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Pickens County, SC Office Properties & Spaces for Sale

7 results
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Unique Office Building Near Courthouse
$350,000
0.16 Acres

Unique Office Building Near Courthouse

113 Court St, Pickens, SC 29671

Commercial office building with two units and distinctive architectural features.

  • Prime commercial location next to the Pickens County Court House.
  • Two rental units provide additional income potential.
  • Unique architectural features: soaring wood ceilings, solid wood beams, brick accents, and a double brick fireplace.
  • Flexible floor plan with spacious meeting and conference rooms, kitchenette, and open work areas.
  • Private brick courtyard provides natural light and an appealing outdoor space.
Updated: Nov 25, 2025
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Multi-Tenant Investment Opportunity
$550,000

Multi-Tenant Investment Opportunity

1649 East Main St, Easley, SC 29640

6,250 SF multi-tenant investment opportunity in Easley, SC.

  • 6,250 SF multi tenant investment opportunity
  • Located on Calhoun Memorial Highway
  • Easley, SC address
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Easley Showroom/Office/Warehouse For Sale
$1,400,000
18,000 SF

Easley Showroom/Office/Warehouse For Sale

18,000 SF showroom/office/warehouse in Easley, SC. Owner/user opportunity.

1017 Powdersville Rd, Easley, SC 29642
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Easley Office Building For Sale
Contact for pricing
7,163 SF

Easley Office Building For Sale

Office building on a 0.29-acre lot, suitable for owner-occupant.

401 E 1St Ave, Easley, SC 29640
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Industrial Building with Long-Term Tenant
Contact for pricing
182,508 SF

Industrial Building with Long-Term Tenant

182,508 SF light manufacturing building with long-term tenant.

1208 Old Norris Rd, Liberty, SC 29657
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Pickens Office Building - Great Potential
$300,000
0.76 Acres

Pickens Office Building - Great Potential

Spacious office building, ample parking, city limits.

837 Pendleton Street Ext, Pickens, SC 29671
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Clemson Medical Office Building
$575,000
0.37 Acres

Clemson Medical Office Building

Prime medical office, 8,000 SF, 0.37 acres

0 Chapman Hill Rd, Central, SC 29631
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Based on your search, we've compiled 379 Potential Opportunities for your consideration. Besides 7 Active listings in Pickens County, SC, we suggest exploring several alternatives: similar 371 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Easley Commercial Land For Sale
$55,000
0.39 Acres

Easley Commercial Land For Sale

0.39 acre commercial lot with road frontage in Easley, SC.

315 Gentry Memorial Hwy, Easley, SC 29640
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Explore Off-Market Properties in Pickens County, SC

Consider similar Off-Market properties in Pickens County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

522 College Ave

522 College Ave

MEDICAL BUILDING • 4,750 SF
Value Estimation
$545,000
522 College Ave, Clemson, SC 29631-1443
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100 Country Walk Ln

100 Country Walk Ln

OFFICE BUILDING • 1,726 SF
Value Estimation by Request
100 Country Walk Ln, Clemson, SC 29631
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402 Pendleton Rd

402 Pendleton Rd

OFFICE BUILDING • 1,536 SF
Value Estimation by Request
402 Pendleton Rd, Clemson, SC 29631-2242
View details
122 Strode Cir

122 Strode Cir

OFFICE BUILDING • 1,519 SF
Value Estimation by Request
122 Strode Cir, Clemson, SC 29631-1484
View details
236 Main St

236 Main St

OFFICE BUILDING • 417 SF
Value Estimation by Request
236 Main St, Central, SC 29630-4159
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6728 Calhoun Memorial Hwy

6728 Calhoun Memorial Hwy

OFFICE BUILDING • 912 SF
Value Estimation by Request
6728 Calhoun Memorial Hwy, Easley, SC 29640-3672
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Sunset, SC 29685

Sunset, SC 29685

OFFICE BUILDING • 342 SF
Value Estimation by Request
Sunset, SC 29685
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110 Settlement Blvd

110 Settlement Blvd

OFFICE BUILDING • 231 SF
Value Estimation by Request
110 Settlement Blvd, Sunset, SC 29685
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306 Cedar Rock St, Unit 1

306 Cedar Rock St, Unit 1

OFFICE BUILDING • 9,472 SF
Value Estimation
$680,000
306 Cedar Rock St, Pickens, SC 29671-2412
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1017 Tiger Blvd

1017 Tiger Blvd

OFFICE BUILDING • 5,087 SF
Value Estimation by Request
1017 Tiger Blvd, Clemson, SC 29631-1416
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Easley, SC 29640

Easley, SC 29640

OFFICE BUILDING • 2,128 SF
Value Estimation by Request
Easley, SC 29640
View details
1098 Pendleton St

1098 Pendleton St

OFFICE BUILDING • 864 SF
Value Estimation by Request
1098 Pendleton St, Easley, SC 29642-1042
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865 Pendleton St

865 Pendleton St

MEDICAL BUILDING • 1,716 SF
Value Estimation by Request
865 Pendleton St, Pickens, SC 29671-2578
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1270 Walhalla Hwy

1270 Walhalla Hwy

OFFICE BUILDING • 9.00 Acres
Value Estimation by Request
1270 Walhalla Hwy, Pickens, SC 29671
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539 Pendleton St

539 Pendleton St

OFFICE BUILDING • 1,680 SF
Value Estimation by Request
539 Pendleton St, Easley, SC 29640-3574
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111 Roper Rd

111 Roper Rd

MEDICAL BUILDING • 4,829 SF
Value Estimation
$665,000
111 Roper Rd, Easley, SC 29640-8805
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4821 Calhoun Memorial Hwy

4821 Calhoun Memorial Hwy

OFFICE BUILDING • 3,668 SF
Value Estimation by Request
4821 Calhoun Memorial Hwy, Easley, SC 29640-3853
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Pickens County, SC Office Properties & Spaces Investment Opportunities Market Analysis

Explore 378 office properties & spaces for sale in Pickens County, SC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 15,611,383 square feet of properties for sale, with an estimated market value of $77,620,000.

Sale prices for office spaces in Pickens County, SC start at $55,000, averaging $554,428, and reaching up to $5,030,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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