Health Care

Syracuse, NY Healthcare Properties for Sale

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Jamesville, NY Camillus, NY Nedrow, NY Salina, NY East Syracuse, NY Fayetteville, NY Clay, NY Lafayette, NY
Single-Story Medical Office
Updated: May 19
Single-Story Medical Office

105 N Main Street, Syracuse, NY 13212

$400,000
2,244 sqft 0.23 AC lot
2,244 SF single‑level medical office building
0.2317‑acre site with 15 dedicated parking spaces
Interior includes exam rooms, private offices, optical retail, and laboratory space
New asphalt roof installed in 2024
Built in 1950 with a modern interior buildout
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Mixed-Use Property with Apartment
Updated: Apr 16, 2025
Mixed-Use Property with Apartment

1500 Grant Blvd, Syracuse, NY 13208

Contact for pricing
2,600 sqft
Approx. 2600 SF mixed‑use building zoned COM 1
Five treatment rooms with five chairs
One panoramic X‑ray machine and four intraoral X‑ray machines
Two‑bedroom apartment on the 2nd floor
Unfinished 3rd floor attic
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Syracuse Medical Center Opportunity
Syracuse Medical Center Opportunity

3229 E Genesee St, Syracuse, NY 13214

Contact for pricing
23,500 sqft

23,500 SF clinical center available in Syracuse, NY.

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See hot listings in Syracuse

Scored against comparables nationwide. These are worth a look.

Scored against comparables nationwide. These are worth a look.

Cap Rate available after sign in
Est. NOI available after sign in
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Based on your search, we've compiled 59 Potential Opportunities for your consideration. Besides 3 Active listings in Syracuse, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 52 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Medical Office with Exam Rooms
Medical Office with Exam Rooms

399 Grant Avenue Road, Auburn, NY 13021

$1,300,000
4,536 sqft 0.71 AC lot

Purpose-built medical office layout with professional rooms, reception, laboratory space, storage, and dedicated parking.

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Corner Storefront Property
Corner Storefront Property

30 Mary Street, Auburn, NY 13021

$134,900
2,160 sqft 0.05 AC lot

Existing salon setup includes private rooms, a kitchenette, laundry, and central air in a flexible corner property.

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Level 3 Congregate Care Facility
Level 3 Congregate Care Facility

4 Washington Park, Oxford, NY 13830

$325,000
10,545 sqft 0.56 AC lot

Regulated senior housing property with a commercial kitchen, resident common areas, and accessible ramp approach.

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Level 3 Congregate Care Facility
Level 3 Congregate Care Facility

4 Washington Park, Oxford, NY 13830

$325,000
10,545 sqft

Regulated adult care property with resident accommodations, shared spaces, commercial kitchen, and updated mechanical systems.

View details

Off-Market Properties in Syracuse, NY

Consider similar Off-Market properties in Syracuse, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

906 James St
HOMES (RETIRED, NURSING)

906 James St, Syracuse, NY 13203-2503

Estimated value: by Request
76,800 sqft 1.70 AC lot
View details
5008 Brittany Ln
MEDICAL CLINIC

5008 Brittany Ln, Syracuse, NY 13215

Estimated value:
$1,945,000
70,668 sqft 5.35 AC lot
View details
1316 Fayette St
HOMES (RETIRED, NURSING)

1316 Fayette St, Syracuse, NY 13210-1109

Estimated value:
$340,000
6,677 sqft 0.78 AC lot
View details
7430 Buckley Rd
HOMES (RETIRED, NURSING)

7430 Buckley Rd, North Syracuse, NY 13212-1947

Estimated value:
$525,000
33,735 sqft 3.38 AC lot
View details
504 Delaware St Sabine St
MEDICAL CLINIC

504 Delaware St Sabine St, Syracuse, NY 13204

Estimated value:
$270,000
11,016 sqft 0.36 AC lot
View details
190 Intrepid Ln
MEDICAL CLINIC

