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Greenville County, SC Office Properties & Spaces for Sale

67 results
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Charming Updated Office in Simpsonville
Contact for pricing
0.37 Acres

Charming Updated Office in Simpsonville

312 S Main St, Simpsonville, SC 29681

Prime location in Historic Downtown Simpsonville with rustic charm.

  • Prime location in Historic Downtown Simpsonville with excellent visibility.
  • Five potential offices, including one convertible to a conference room.
  • Elegantly finished reception area.
  • Full kitchen and full bathroom.
  • Ample parking with approximately 12–14 spaces.
Updated: Feb 5
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Powdersville Office Building with Retail Potential
$449,000
0.31 Acres

Powdersville Office Building with Retail Potential

3127 Highway 153, Piedmont, SC 29673

2,016 SF office building with retail potential in Powdersville.

  • High‑exposure location with over 200 feet of frontage on Highway 153.
  • Retail potential in addition to office use.
  • Fully handicap accessible with dedicated handicap parking spaces.
  • Median break on Highway 153 allows easy access from both directions.
  • Includes 6 office spaces, 2 restrooms, kitchen, meeting room, and storage.
Updated: Jan 18
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Greenville Office For Sale
$895,000
0.25 Acres

Greenville Office For Sale

Office property available for purchase in Greenville, South Carolina.

204 Mills Ave, Greenville, SC 29605
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Office Space in Simpsonville, SC
Contact for pricing
0.18 Acres

Office Space in Simpsonville, SC

Office property for sale in Simpsonville, South Carolina.

131 SE Main St, Simpsonville, SC 29681
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New Commercial Unit For Lease
Contact for pricing
2,500 SF

New Commercial Unit For Lease

New commercial unit for lease with versatile space and prime location.

1 Brookside Unit 2 Dr, Travelers Rest, SC 29690
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Greenville Office Near Medical Facilities
$950,000
0.35 Acres

Greenville Office Near Medical Facilities

Premium office space with subdivision potential near Prisma Health.

101 Chapman St, Greenville, SC 29605
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Office Space with Included Utilities
Contact for pricing
1.63 Acres

Office Space with Included Utilities

Office space for sale with utilities and shared amenities.

552 Memorial Drive Ext, Greer, SC 29651
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Mixed-Use Commercial Property on Highway
$687,000
1.07 Acres

Mixed-Use Commercial Property on Highway

Mixed-use commercial property on 1.07 acres with highway frontage.

2821 Poinsett Hwy, Greenville, SC 29609
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Professional Office Suite on Pelham
Contact for pricing
0.44 Acres

Professional Office Suite on Pelham

First floor office suite available for sublease through February 2029.

330B Pelham Rd, Greenville, SC 29615
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New Commercial Unit For Lease
Contact for pricing
2,500 SF

New Commercial Unit For Lease

Brand new commercial unit available for lease in Travelers Rest.

1 Brookside Dr, Travelers Rest, SC 20690
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Office Space in Greenville, SC
$350,000
0.03 Acres

Office Space in Greenville, SC

Office space for sale in Greenville, South Carolina.

232 Adley Way, Greenville, SC 29607
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New Commercial Unit For Lease
Contact for pricing
5,000 SF

New Commercial Unit For Lease

Brand new commercial unit available for lease in Travelers Rest.

1 Brookside Unit 3 Dr, Travelers Rest, SC 29690
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Greenville Commercial Parcel For Sale
$199,999
0.45 Acres

Greenville Commercial Parcel For Sale

High-visibility corner lot ideal for retail, office, or service business.

1519 Cedar Lane Rd, Greenville, SC 29611
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Retail/Office Space on E. North
$325,000
1,750 SF

Retail/Office Space on E. North

Retail, office, or service space for sale near Downtown Greenville.

2704 E North St, Greenville, SC 29615
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Greenville Office with Private Restroom
$499,000
2,384 SF

Greenville Office with Private Restroom

Office space near downtown Greenville with private offices and parking.

106 S Texas Ave, Greenville, SC 29611
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Freestanding Office/Medical Building For Sale
$430,000
2,306 SF

Freestanding Office/Medical Building For Sale

Two-story, 2,306 SF office/medical building in established office park.

4501 Old Spartanburg Rd, Taylors, SC 29687
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Mauldin Commercial Site For Sale
$200,000
1.00 Acre

Mauldin Commercial Site For Sale

1+ acre lot approved for medical offices in growing area.

Corn And Miller Rd, Mauldin, SC 29607
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Downtown Greenville Office Space Available
Contact for pricing
1.00 Acre

Downtown Greenville Office Space Available

Office suites available in downtown Greenville, utilities included.

1010 E North St, Greenville, SC 29601
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Versatile Warehouse/Flex Property For Sale
$3,400,000
25,790 SF

Versatile Warehouse/Flex Property For Sale

Warehouse/flex property with redevelopment potential in a high-traffic commercial area.

825 Old Airport Rd, Greenville, SC 29607
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Office Space with Mezzanine
$1,500,000
2,500 SF

Office Space with Mezzanine

Office space featuring private offices, mezzanine, and outdoor patio.

103 Wade Hampton Blvd, Greenville, SC 29609
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Sublease Office Space Available
$295,000
2,200 SF

Sublease Office Space Available

Office space for sublease near Downtown, expires January 2026.

157-159 Commons Way, Greenville, SC 29611
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Office Building with Billboard Income
$398,500
0.47 Acres

Office Building with Billboard Income

Office property in Greenville, SC with additional billboard income.

1908 N Pleasantburg Dr, Greenville, SC 29609
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Mauldin Office Building For Sale
$299,000
1,800 SF

Mauldin Office Building For Sale

Office building with private offices, conference room, and break area.

108 Renaissance Cir, Mauldin, SC 29662
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Greer SC Industrial/Flex Space
Contact for pricing
10,000 SF

Greer SC Industrial/Flex Space

10,000 SF industrial/flex space near GSP Airport.

175 Brookshire Rd, Greer, SC 29651
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Greenville County, SC Office Properties & Spaces Investment Opportunities Market Analysis

Explore 2519 office properties & spaces for sale in Greenville County, SC, showcased through 67 active listings on our real estate platform. These investment opportunities span a total of 80,395,377 square feet of properties for sale, with an estimated market value of $1,125,115,649.

Sale prices for office spaces in Greenville County, SC start at $60,000, averaging $851,715, and reaching up to $23,660,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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