Office Units

Port St Lucie, FL Office Units for Lease

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Port Saint Lucie, FL Vero Beach, FL Jensen Beach, FL Stuart, FL Palm City, FL
53 properties
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Second-Floor Office Unit
Gross
Second-Floor Office Unit

2011 S 25TH Street, Fort Pierce, FL 34947

$650/Mo
52–87 people  13,166 sqft  Built 1977  0.85 acres

Gross lease includes electricity, with a shared common-area restroom.

63 parking spaces
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Second-Floor Office Unit
Gross
Second-Floor Office Unit

2011 S 25TH Street, Fort Pierce, FL 34947

$850/Mo
52–87 people  13,166 sqft  Built 1977  0.85 acres

Gross-lease office suite with elevator access, central air, and electricity included.

20 parking spaces
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First-Floor Office Suite
Gross
First-Floor Office Suite

600 Citrus Avenue, Fort Pierce, FL 34950

$2,700/Mo
53–88 people  13,284 sqft  Built 2007  1 acre

Newly configured professional office space within a concrete building with central HVAC and public utilities.

44 parking spaces
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Flexible Retail Space
Flexible Retail Space

7202 S U.S. Hwy 1 #7214-7216, Port St Lucie, FL 34952

Retail space
$2,700/Mo
14,850 sqft  Built 1976

Adaptable commercial unit supports retail, office, or professional service operations with on-site parking.

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Retail Space
Retail Space

Port St Lucie, FL 34952

Retail space
$2,600/Mo
14,850 sqft  Built 1976

The unit has a flexible configuration for retail, office, or professional service use.

6 parking spaces
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Retail Suite with Open Layout
Retail Suite with Open Layout

Port St Lucie, FL 34986

Retail space
$3,500/Mo
1,300 sqft  Built 2007
Highway access

CG-zoned commercial space offers a private office, restroom, and adaptable setting for office, medical, wellness, retail, or professional services.

27 parking spaces  Open floor plan  Private office  Restroom
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Built-Out Medical Office Space
Triple net (NNN)
Built-Out Medical Office Space

Port St Lucie, FL 34952

Medical Office Space
$20 SF/Yr
11,187 sqft  Built 2000  1.02 acres

Five contiguous suites support single-tenant or multi-suite medical occupancy near a hospital campus.

49 parking spaces
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Medical Office Building with Five Suites
Triple net (NNN)
Medical Office Building with Five Suites

1405 SE Goldtree Dr, Port St Lucie, FL 34952

Medical Office Space
Contact for pricing
11,187 sqft  Built 2000

Built-out medical space offers contiguous occupancy or multiple suite configurations near a hospital and established medical campus.

49 parking spaces
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Industrial Flex Unit with Mezzanine
Modified gross
Industrial Flex Unit with Mezzanine

Port St Lucie, FL 34986

Flex space
$3,398/Mo
2,232 sqft  Built 2006

Air-conditioned offices complement a warehouse with high clear ceilings and ground-level roll-up loading access.

2 parking spaces
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Updated Marina-View Office Unit
Updated Marina-View Office Unit

2010 Harbortown W, Fort Pierce, FL 34946

$1,000/Mo
33–55 people  8,385 sqft  Built 1988  1.65 acres

Updated vinyl-floored office unit with central HVAC, marina views, and ample parking for tenants and clients.

20 parking spaces
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Second-Floor Office Unit
Gross
Second-Floor Office Unit

2011 S 25TH Street #207 / 209, Fort Pierce, FL 34947

$650/Mo
52–87 people  13,166 sqft  Built 1977

Gross lease includes electricity, with restroom access provided in a shared common area.

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Updated Office Units with ADA Restroom
Updated Office Units with ADA Restroom

2210 S 40th Street, Fort Pierce, FL 34947

$1,700/Mo
3–5 people  792 sqft  Built 1966  0.21 acres

Freestanding commercial space offers flexible work areas, a private office, lounge, and employee amenities.

5 parking spaces
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Multi-Office Commercial Suite
Modified gross
Multi-Office Commercial Suite

2222 Colonial Road, Fort Pierce, FL 34950

$17 SF/Yr
Built 1989  1.3 acres

Professional office layout with multiple private rooms, shared meeting space, reception, and kitchen facilities.

