 2025

View details

Historic Matlacha Corner Retail Opportunity

Pending

$599,900

0.11 Acres

Historic Matlacha Corner Retail Opportunity

4573 Pine Island Rd NW, Matlacha, FL 33993

High-traffic corner property in historic Matlacha, ideal for retail.

High‑traffic corner location in the heart of historic Matlacha.
Direct canal access to Matlacha Pass.
Established business location with a successful 7+ year history as a retail and wholesale seafood market.
Includes both the land and building.
New roof (2023) and structural reinforcements (2024).

Updated: Dec 1, 2025

View details

$699,900

0.50 Acres

Fort Myers Commercial Building For Sale

2,964 sq ft commercial building on high-traffic MLK corridor.

3050 Michigan Ave, Fort Myers, FL 33916

View details

Sanibel Island Income-Producing Commercial Property

$5,400,000

0.84 Acres

Sanibel Island Income-Producing Commercial Property

Income-producing commercial property on Sanibel Island with high visibility.

1039 Periwinkle Way, Sanibel, FL 33957

View details

$48,900

Established Salon in Winn Dixie Center

Well-established beauty salon in a convenient location.

9848 Stringfellow Rd, St James City, FL 33956

View details

Remodeled Commercial Property in Matlacha

$1,485,000

0.30 Acres

Remodeled Commercial Property in Matlacha

Remodeled commercial property with high visibility and accessibility in Matlacha.

4574 Pine Island Rd NW, Matlacha, FL 33993

View details

Pine Island Commercial Building For Sale

Pending

$749,000

0.69 Acres

Pine Island Commercial Building For Sale

2100 SqFt commercial building in Pine Island Center.

10493 Stringfellow Rd, Saint James City, FL 33956

View details

$374,999

0.50 Acres

Established Print and Graphics Company

Turn-key print and graphics company for sale in Cape Coral.

229 Del Prado Blvd N, Cape Coral, FL 33909

View details

$1,195,000

0.14 Acres

Cape Coral Retail Building For Sale

Turnkey retail building in downtown Cape Coral with high traffic.

1220 Lafayette St, Cape Coral, FL 33904

View details

$7,300,000

0.32 Acres

Waterfront Property with Liquor License

Waterfront property on Fort Myers Beach with direct access.

1167 Estero Blvd, Fort Myers Beach, FL 33931

View details

$49,950

0.24 Acres

Lehigh Acres Commercial Opportunity

Commercial property suitable for retail or office in Lehigh Acres.

838 Burns Ave S, Lehigh Acres, FL 33974

View details

$6,885,471

5,598 SF

Harbour Point Waterfront Retail

Prime FL waterfront retail investment.

17501 Harbour Pointe Dr, Fort Myers, FL 33908

View details

$5,950,000

24,900 SF

Fort Myers Mixed-Use Investment

24-unit multifamily, retail complex, high ROI.

2741 1St St, Fort Myers, FL 33916

View details

$275,000

Bonita Beach Road Condo

First-floor condo with high visibility on Bonita Beach Road.

10915 Bonita Beach Rd SE 115A, Bonita Springs, FL 34135

View details

$3,250,000

Honey Bee Farm Opportunity

Profitable honey bee farm with retail and production facilities.

17131 Slater Rd, Fort Myers, FL 33917

View details

$3,300,000

Retail Building on US 41

Retail building with two entrances on US 41.

4805 S Cleveland Ave, Fort Myers, FL 33907

View details

$3,000,000

3,218 SF

Retail Property on US 41

Retail property with frontage on US 41 in Fort Myers.

12300 S Cleveland Ave, Fort Myers, FL 33907

View details

$2,550,000

3,720 SF

1.62 Acre Redevelopment Site

1.62 acre hard corner site ideal for redevelopment.

19630-19650 S Tamiami Trl, Fort Myers, FL 33908

View details

$899,000

6,370 SF

Downtown Fort Myers Retail Property

Retail property with high visibility in downtown Fort Myers.

2400 Cleveland Ave, Fort Myers, FL 33901

View details

$1,590,000

5,596 SF

Visible Daycare Facility on US41

Highly visible daycare facility in Estero, Lee County, Florida.

19660 S Tamiami Trl, Fort Myers, FL 33908

View details

$2,300,000

1 SF

Lehigh Acres Retail Building ForSale

Freestanding retail building with drive-thru on 0.76 acres.

800 Leonard Blvd N | Lehigh Acres, Lehigh Acres, FL 33971

View details

$1,200,000

7,245 SF

Retail Property Available For Sale

Retail property for sale or lease in Lehigh Acres, FL.

270 Beth Stacey Blvd, Lehigh Acres, FL 33936

View details

Explore Off-Market Properties in Lee County, FL

Consider similar Off-Market properties in Lee County, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

17501 Harbour Pointe Dr

Individual retail properties • 5,598 SF

Value Estimation by Request

17501 Harbour Pointe Dr, Fort Myers, FL 33908

View details

2741 1St St

Individual retail properties • 24,900 SF

Value Estimation by Request

2741 1St St, Fort Myers, FL 33916

View details

Lee County, FL Storefront Properties Investment Opportunities Market Analysis

Explore 30 storefront properties for sale in Lee County, FL, showcased through 22 active listings on our real estate platform. These investment opportunities span a total of 336,231 square feet of properties for sale, with an estimated market value of $32,189,220.

Prices for retail units in Lee County, FL start at $49,950, averaging $2,682,435, and reaching up to $7,300,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

Lee County, FL Storefront Properties for Sale

Historic Sanibel Building in Prime Location

Iconic Sanibel building, reimagined for modern use in high-traffic location.