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    Durham, NC Office Units for Lease

    32 results
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    Versatile Office/Medical Space Available
    $3,000 / Mo
    2,400 SF

    Versatile Office/Medical Space Available

    3925 N Duke St, Durham, NC 27704

    2400 sq ft office/medical suite in prime Durham location.

    • Prime Durham location, minutes from downtown and Duke Regional Hospital.
    • Versatile 2400 sq ft space suitable for office, medical, or service‑based businesses.
    • Five private offices plus open central workspace.
    • Previously configured for dental and salon use.
    • Large reception area ideal for client‑facing businesses.
    Updated: Feb 18
    View details
    Durham Office Condo For Lease
    $1,500 / Mo
    478 SF

    Durham Office Condo For Lease

    3201 Yorktown Ave, Durham, NC 27713

    Recently remodeled office condo with easy access and great location.

    • Recently remodeled with new paint, flooring, ceilings, light fixtures, updated bathroom and kitchenette, and new HVAC system
    • Easy access from parking lot
    • Convenient location: Minutes to Hwy 40 and 885
    • Proximity to Amenities: 2 Miles to Lowes Shopping Plaza, 4 Miles to RTP, 5 Miles to Southpoint Mall and Downtown Durham
    • Includes a brand new refrigerator
    Updated: Feb 10
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    Office Space Near Universities
    $1,995 / Mo
    1,000 SF

    Office Space Near Universities

    Office space in Durham, close to amenities and universities.

    1804 Martin Luther King Junior Pkwy, Durham, NC 27707
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    Office Condo in Durham's Office Park
    $3,500 / Mo
    2,000 SF

    Office Condo in Durham's Office Park

    Office condominium with private entrance in a convenient location.

    6 Consultant Pl, Durham, NC 27707
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    Durham Office Space For Lease
    $45,045
    2,145 SF

    Durham Office Space For Lease

    Flexible office unit with ample parking and recent upgrades.

    1906 A, Durham, NC 27713
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    Office Suite with Private Offices
    $36,000
    1,760 SF

    Office Suite with Private Offices

    Office suite featuring multiple private office spaces for rent.

    5315 Highgate Dr, Durham, NC 27713
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    Prime Medical Office Space Available
    Pending
    $18 SF/Yr
    2,312 SF

    Prime Medical Office Space Available

    Versatile medical/office space in Durham's thriving North Duke corridor.

    2609 N Duke St Unit Bldg 300, Durham, NC 27704
    View details
    Professional Office Condos For Lease
    $2,400 / Mo
    5,120 SF

    Professional Office Condos For Lease

    Office condos for lease near Duke University Medical Center.

    2741 Campus Walk Ave, Durham, NC 27705
    View details
    Roxboro Road Professional Office Space
    $20 SF/Yr
    2,408 SF

    Roxboro Road Professional Office Space

    Office space ideal for professional services and medical offices.

    4210 N Roxboro St, Durham, NC 27704
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    Downtown Durham Office Space Available
    Contact for pricing
    16,692 SF

    Downtown Durham Office Space Available

    Office spaces for lease in the heart of downtown Durham.

    433 W Main St, Durham, NC 27701
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    Plug and Play Lab Space
    $30 SF/Yr
    94,603 SF

    Plug and Play Lab Space

    Move-in ready lab and office space in Durham, NC.

    4025 Stirrup Creek Dr, Durham, NC 27703
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    Durham Medical/Office Building for Lease
    $23 SF/Yr
    4,769 SF

    Durham Medical/Office Building for Lease

    Freestanding 4,769 SF building suitable for medical or office use.

    110 E Carver St, Durham, NC 27704
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    Downtown Durham Office Space
    Contact for pricing
    41,000 SF

    Downtown Durham Office Space

    Full floor office space in downtown Durham's iconic tower.

    212 West Main St, Durham, NC 27701
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    Office/Medical Building Near Southpoint Mall
    $26 SF/Yr
    18,395 SF

    Office/Medical Building Near Southpoint Mall

    Single-story office/medical building near Southpoint Mall available for lease.

    5501 Fortunes Ridge Dr, Durham, NC 27713
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    Downtown Durham Office Space Available
    $29 SF/Yr
    32,522 SF

    Downtown Durham Office Space Available

    Move-in ready office space in downtown Durham with modern amenities.

    505 S Duke St, Durham, NC 27701
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    Office Space Near University Hill
    Contact for pricing
    12,500 SF

    Office Space Near University Hill

    Office space with high visibility, convenience, and walkability.

    3917 University Dr, Durham, NC 27707
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    Durham Flex Space Available
    $13 SF/Yr
    35,000 SF

    Durham Flex Space Available

    35,000 SF flex space for rent in Durham.

    4808 Chin Page Rd, Durham, NC 27703
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    Renovated Historic Building on Ninth
    Contact for pricing
    8,400 SF

    Renovated Historic Building on Ninth

    Fully renovated historic building in Durham's vibrant 9th Street district.

    706 Ninth St, Durham, NC 27705
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    Downtown Durham Historic Buildings
    $26 SF/Yr
    35,378 SF

    Downtown Durham Historic Buildings

    Historic buildings in downtown Durham with retail and office spaces.

    102 City Hall Plz, Durham, NC 27701
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    Durham Office Space For Rent
    Contact for pricing
    69,020 SF

    Durham Office Space For Rent

    Office space with easy access to highways and airport.

    31 Alexandria Way, Durham, NC 27713
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    Luxury Mixed-Use Development Near Duke
    $25 SF/Yr
    118,000 SF

    Luxury Mixed-Use Development Near Duke

    Class A mixed-use development near Duke University and hospitals.

    2812 Erwin Rd, Durham, NC 27705
    View details
    Durham Flex Space For Rent
    Pending
    $4,500 / Mo
    1,233 SF

    Durham Flex Space For Rent

    Flex space with accessibility to the Greater Triangle Area.

    2528 S Alston Ave, Durham, NC 27713
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    Office/Clinic Space Near Shopping Centers
    $1,995 / Mo

    Office/Clinic Space Near Shopping Centers

    Office or clinic space in a convenient, accessible location.

    1804 Martin Luther King Pkwy, Durham, NC 27707
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    Downtown Durham Office Suites
    Contact for pricing
    18,968 SF

    Downtown Durham Office Suites

    Prime Office Space, 13,561 SF Available

    433 Main St, Durham, NC 27701
    View details

    Durham, NC Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Durham, NC with 43 listings featured on our commercial real estate exchange. The current inventory includes 26,289,331,200 square feet of properties with an estimated lease value of $472 /Mo.

    Estimated lease rates for Office Units in Durham, NC begin at $5 SF/Yr, with an average of $23 SF/Yr and extend to $43 SF/Yr.
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    Popular Searches in Durham, NC

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    Most Searched ZIP Codes in Durham, NC

    • 27701
    • 27713
    • 27703
    • 27704
    • 27707
    • 27705

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