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    Syracuse, NY Office Spaces for Sale

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    Nedrow, NY Sentinel Heights, NY Liverpool, NY
    21 results
    North Syracuse Medical Office Building
    $400,000
    2,244 SF
    North Syracuse Medical Office Building

    105 N Main Street, Syracuse, NY 13212

    Well-maintained medical office in a high-growth area.
    • New roof installed in 2024 significantly reduces capital expenditure risk.
    • High‑visibility location on North Main Street with 15 dedicated parking spaces.
    • Professionally designed 2,244 SF medical office layout with reception, retail, exam rooms, offices, and lab.
    • Zoned for medical and professional office use, suitable for various practices.
    • Located in the rapidly growing Central New York economic corridor, near the Micron Technology facility.
    Updated: May 19
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    Versatile Commercial/Industrial Building, Syracuse
    $379,000
    4,408 SF
    Versatile Commercial/Industrial Building, Syracuse

    6730 Townline Road, Syracuse, NY 13211

    4,408 sq ft commercial/industrial building in a busy area.
    • 4,408 sq ft commercial/industrial building in a busy commercial‑industrial area
    • Flexible layout with 6 front offices, cafeteria/break room, and large rear meeting/conference area with 2 additional bathrooms
    • 25' x 38' shop area with large compressor and air lines
    • Front and rear parking for approx. 12 vehicles with potential for additional parking
    • Multi‑zone heating and air conditioning
    Updated: Nov 21, 2025
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    610 Oak St, Syracuse
    $425,000
    6,755 SF
    610 Oak St, Syracuse

    Historic Firehouse Converted to Office Space

    610 Oak St, Syracuse, NY 13203

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    Syracuse Commercial Building For Sale
    $250,000
    1,920 SF
    Syracuse Commercial Building For Sale

    Commercial building with heated warehouse space and office, Syracuse, NY.

    401 Wolf St, Syracuse, NY 13208

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    Converted Firehouse in Syracuse, NY
    $425,000
    7,000 SF
    Converted Firehouse in Syracuse, NY

    Retail space near downtown.

    610 Oak St, Syracuse, NY 13203

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    Syracuse Flex Space Opportunity
    $89,000
    1,912 SF
    Syracuse Flex Space Opportunity

    1912 SF flex space near Syracuse and major routes.

    1455 Burnet Ave, Syracuse, NY 13206

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    Versatile Flex Building with Storage
    $899,000
    15,800 SF
    Versatile Flex Building with Storage

    15,800± SF flex building with industrial outside storage.

    559 State Fair Blvd, Syracuse, NY 13204

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    Fully Leased Syracuse Industrial Facility
    $1,200,000
    12,000 SF
    Fully Leased Syracuse Industrial Facility

    12,000 SF industrial facility in Syracuse's industrial corridor.

    532 State Fair Blvd, Syracuse, NY 13204

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    Multi-Tenant Office Building For Sale
    $990,000
    20,808 SF
    Multi-Tenant Office Building For Sale

    Multi-tenant office building with potential sale/leaseback opportunity.

    990 James St, Syracuse, NY 13203

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    Fully Leased Syracuse Industrial Portfolio
    $2,900,000
    42,776 SF
    Fully Leased Syracuse Industrial Portfolio

    Two-building industrial investment totaling 42,776 SF on 2.64 acres.

    113 Falso Dr, Syracuse, NY 13211

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    S Salina St Office Building
    $249,900
    2,562 SF
    S Salina St Office Building

    Office building on a major commercial thoroughfare, great investment.

    4709 S Salina St, Syracuse, NY

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    Downtown Syracuse Office Building
    $3,567,324
    26,000 SF
    Downtown Syracuse Office Building

    26,000 SF office building for sale in Syracuse.

    359 S Salina St, Syracuse, NY

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    Erie Boulevard Office Space For Sale
    $1,500,000
    6,000 SF
    Erie Boulevard Office Space For Sale

    Office space for sale on a high-traffic retail corridor.

