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    Syracuse, NY Medical Office Space for Sale

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    Jamesville, NY Camillus, NY Nedrow, NY Salina, NY East Syracuse, NY Fayetteville, NY Clay, NY Lafayette, NY
    9 properties
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    Single-Story Medical Office
    Updated: May 19
    Single-Story Medical Office

    105 N Main Street, Syracuse, NY 13212

    $400,000
    2,244 sqft 0.23 AC lot
    2,244 SF single‑level medical office building
    0.2317‑acre site with 15 dedicated parking spaces
    Interior includes exam rooms, private offices, optical retail, and laboratory space
    New asphalt roof installed in 2024
    Built in 1950 with a modern interior buildout
    View details
    Two-Story Medical Office
    Updated: Aug 8
    Two-Story Medical Office

    2800 Court Street, Syracuse, NY 13206

    $425,000
    4,538 sqft
    4,538 SF two‑story medical office building
    Flexible configuration for medical, professional office, or owner‑user occupancy
    Ample free on‑site parking
    Convenient access to I‑81 and I‑90
    Access to Downtown Syracuse
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    Renovated Medical Office Space
    Renovated Medical Office Space

    127-29 Seeley Road, Syracuse, NY 13224

    $355,000
    3,000 sqft

    Professionally renovated medical office with multiple suites, support areas, parking, and an accessible covered entrance.

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    See hot listings in Syracuse

    Scored against comparables nationwide. These are worth a look.

    Scored against comparables nationwide. These are worth a look.

    Cap Rate available after sign in
    Est. NOI available after sign in
    Local Demand available after sign in
    Two-Story Office Building with Garage
    Two-Story Office Building with Garage

    207 Chapel Dr, Syracuse, NY 13219

    $1,400,000
    8,205 sqft

    Commercial zoning and multiple private offices support professional-service use.

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    Multi-Story Office Building
    Multi-Story Office Building

    717 E Genesee Street, Syracuse, NY 13210

    Contact for pricing
    6,000 sqft

    Six-thousand-square-foot office building with private parking and renovated second-floor space.

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    Two-Story Medical Office Building
    Two-Story Medical Office Building

    2800 CT ST, Syracuse, NY 13208

    Contact for pricing
    4,538 sqft

    Vacant medical office property with separate upper- and lower-level layouts for healthcare and professional office operations.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    One-Story Medical Office Building
    One-Story Medical Office Building

    5792 Widewaters Parkway, Syracuse, NY 13214

    Contact for pricing
    29,432 sqft

    One-story medical office building with upgraded lobby and suite finishes, offering a vacant move-in-ready space.

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    Mixed-Use Property with Apartment
    Mixed-Use Property with Apartment

    1500 Grant Blvd, Syracuse, NY 13208

    Contact for pricing
    2,600 sqft

    Includes treatment rooms, imaging equipment, and a two-bedroom second-floor apartment.

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    Multi-Tenant Office Building For Sale
    Multi-Tenant Office Building For Sale

    716 James St, Syracuse, NY 13203

    Contact for pricing
    15,200 sqft

    Stand-alone office building with ample parking and convenient access.

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    Based on your search, we've compiled 46 Potential Opportunities for your consideration. Besides 9 Active listings in Syracuse, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 33 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Medical Office with Dental Equipment
    Medical Office with Dental Equipment

    7282 Oswego Road, Liverpool, NY 13090

    Contact for pricing
    2,621 sqft

    The existing dental setup includes equipment that remains with the property in its as-is condition.

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    Medical Office Suite
    Medical Office Suite

    5102 W Genesee Street, Camillus, NY 13031

    Contact for pricing
    1,200 sqft

    Existing dental configuration supports medical, professional, or general office use.

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    Medical Office Building with Parking
    Medical Office Building with Parking

    5639 W Genesee St, Camillus, NY 13031

    Contact for pricing
    10,000 sqft

    Medical office building offering a 2,000+/- SF space for lease and abundant parking.

    View details
    Medical Office Suite with Exam Rooms
    Medical Office Suite with Exam Rooms

    5100 W Taft Rd, Liverpool, NY 13088

    Contact for pricing
    1,168 sqft

    Third-floor medical suite includes a waiting room, reception, exam rooms, physician’s office, restroom, and kitchen.