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Second-Floor Office Unit
Gross
Second-Floor Office Unit

2011 S 25TH Street #216, Fort Pierce, FL 34947

$850/Mo
52–87 people  13,166 sqft  Built 1977

Gross-lease office space with electricity included and access to shared common-area amenities.

63 parking spaces
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Three-Office Suite
Three-Office Suite

Port St Lucie, FL 34952

Class A
$1,645/Mo
1 space  940 sqft  0.02 acres  Floor 2
3 private offices  Highway access

Second-floor workspace offers three private offices, an open area, elevator access, and natural light.

Shared lobby restrooms
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Second-Floor Office Unit
Gross
Second-Floor Office Unit

2011 S 25TH Street 216, Fort Pierce, FL 34947

$850/Mo
2–3 people  546 sqft  Built 1977

Gross lease includes electricity, with internet, cable, and interior maintenance handled by the tenant.

63 parking spaces
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Storefront Space with Private Office
Storefront Space with Private Office

2017 Ave D, Fort Pierce, FL 34950

Storefront property
$1,400/Mo
1,406 sqft  Built 1945

Flexible interior includes a reception area, open work zone, and fenced backyard with grass and fruit trees.

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Second-Floor Office Unit
Gross
Second-Floor Office Unit

2011 S 25th St, Fort Pierce, FL 34947

$650/Mo
1–2 people  355 sqft  Built 1977

Compact office space with elevator access, shared common-area restroom, and electricity included under a gross lease.

63 parking spaces
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Versatile Facility for Lease
Versatile Facility for Lease

2525 S 25th St, Fort Pierce, FL 34981

Day care center
$5,000/Mo
4,028 sqft  Built 1997

4,028 SF building ideal for school or office use.

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Class A Office Suite
Gross
Class A Office Suite

600 Citrus Avenue, Fort Pierce, FL 34950

$2,700/Mo
5–9 people  1,476 sqft  Built 2007

Recently configured professional office space in a 2007-built building with substantial onsite and street parking.

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Industrial Flex Warehouse Unit
Industrial Flex Warehouse Unit

110-575 Nw Mercantile Pl, Port St Lucie, FL 34986

Flex space
$3,398/Mo
2,232 sqft

Industrial flex unit with air-conditioned office/showroom space, an enclosed mezzanine, and a 12-by-14 roll-up door.

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Updated Freestanding Office Building
Updated Freestanding Office Building

2210 S 40th Street, Fort Pierce, FL 34947

$1,700/Mo
3–5 people  792 sqft  Built 1966

Freestanding office building with impact windows, a metal roof, and flexible interior space for workstations plus private office.

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Office Unit with Elevator Access
Office Unit with Elevator Access

2100 SE Hillmoor Drive 204a, Port St Lucie, FL 34952

$2,287/Mo
3–6 people  940 sqft  Built 2008

Second-floor office suite with private offices, shared lobby restrooms, natural light, and on-site parking.

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Medical Office Condo with Exam Rooms
Medical Office Condo with Exam Rooms

1801 S 23rd Street 3, Fort Pierce, FL 34950

Medical Office Space
$3,179/Mo
1,734 sqft  Built 1988

Move-in-ready medical office condo with four exam rooms, offices, and dedicated lab or prep space.

50 parking spaces
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Port St Lucie, FL Office Units Lease Rates & Market Statistics

Browse 53 Office Units for lease in Port St Lucie, FL on Realmo, a commercial real estate marketplace serving the Port St Lucie area. The current inventory totals 275,519 square feet of properties — an average of ~5,200 SF per listing.

Office Units lease rates in Port St Lucie range from $1.37 SF/Yr at the entry level to $40 SF/Yr at the top of the market, averaging $17.78 SF/Yr. That's a 29x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $17.78 SF/Yr, the local average runs 51% below Florida's state average of $36.38 SF/Yr.

Within St. Lucie County, most Port St Lucie office units listings are located in and around Port Saint Lucie, with additional options across the city. Office Units make up 69% of the 77 Office Spaces currently for lease in Port St Lucie, with asking rates in line with the citywide Office Spaces average. Tenants comparing options may also consider Medical Office Space (21 listings) and Office buildings (10 listings) elsewhere in the Port St Lucie market.

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