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    Cape Girardeau, MO Retail Properties for Lease

    10 results
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    Renovated Commercial Space For Lease
    $2,500 / Mo
    2,937 SF

    Renovated Commercial Space For Lease

    230 N Sprigg St, Cape Girardeau, MO 63701

    Renovated commercial space with high visibility in a prime location.

    • Prime location with high traffic and road frontage on N Sprigg St, offering excellent visibility in the Business District.
    • Almost 3000 sq ft of renovated space suitable for multiple offices or service providers.
    • Completely renovated with brand new A/C, roof, gutters, flooring, fixtures, bathrooms, kitchenette, and siding.
    • Significant rental income potential.
    • Located downtown, in the midst of exciting activities.
    Updated: Jun 30, 2025
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    West Park Mall Medical Office Space
    Contact for pricing
    79,122 SF

    West Park Mall Medical Office Space

    3049 William St, Cape Girardeau, MO 63703

    Missouri medical office suites for lease

    • West Park Mall, 3049 William St, Cape Girardeau, MO, offers 79,122 SF of medical office space for lease; 22 suites available, ranging from 1,002 SF to 24,221 SF contiguous.
    • Located directly across from St. Francis Medical Center.
    • High visibility and accessibility from William Street (21,647 VPD).
    • Part of a large retail development with nearly half a million square feet of retail space and new national anchors coming soon.
    Updated: Dec 11, 2024
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    West Park Strip Center Retail Space
    Contact for pricing
    23,464 SF

    West Park Strip Center Retail Space

    High-traffic retail center; two spaces available.

    250 Silver Springs Rd, Cape Girardeau, MO 63703
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    Lambert Plaza Retail Space
    Contact for pricing
    46,692 SF

    Lambert Plaza Retail Space

    Cape Girardeau, MO Retail Opportunity

    155 Siemers Dr, Cape Girardeau, MO 63701
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    Retail Space Near West Park
    Contact for pricing
    7,908 SF

    Retail Space Near West Park

    Retail space in regional shopping hub with easy Interstate access.

    3047 William St, Cape Girardeau, MO 63703
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    Retail Space Near Interstate 55
    Contact for pricing
    10,800 SF

    Retail Space Near Interstate 55

    Retail space in regional shopping hub with interstate access.

    258 Siemers Dr, Cape Girardeau, MO 63701
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    Retail Space Near West Park
    Contact for pricing
    4,970 SF

    Retail Space Near West Park

    Retail space in regional shopping hub with high visibility.

    3036-3048 William St, Cape Girardeau, MO 63703
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    Regional Shopping Center Near I-55
    Contact for pricing
    9,400 SF

    Regional Shopping Center Near I-55

    Regional shopping center with easy access to Interstate 55.

    155-157 Siemers Dr, Cape Girardeau, MO 63701
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    Retail Space Near St. Francis
    Contact for pricing
    3,154 SF

    Retail Space Near St. Francis

    Retail space available across from St. Francis Medical Center.

    3049 Williams St, Cape Girardeau, MO
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    Retail Space Near West Park
    Contact for pricing
    1,595 SF

    Retail Space Near West Park

    Retail space available in regional shopping hub near West Park.

    240-250 S Silver Springs Rd, Cape Girardeau, MO 63703
    View details
    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 10 Active listings in Cape Girardeau, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

    Explore Retail properties for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail Space in High-Traffic Location
    $1,440 / Mo

    Retail Space in High-Traffic Location

    Retail space with signage, parking, and delivery entrance available for lease.

    2931 E Jackson Blvd, Jackson, MO 63755
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    Retail Space in High Traffic Area
    $1,440 / Mo
    34,761 SF

    Retail Space in High Traffic Area

    Retail space in Jackson, MO with high visibility.

    2931 E Jackson Blvd, Jackson, MO 63755
    View details
    Charleston Retail or Office Space
    Contact for pricing

    Charleston Retail or Office Space

    Retail or office space with excellent visibility and parking.

    114 W Commercial St, Charleston, MO 63834
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    Charleston Retail Space - Main Street
    Contact for pricing
    8,351 SF

    Charleston Retail Space - Main Street

    High-traffic retail space, 8,351 sq ft.

    601 Main St, Charleston, MO 63834
    View details

    Explore Similar Spaces for Sale in Cape Girardeau, MO

    Consider Similar Space for Sale. We found 9 Spaces in Nearby Locations matching your search parameters.

    Versatile Commercial Space in Missouri
    $900,000
    7,396 SF

    Versatile Commercial Space in Missouri

    7,396 SF commercial building with banquet, dining, and bar areas.

    20 N Spanish St, Cape Girardeau, MO 63701
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    Broadway Commercial Space with Apartment
    $280,000
    5,100 SF

    Broadway Commercial Space with Apartment

    Versatile investment opportunity with remodeled apartment and commercial space.

    520 Broadway St, Cape Girardeau, MO 63701
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    Versatile Riverfront Commercial Property
    $475,000
    7,044 SF

    Versatile Riverfront Commercial Property

    Flexible commercial space with riverfront location and development potential.

    308 N Main St, Cape Girardeau, MO 63701
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    Versatile Commercial Property For Sale
    $295,000
    2,920 SF

    Versatile Commercial Property For Sale

    High-visibility commercial property with flexible layout and spacious attached warehouse.

    225 Clark Ave, Cape Girardeau, MO 63701
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    Versatile Riverfront Commercial Property
    $400,000
    4,400 SF

    Versatile Riverfront Commercial Property

    Prime riverfront property suitable for office, restaurant, warehouse, or mixed-use.

    450 N Main St, Cape Girardeau, MO 63701
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    Renovated Commercial Space in Cape Girardeau
    $239,900
    2,937 SF

    Renovated Commercial Space in Cape Girardeau

    Renovated commercial space with high potential in a prime location.

    230 N Sprigg St, Cape Girardeau, MO 63701
    View details
    Versatile Commercial Building in Cape
    $225,000
    0.57 Acres

    Versatile Commercial Building in Cape

    Adaptable 1800 sq ft commercial building in thriving Cape Girardeau.

    2357 Rust Ave, Cape Girardeau, MO 63703
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    Freestanding Restaurant in Cape Girardeau
    $1,950,000
    5,396 SF

    Freestanding Restaurant in Cape Girardeau

    Single-tenant restaurant with a new long-term lease.

    202 S Broadview St, Cape Girardeau, MO 63703
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    Applebee's Net Lease Investment
    $1,875,000
    5,396 SF

    Applebee's Net Lease Investment

    Missouri Applebee's: 8% Cap Rate, NNN Lease

    202 Broadview St, Cape Girardeau, MO 63703
    View details

    Cape Girardeau, MO Retail properties Leasing Opportunities Market Analysis

    Explore Retail properties leasing options in Cape Girardeau, MO with 19 listings featured on our commercial real estate exchange. The current inventory includes 127,935,720 square feet of properties with an estimated lease value of $10 SF/Yr.

    Estimated lease rates for Retail properties in Cape Girardeau, MO begin at $10 SF/Yr, with an average of $10 SF/Yr and extend to $10 SF/Yr.
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    Browse Retail properties for Lease Near Cape Girardeau, MO

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    Most Searched ZIP Codes in Cape Girardeau, MO

    • 63703
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