190 Intrepid Ln, Syracuse, NY 13205-2545

Estimated value:
$4,055,000
16,624 sqft 1.40 AC lot
View details
918 James St
HOMES (RETIRED, NURSING)

918 James St, Syracuse, NY 13203-2503

Estimated value:
$1,065,000
76,800 sqft 1.30 AC lot
View details
703 Onondaga St
HOMES (RETIRED, NURSING)

703 Onondaga St, Syracuse, NY 13204-4026

Estimated value:
$335,000
7,640 sqft 1.00 AC lot
View details
161 Intrepid Ln
MEDICAL CLINIC

161 Intrepid Ln, Syracuse, NY 13205-2548

Estimated value:
$305,000
6,000 sqft 0.66 AC lot
View details
6227 Thompson Rd
MEDICAL CLINIC

6227 Thompson Rd, Syracuse, NY 13206-1405

Estimated value:
$335,000
3,600 sqft 1.01 AC lot
View details
813 Fay Rd
MEDICAL CLINIC

813 Fay Rd, Syracuse, NY 13219-3009

Estimated value:
$1,605,000
58,012 sqft 21.64 AC lot
View details
973 James St To Highland Ave
MEDICAL CLINIC

973 James St To Highland Ave, Syracuse, NY 13203

Estimated value:
$1,185,000
53,509 sqft 2.39 AC lot
View details
5075 Seneca Tpke
HOMES (RETIRED, NURSING)

5075 Seneca Tpke, Syracuse, NY 13215-3216

Estimated value:
$2,060,000
303,913 sqft 74.20 AC lot
View details
6900 Buckley Rd
HOMES (RETIRED, NURSING)

6900 Buckley Rd, N Syracuse, NY 13212-4042

Estimated value:
$1,430,000
109,642 sqft 22.17 AC lot
View details
2112 Erie E Blvd
MEDICAL CLINIC

2112 Erie E Blvd, Syracuse, NY 13224-1041

Estimated value:
$435,000
15,511 sqft 1.14 AC lot
View details
5823 Widewaters Pkwy
MEDICAL CLINIC

5823 Widewaters Pkwy, Syracuse, NY 13214

Estimated value:
$1,140,000
64,476 sqft 7.00 AC lot
View details
626-72 Salina S To Clinton St
MEDICAL CLINIC

626-72 Salina S To Clinton St, Syracuse, NY 13202

Estimated value:
$1,185,000
79,763 sqft 2.59 AC lot
View details
228 Lafayette Rd
MEDICAL CLINIC

228 Lafayette Rd, Syracuse, NY 13205-2921

Estimated value:
$405,000
11,388 sqft 2.59 AC lot
View details
116 Martin Luther King E
HOMES (RETIRED, NURSING)

116 Martin Luther King E, Syracuse, NY 13205-1110

Estimated value:
$1,170,000
80,870 sqft 3.37 AC lot
View details
4330 Onondaga Blvd
HOMES (RETIRED, NURSING)

4330 Onondaga Blvd, Syracuse, NY 13219-3030

Estimated value:
$825,000
55,593 sqft 6.52 AC lot
View details
5792 Widewaters Pkwy
MEDICAL CLINIC

5792 Widewaters Pkwy, Syracuse, NY 13214-1847

Estimated value:
$420,000
15,128 sqft 5.13 AC lot
View details

Syracuse, NY Healthcare Properties Market Trends and Statistics

Explore 55 healthcare properties for sale in Syracuse, NY, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 28,344 square feet of properties for sale, with an estimated market value of $400,000.

Sale prices for medical real estate in Syracuse, NY average $400,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Medical centers 3
Rehabilitation centers 1
Senior Housing / Retirement Homes 1

Demographics Overview

Population 229K
Population Growth (5Y) -0.9%
Median Household Income $59,936
College Educated 33.4%

High-Yield Neighborhoods for Investment

Identify Syracuse submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
13212 $400K

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Onondaga County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in Syracuse fall within the 100,000+ square foot range.

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