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    Sikeston, MO Retail Properties & Spaces for Lease

    6 results
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    Sikeston Office Suite For Rent
    $3,625 / Mo
    2,000 SF

    Sikeston Office Suite For Rent

    912 S Main St, Sikeston, MO 63801

    Recently-built office suite with four offices, bathroom, and kitchenette.

    • High visibility location on Sikeston's busiest corridor.
    • Ready for immediate occupancy with 4 finished offices.
    • Two entrances ideal for businesses with public traffic.
    • Includes a bathroom and kitchenette with refrigerator and table/chairs.
    • Located in a recently‑built (2020) strip center.
    Updated: Sep 22, 2025
    View details
    Professional Space Near Main Intersection
    $1,000 / Mo

    Professional Space Near Main Intersection

    1226 Linn St, Sikeston, MO 63801

    Prime location, high visibility, and flexible floor plan.

    • Prime location near the main intersection of town, offering high visibility.
    • Ample parking for employees and visitors.
    • Flexible floor plan suitable for various business types (office, studio, showroom).
    • Convenient access to major highways for easy commuting.
    • Professional atmosphere creating a welcoming environment.
    View details
    New Office/Retail Center on Main
    $1,950 / Mo

    New Office/Retail Center on Main

    Prime location with excellent traffic and visibility.

    600 N Main St, Sikeston, MO 63801
    View details
    Professional Space Near Main Intersection
    $2,000 / Mo

    Professional Space Near Main Intersection

    Prime location, high visibility, and flexible floor plan.

    1226 Linn St, Sikeston, MO 63801
    View details
    Retail Space in Sikeston, MO
    Contact for pricing
    2,900 SF

    Retail Space in Sikeston, MO

    Retail space available in grocery store anchored shopping center.

    925-1077 Malone Ave, Sikeston, MO 63801
    View details
    Sikeston Commercial Land Opportunity
    Contact for pricing
    215,186 SF

    Sikeston Commercial Land Opportunity

    Prime Southeast Missouri Outlot

    1330 Main St, Sikeston, MO 63801
    View details
    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 6 Active listings in Sikeston, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 10 Properties for Sales.

    Explore Retail properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Charleston Retail Space - Main Street
    Contact for pricing
    8,351 SF

    Charleston Retail Space - Main Street

    High-traffic retail space, 8,351 sq ft.

    601 Main St, Charleston, MO 63834
    View details
    Charleston Retail or Office Space
    Contact for pricing

    Charleston Retail or Office Space

    Retail or office space with excellent visibility and parking.

    114 W Commercial St, Charleston, MO 63834
    View details
    Retail Space Near Interstate 55
    Contact for pricing
    10,800 SF

    Retail Space Near Interstate 55

    Retail space in regional shopping hub with interstate access.

    258 Siemers Dr, Cape Girardeau, MO 63701
    View details
    West Park Mall Medical Office Space
    Contact for pricing
    79,122 SF

    West Park Mall Medical Office Space

    Missouri medical office suites for lease

    3049 William St, Cape Girardeau, MO 63703
    View details

    Explore Similar Spaces for Sale in Sikeston, MO

    Consider Similar Space for Sale. We found 10 Spaces in Nearby Locations matching your search parameters.

    Sikeston Commercial Property For Sale
    $650,000
    1.28 Acres

    Sikeston Commercial Property For Sale

    Prime commercial location with high visibility and established business history.

    1105 S Main St, Sikeston, MO 63801
    View details
    Sikeston Car Wash with Expansion Potential
    $1,000,000
    40,511 SF

    Sikeston Car Wash with Expansion Potential

    Turnkey car wash with expansion potential in high-demand market.

    531 N Main St, Sikeston, MO 63780
    View details
    Sikeston Commercial Property with Income
    $290,000
    4,244 SF

    Sikeston Commercial Property with Income

    Commercial building, duplex, and storage on 1.22 acres.

    101-103 Donald Fulton Dr, Sikeston, MO 63801
    View details
    Sikeston Commercial Property For Sale
    $600,000
    1.30 Acres

    Sikeston Commercial Property For Sale

    Income-producing property with commercial spaces and storage units.

    2008 N Main St, Sikeston, MO 63801
    View details
    Historical Building in Downtown Sikeston
    $269,000
    6,321 SF

    Historical Building in Downtown Sikeston

    Two-story historic building in downtown Sikeston, ideal for investors.

    112 Front St, Sikeston, MO 63801
    View details
    Sikeston Carwash with High Visibility
    $1,250,000
    40,946 SF

    Sikeston Carwash with High Visibility

    Turnkey carwash with high traffic, visibility, and recurring revenue.

    900 S Main St, Sikeston, MO 63801
    View details
    Sikeston Retail Property For Sale
    $550,000
    1,150 SF

    Sikeston Retail Property For Sale

    Established family-owned business with high visibility for over 30 years.

    1018 Linn St, Sikeston, MO 63801
    View details
    Sikeston Commercial Building Investment Opportunity
    $979,500

    Sikeston Commercial Building Investment Opportunity

    High-visibility commercial building with income and upside potential.

    808 E Wakefield Ave, Sikeston, MO 63801
    View details
    Neighborhood Center with Established Businesses
    Contact for pricing

    Neighborhood Center with Established Businesses

    Neighborhood center with high traffic, visibility, and established businesses.

    1100 S Main St, Sikeston, MO 63801
    View details
    Historic Downtown Sikeston Retail Opportunity
    $275,000
    14,642 SF

    Historic Downtown Sikeston Retail Opportunity

    Two-story retail space in high-traffic downtown Sikeston.

    124 E Front St, Sikeston, MO 63801
    View details

    Sikeston, MO Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in Sikeston, MO with 16 listings featured on our commercial real estate exchange. The current inventory includes 87,120,000 square feet of properties with an estimated lease value of $21 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in Sikeston, MO begin at $21 SF/Yr, with an average of $21 SF/Yr and extend to $21 SF/Yr.
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    Popular Searches in Sikeston, MO

    Most Searched ZIP Codes in Sikeston, MO

    • 63801

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