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    Cape Girardeau County, MO Shopping Centers for Lease

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    Saint Louis, MO Kansas City, MO Springfield, MO
    6 results
    Retail Space Near Interstate 55
    Contact for pricing
    10,800 SF

    Retail Space Near Interstate 55

    258 Siemers Dr, Cape Girardeau, MO

    Retail space in regional shopping hub with interstate access.

    • 200,000 SF power center
    • Adjacent to Interstate 55
    • Regional shopping hub for southeastern Missouri
    • Excellent co‑tenancy
    • Easy Interstate access
    Updated: Aug 18, 2025
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    Retail Space Near St. Francis
    Contact for pricing
    3,154 SF

    Retail Space Near St. Francis

    3049 Williams St, Cape Girardeau, MO

    Retail space available across from St. Francis Medical Center.

    • Nearly half a million square feet of retail shopping in the project
    • New national anchors are coming to the project
    • Across the street from St. Francis Medical Center
    • Highly visible and accessible to William Street
    • William St - 33,286 VPD
    Updated: May 6, 2024
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    Regional Shopping Center Near I-55
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    9,400 SF

    Regional Shopping Center Near I-55

    Regional shopping center with easy access to Interstate 55.

    155-157 Siemers Dr, Cape Girardeau, MO
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    Retail Space Near West Park
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    7,908 SF

    Retail Space Near West Park

    Retail space in regional shopping hub with easy Interstate access.

    3047 William St, Cape Girardeau, MO
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    Retail Space Near West Park
    Contact for pricing
    4,970 SF

    Retail Space Near West Park

    Retail space in regional shopping hub with high visibility.

    3036-3048 William St, Cape Girardeau, MO
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    Retail Space Near West Park
    Contact for pricing
    1,595 SF

    Retail Space Near West Park

    Retail space available in regional shopping hub near West Park.

    240-250 S Silver Springs Rd, Cape Girardeau, MO
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    Based on your search, we've compiled 10 Potential Opportunities for your consideration.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Ellijay, GA Commercial Land
    $17,424/Mo

    Ellijay, GA Commercial Land

    12.86 acres of commercial land for lease in Ellijay.

    12.86AC Highlands Hill Drive, Ellijay, GA 30540
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    Commercial Land in Retail Hub
    $5,000/Mo

    Commercial Land in Retail Hub

    2.67-acre commercial lot in high-traffic area, Cambridge, OH.

    Southgate Road, Cambridge, OH 43725
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    Rayzor Ranch Ground Lease Opportunity
    Contact for pricing

    Rayzor Ranch Ground Lease Opportunity

    Ground lease opportunity in Rayzor Ranch Mixed Use Development.

    I-35 & West University Dr. |, Denton, TX 76201
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    Prime Corner Land for Lease
    $22,000 SF/Yr

    Prime Corner Land for Lease

    1.5-acre corner lot near I-20 and new shopping centers.

    406 Center Point Road, Weatherford, TX 76087
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    Cape Girardeau County, MO Shopping centers Leasing Opportunities Market Analysis

    Explore Shopping centers leasing options in Cape Girardeau County, MO with 6 listings featured on our commercial real estate exchange. The current inventory includes 37,827 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Shopping centers in Cape Girardeau County, MO begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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