    View details

    Off-Market Properties in Syracuse, NY

    Consider similar Off-Market properties in Syracuse, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    5008 Brittany Ln
    MEDICAL CLINIC

    5008 Brittany Ln, Syracuse, NY 13215

    Estimated value:
    $1,945,000
    70,668 sqft 5.35 AC lot
    View details
    504 Delaware St Sabine St
    MEDICAL CLINIC

    504 Delaware St Sabine St, Syracuse, NY 13204

    Estimated value:
    $270,000
    11,016 sqft 0.36 AC lot
    View details
    190 Intrepid Ln
    MEDICAL CLINIC

    190 Intrepid Ln, Syracuse, NY 13205-2545

    Estimated value:
    $4,055,000
    16,624 sqft 1.40 AC lot
    View details
    161 Intrepid Ln
    MEDICAL CLINIC

    161 Intrepid Ln, Syracuse, NY 13205-2548

    Estimated value:
    $305,000
    6,000 sqft 0.66 AC lot
    View details
    6227 Thompson Rd
    MEDICAL CLINIC

    6227 Thompson Rd, Syracuse, NY 13206-1405

    Estimated value:
    $335,000
    3,600 sqft 1.01 AC lot
    View details
    813 Fay Rd
    MEDICAL CLINIC

    813 Fay Rd, Syracuse, NY 13219-3009

    Estimated value:
    $1,605,000
    58,012 sqft 21.64 AC lot
    View details
    973 James St To Highland Ave
    MEDICAL CLINIC

    973 James St To Highland Ave, Syracuse, NY 13203

    Estimated value:
    $1,185,000
    53,509 sqft 2.39 AC lot
    View details
    2112 Erie E Blvd
    MEDICAL CLINIC

    2112 Erie E Blvd, Syracuse, NY 13224-1041

    Estimated value:
    $435,000
    15,511 sqft 1.14 AC lot
    View details
    5823 Widewaters Pkwy
    MEDICAL CLINIC

    5823 Widewaters Pkwy, Syracuse, NY 13214

    Estimated value:
    $1,140,000
    64,476 sqft 7.00 AC lot
    View details
    626-72 Salina S To Clinton St
    MEDICAL CLINIC

    626-72 Salina S To Clinton St, Syracuse, NY 13202

    Estimated value:
    $1,185,000
    79,763 sqft 2.59 AC lot
    View details
    228 Lafayette Rd
    MEDICAL CLINIC

    228 Lafayette Rd, Syracuse, NY 13205-2921

    Estimated value:
    $405,000
    11,388 sqft 2.59 AC lot
    View details
    5792 Widewaters Pkwy
    MEDICAL CLINIC

    5792 Widewaters Pkwy, Syracuse, NY 13214-1847

    Estimated value:
    $420,000
    15,128 sqft 5.13 AC lot
    View details
    2804 Brewerton Rd
    MEDICAL CLINIC

    2804 Brewerton Rd, North Syracuse, NY 13212-4102

    Estimated value:
    $285,000
    2,262 sqft 0.54 AC lot
    View details
    3606 James St
    MEDICAL CLINIC

    3606 James St, Syracuse, NY 13206-2448

    Estimated value:
    $300,000
    4,352 sqft 1.31 AC lot
    View details
    701 Erie E Blvd, Unit 9
    MEDICAL CLINIC

    701 Erie E Blvd, Syracuse, NY 13210-1014

    Unit 9
    Estimated value:
    $310,000
    6,897 sqft 0.46 AC lot
    View details

    Syracuse, NY Medical Office Space Market Trends and Statistics

    Explore 42 medical office space for sale in Syracuse, NY, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 75,757 square feet of properties for sale, with an estimated market value of $2,580,000.

    Sale prices for medical spaces in Syracuse, NY start at $355,000, averaging $645,000, and reaching up to $1,400,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 72
    Office buildings 45
    Medical Office Space 17
    Creative space 6

    Demographics Overview

    Population 229K
    Population Growth (5Y) -0.9%
    Median Household Income $59,936
    College Educated 33.4%

    High-Yield Neighborhoods for Investment

    Identify Syracuse submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    13224 $355K
    13212 $400K
    13206 $425K
    13219 $1.4M

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Onondaga County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Onondaga County

    Retail

    Office

    Residential Income

    Property Size Breakdown

    The majority of commercial real estate listings in Syracuse fall within the 100,000+ square foot range.

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