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    Syracuse, NY Mixed-use Properties for Sale

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    Two-Story Mixed-Use Property
    Updated: May 1
    Two-Story Mixed-Use Property

    207 Chapel Drive, Syracuse, NY 13219

    $1,400,000
    8,205 sqft 0.58 AC lot
    8,205‑square‑foot, two‑story building on a 0.5825‑acre lot
    Main level includes private offices, conference room, kitchenette, and oversized commercial bathrooms
    Second floor contains six bedrooms and bathrooms
    Eight‑car parking area, oversized two‑car garage, and large dry basement
    Built in 2009 with central air and zoned forced‑air natural gas heat
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    Mixed-Use Building with Apartment
    Updated: Aug 10
    Mixed-Use Building with Apartment

    200 W Seneca St & Marcellus Street, Syracuse, NY 13204

    $249,900
    4,208 sqft 0.08 AC lot
    4,208‑square‑foot mixed‑use building on a 0.08‑acre parcel
    Second‑floor apartment included with commercial space
    Frame construction with wood siding
    Forced‑air natural gas heating
    Public water and public sewer
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    Five-Story Mixed-Use Redevelopment
    Five-Story Mixed-Use Redevelopment

    313 S salina st, Syracuse, NY 13202

    $1,200,000

    Historic building with a cleared interior, new roof, and plans for apartments over ground-floor retail.

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    See what stands out in Onondaga County

    We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

    We check every listing here. A few are worth a second look.

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    Established Restaurant with Apartments
    Established Restaurant with Apartments

    313 North Geddes Street, Syracuse, NY 13204

    $2,750,000
    13,737 sqft 1.20 AC lot

    Fully equipped operation with staff in place, two kitchens, a full bar, and seasonal patio.

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    Mixed-Use Development Land Site
    Mixed-Use Development Land Site

    1951 Fayette St E & Ives St, Syracuse, NY 13210

    $50,000
    1.42 AC lot

    Five parcels totaling 1.42 acres are offered for proposed commercial, residential, or mixed-use development planning.

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    Mixed-Use Property with Apartments
    Mixed-Use Property with Apartments

    911 PARK AVE, Syracuse, NY 13204

    $385,000
    8,880 sqft

    Fully leased building combining warehouse-flex space, retail display areas, offices, and renovated residential units.

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    Mixed-Use Retail and Apartments
    Mixed-Use Retail and Apartments

    400 Butternut Street, Syracuse, NY 13208

    $5,500,000
    32,598 sqft

    Fully occupied mixed-use building with first-floor retail anchored by Kinney Drugs and Subway plus three floors of 2-bedroom apartments.

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    High-Rise Apartment Building
    High-Rise Apartment Building

    770 James Street, Syracuse, NY 13203

    $22,657,450
    245,765 sqft

    Self-contained residential community with integrated commercial space and on-site professional and restaurant services.

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    Mixed-Use Property with Warehouse
    Mixed-Use Property with Warehouse

    1004 BUTTERNUT ST, Syracuse, NY 13208

    $235,000
    7,181 sqft

    Two-family residence includes flexible commercial space, a separate warehouse, and substantial paved parking areas.

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    Mixed-Use Redevelopment Property
    Mixed-Use Redevelopment Property

    2616 Brewerton Road, Mattydale, NY 13211

    Contact for pricing
    10,908 sqft

    Centrally located near the I-81 and I-90 interchange with redevelopment potential into multi-tenant or standalone buildings.

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    Mixed-Use Commercial Property
    Mixed-Use Commercial Property

    314 LAKESIDE RD, Syracuse, NY 13209

    Contact for pricing
    13,221 sqft

    Commercial, office, and manufacturing zoning supports a range of mixed-use applications.

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    Historic Mixed-Use Building
    Historic Mixed-Use Building

    108 West Jefferson Street, Syracuse, NY 13202

    Contact for pricing
    2,726 sqft

    1928 property combines an office tower, cinema theater, and wraparound retail frontage.

