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    Lancaster County, PA Office Properties & Spaces for Sale

    38 results
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    Move-in Ready Office Building Downtown
    $300,000
    0.10 Acres

    Move-in Ready Office Building Downtown

    112 W Main St, Ephrata, PA 17522

    Office building in downtown Ephrata, PA, with high visibility.

    • Move‑in ready office building in the heart of downtown Ephrata.
    • High visibility location on US 322 with 14,000‑16,000 vehicles passing daily.
    • Functional layout with reception area, multiple private offices, kitchenette, and bathrooms on both floors.
    • Ample storage space with attic access and a full basement.
    • Convenient parking with on‑street options and quick access to a public parking lot, plus a detached two‑car garage.
    Updated: Feb 4
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    Historic Mixed-Use Commercial Building
    $649,900
    0.06 Acres

    Historic Mixed-Use Commercial Building

    22 S 2Nd St, Columbia, PA 17512

    Unique property blending historic charm with modern convenience.

    • Prime downtown location suitable for commercial and/or residential use
    • Versatile property currently operating as a retail store, event space, and coffee shop with a second‑floor living space
    • Historic building (built in 1900) with unique architectural details, including cantilevered display windows and distinctive brickwork
    • Updated features include refinished wood floors and custom hand‑blown glass light fixtures
    • Full bathroom on every floor and a full kitchen on the second floor
    Updated: Feb 6
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    Lancaster Office Space For Sale
    $169,900
    1,000 SF

    Lancaster Office Space For Sale

    Second-floor office space with private offices and conference room.

    2938-1 Columbia Ave, Lancaster, PA 17603
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    Lancaster Office Investment Opportunity
    $6,000,000
    39,610 SF

    Lancaster Office Investment Opportunity

    Stabilized office property leased until 2030 in Lancaster, PA.

    3020 Columbia Ave, Lancaster, PA 17603
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    Historic Townhouse with Commercial Space
    $1,895,000
    5,500 SF

    Historic Townhouse with Commercial Space

    Historic Lancaster townhouse with commercial space and residential living.

    121-123 E King St, Lancaster, PA 17602
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    Commercial Space on Busy Route 743
    $549,900
    0.48 Acres

    Commercial Space on Busy Route 743

    Commercial space suitable for medical offices, retail, or storage.

    915 N Hanover St, Elizabethtown, PA 17022
    View details
    Lititz Office/Retail Building For Sale
    $2,400,000
    9,200 SF

    Lititz Office/Retail Building For Sale

    9,200 SF office building on 0.96 acres in Lititz, PA.

    743 S Broad St, Lititz, PA 17543
    View details
    Medical Office Building in Lititz
    $2,100,000
    1.50 Acres

    Medical Office Building in Lititz

    7,501 SF medical office building for sale or lease.

    640 E Oregon Rd, Lititz, PA 17543
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    Adaptive Re-Use Project Opportunity
    $699,000
    7,702 SF

    Adaptive Re-Use Project Opportunity

    Two buildings with courtyard, ideal for creative revitalization project.

    20 N 2Nd St, Columbia, PA 17512
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    Main Street Commercial Building For Sale
    Contact for pricing
    3,009 SF

    Main Street Commercial Building For Sale

    Commercial building in Terre Hill, PA with retail and office potential.

    100 W Main St, Terre Hill, PA 17581
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    Professional Condo in Downtown Lancaster
    $115,000
    1,242 SF

    Professional Condo in Downtown Lancaster

    Upscale condo with offices and conference room in downtown Lancaster.

    128 East Grant St, Lancaster, PA 17602
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    Medical Building Near Residential Community
    $1,950,000
    15,710 SF

    Medical Building Near Residential Community

    Three-story medical building with grade-level entrances and elevator access.

    3045 Marietta Ave, Lancaster, PA 17601
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    Ephrata Commercial Building on Route
    Contact for pricing
    9,640 SF

    Ephrata Commercial Building on Route

    Commercial building in highly visible location, value-add opportunity.

    560 S Reading Rd, Ephrata, PA 17522
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    Leola Office Building For Sale
    Contact for pricing
    8,832 SF

    Leola Office Building For Sale

    8,832 SF office building with tenant and vacant suite.

    20 Trinity Dr, Leola, PA 17540
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    Versatile Commercial Space on Rt. 743
    $549,900

    Versatile Commercial Space on Rt. 743

    Adaptable commercial building with production, office, and storage areas.

    915 N Hanover St, Elizabethtown, PA 17022
    View details
    Freestanding Building with Parking Area
    Contact for pricing
    1,128 SF

    Freestanding Building with Parking Area

    High-traffic location, leased through 2027, future owner/user opportunity.

    454 N Prince St, Lancaster, PA 17603
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    Downtown Lancaster Office Building
    Contact for pricing
    30,008 SF

    Downtown Lancaster Office Building

    30,000 SF office building in downtown Lancaster for sale.

    39 N Duke St, Lancaster, PA 17602
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    Downtown Lancaster Assemblage For Sale
    $2,295,000
    30,008 SF

    Downtown Lancaster Assemblage For Sale

    Three-parcel assemblage in downtown Lancaster with single tenant net lease.

    37-45 North Duke St, Lancaster, PA 17603
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    Downtown Lancaster Landmark Building
    Contact for pricing

    Downtown Lancaster Landmark Building

    Iconic 3-story building with retail potential in downtown Lancaster.

    100 N Queen St, Lancaster, PA 17603
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    Lancaster Office Suite - Prime Location
    Contact for pricing

    Lancaster Office Suite - Prime Location

    First-floor corner office, six private offices.

    120 Pointe Blvd, Lancaster, PA 17601
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    Ephrata Office Space - Main Street
    Contact for pricing

    Ephrata Office Space - Main Street

    Two-room office, all utilities included.

    607 Main St, Ephrata, PA 17522
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    Lititz Office Space: Prime Location
    Contact for pricing
    26.30 Acres

    Lititz Office Space: Prime Location

    Class A Office, Stunning Amenities, Lease Available

    100 Millport Rd, Lititz, PA 17543
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    Lititz Office Building: Prime Location
    Contact for pricing
    2.50 Acres

    Lititz Office Building: Prime Location

    Standalone Office, Abundant Parking, Flexible Lease

    118 Airport Rd, Lititz, PA 17543
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    Lancaster City Center Office Building
    $10,995,000
    77,294 SF

    Lancaster City Center Office Building

    Prime Lancaster location, 77,294 SF, multi-tenant

    100 Queen St, Lancaster, PA 17603
    View details

    Lancaster County, PA Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 2440 office properties & spaces for sale in Lancaster County, PA, showcased through 38 active listings on our real estate platform. These investment opportunities span a total of 145,445,964 square feet of properties for sale, with an estimated market value of $1,263,464,800.

    Sale prices for office spaces in Lancaster County, PA start at $80,000, averaging $853,692, and reaching up to $13,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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