    3125 Erie Blvd E, Syracuse, NY

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    Syracuse Office Building For Sale
    $1,950,000
    15,299 SF
    Syracuse Office Building For Sale

    Office building in Syracuse, NY, with ample parking.

    105 Twin Oaks Dr, Syracuse, NY

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    Mixed-Use Building with Dental Practice
    $185,000
    2,600 SF
    Mixed-Use Building with Dental Practice

    2600 SF building with dental practice and apartment.

    1500 Grant Blvd and Mayar St, Syracuse, NY

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    Development Land on East Taft
    $1,000,000
    61.40 Acres
    Development Land on East Taft

    Over 25 acres of development land with full utilities.

    6966 E Taft Road, Dewitt, NY 13057

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    North Syracuse Office/Medical Building
    Contact for pricing
    North Syracuse Office/Medical Building

    Two-story office building in North Syracuse, available for sale.

    5232 Witz Dr, Syracuse, NY 13212

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    Mixed-Use Warehouse/Office/Retail Space
    $2,900,000
    42,416 SF
    Mixed-Use Warehouse/Office/Retail Space

    Versatile warehouse, office, and retail space near Route 690.

    1641 E Genesee St, Syracuse, NY

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    James Street Office Building For Sale
    $695,000
    17,888 SF
    James Street Office Building For Sale

    High-visibility Syracuse office building with ample parking and renovated restrooms.

    750 James St, Syracuse, NY

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    Well-Maintained Two-Story Office Building
    $1,695,000
    22,867 SF
    Well-Maintained Two-Story Office Building

    Two-story office building with basement and excellent onsite parking.

    5232 Witz Dr, N Syracuse, NY

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    Syracuse Office Property for Sale
    $599,900
    13,000 SF
    Syracuse Office Property for Sale

    Office property available in Syracuse, New York, totaling 13,000 square feet.

    901 Lodi St & Willow St E, Syracuse, NY 13203

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    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 21 Active Listings in Syracuse, NY, we suggest to view alternatives - similar 51 Off-Market properties to explore as potential leads.

    Off-Market Properties in Syracuse, NY

    Consider similar Off-Market properties in Syracuse, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    613 Erie W Blvd, Unit 17
    OFFICE BUILDING
    67,393 SF Lot: 2.20 Acres
    Estimated value
    $5,310,000
    Unit 17

    613 Erie W Blvd, Syracuse, NY 13204-2424

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    5232 Witz Dr
    OFFICE BUILDING
    18,912 SF Lot: 2.08 Acres

    5232 Witz Dr, Syracuse, NY 13212-6501

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    1004 James St Oak St
    RADIO OR TV STATION
    22,540 SF Lot: 0.86 Acres
    Estimated value
    $870,000

    1004 James St Oak St, Syracuse, NY 13203

    View details

    Syracuse, NY Office Spaces Investment Opportunities Market Analysis

    Explore 72 office spaces for sale in Syracuse, NY, showcased through 21 active listings on our real estate platform. These investment opportunities span a total of 264,255 square feet of properties for sale, with an estimated market value of $21,299,124.

    Sale prices for office spaces in Syracuse, NY start at $89,000, averaging $1,121,006, and reaching up to $3,567,324 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 68
    Office buildings 20
    Medical Office Space 12
    Creative space 4

    Property Size Breakdown

    The majority of commercial real estate listings in Syracuse fall within the 100,000+ square foot range.

    Demographics Overview

    Population 229K
    Population Growth (5Y) -0.9%
    Median Household Income $59,936
    College Educated 33.4%

    High-Yield Neighborhoods for Investment

    Identify Syracuse submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    13206 $89K
    13208 $250K
    13212 $400K
    13203 $610K
    13204 $1M

    Taxes & Financing

    Average Loan-to-Value 65.0%

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    Most Searched ZIP Codes in Syracuse, NY

    • 13203
    • 13204
    • 13211
    • 13212
    • 13057
    • 13206
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