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    Apartment Building With Street-Level Retail
    Apartment Building With Street-Level Retail

    900 East Fayette Street, Syracuse, NY 13210

    Contact for pricing
    53,688 sqft

    Student housing property combines apartment layouts with ground-floor commercial space near Syracuse University.

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    Mixed-Use Property with High Income
    Mixed-Use Property with High Income

    1639 N Salina St, Syracuse, NY 13202

    $615,000
    6,024 sqft

    Corner lot with commercial space and four apartments, fully rented.

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    Ten-Unit Mixed-Use Investment Property
    Ten-Unit Mixed-Use Investment Property

    3100-006 James St, Syracuse, NY 13206

    $799,000
    0.14 AC lot

    Income-producing property with apartments and commercial storefronts.

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    Mixed-Use Property
    Mixed-Use Property

    323 S Salina Street, Syracuse, NY 13202

    Contact for pricing
    15,250 sqft

    Commercial property combining multiple potential use categories within one building.

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    Four-Unit Mixed-Use Property
    Four-Unit Mixed-Use Property

    1205 South Geddes Street, Syracuse, NY 13204

    $249,000

    Includes a storefront and three residential apartments within one income-producing building.

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    Mixed-Use Property with Apartment
    Mixed-Use Property with Apartment

    1500 Grant Blvd, Syracuse, NY 13208

    Contact for pricing
    2,600 sqft

    Includes treatment rooms, imaging equipment, and a two-bedroom second-floor apartment.

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    Mixed-Use Development Site
    Mixed-Use Development Site

    2704 Lodi St, Syracuse, NY 13208

    Contact for pricing
    0.56 AC lot

    Mixed-use acreage with on-site parking and access to major regional routes.

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    Mixed-Use Building with Commercial Space
    Mixed-Use Building with Commercial Space

    926 Burnet Ave, Syracuse, NY 13203

    Contact for pricing
    6,603 sqft

    Six-unit property combines apartment occupancy with a ground-floor commercial area and separately metered utilities.

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    Mixed-Use 4-Unit Property
    Mixed-Use 4-Unit Property

    1417 Milton Ave, Geddes, NY 13209

    $260,000

    Four-unit building with two commercial spaces and two residential apartments for sale at 1417 Milton Ave.

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    Development Opportunity Near Syracuse University
    Development Opportunity Near Syracuse University

    1641 E Genesee St, Syracuse, NY 13210

    Contact for pricing
    51,751 sqft

    Three-story building with development potential near Syracuse University.

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    Mixed-Use Building with Separate Entrances
    Mixed-Use Building with Separate Entrances

    387-89 Midler Avenue North & City Line, Syracuse, NY 13206

    Contact for pricing

    Two-level property includes a bar/restaurant or retail area and an upstairs banquet space or apartment.

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    Mixed-Use Building with Freight Elevator
    Mixed-Use Building with Freight Elevator

    1415 W Genesee St, Syracuse, NY 13204

    Contact for pricing

    Two-story building includes a partially finished basement, storage attic, and a freight elevator from basement to attic.

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    Syracuse, NY Mixed-Use Properties Market Trends and Statistics

    Explore 72 mixed-use properties for sale in Syracuse, NY, showcased through 29 active listings on our real estate platform. These investment opportunities span a total of 483,345 square feet of properties for sale, with an estimated market value of $36,350,350.

    Sale prices for multi use buildings in Syracuse, NY start at $50,000, averaging $2,796,180, and reaching up to $22,657,450 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Live-work space 6

    Demographics Overview

    Population 229K
    Population Growth (5Y) -0.9%
    Median Household Income $59,936
    College Educated 33.4%

    High-Yield Neighborhoods for Investment

    Identify Syracuse submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    13210 $50K
    13209 $260K
    13206 $477K
    13202 $907.5K
    13204 $912.2K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Onondaga County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Onondaga County

    Office

    Residential Income

    Property Size Breakdown

    The majority of commercial real estate listings in Syracuse fall within the 100,000+ square foot range.

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    Most Searched ZIP Codes in Syracuse, NY

    • 13204
    • 13208
    • 13202
    • 13203
    • 13210
    • 13206
    • 13209
    • 13211
    • 13219

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