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    Syracuse, NY Medical Office Space for Sale

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    Nedrow, NY Camillus, NY Jamesville, NY
    North Syracuse Medical Office Building
    $400,000
    2,244 SF
    North Syracuse Medical Office Building

    105 N Main Street, Syracuse, NY 13212

    Well-maintained medical office in a high-growth area.
    • New roof installed in 2024 significantly reduces capital expenditure risk.
    • High‑visibility location on North Main Street with 15 dedicated parking spaces.
    • Professionally designed 2,244 SF medical office layout with reception, retail, exam rooms, offices, and lab.
    • Zoned for medical and professional office use, suitable for various practices.
    • Located in the rapidly growing Central New York economic corridor, near the Micron Technology facility.
    Updated: May 19
    View details
    Mixed-Use Building with Dental Practice
    $185,000
    2,600 SF
    Mixed-Use Building with Dental Practice

    1500 Grant Blvd and Mayar St, Syracuse, NY

    2600 SF building with dental practice and apartment.
    • Existing dental practice with 5 chairs and treatment rooms
    • Includes real estate with 2‑bedroom apartment
    • Zoned COM 1
    • Equipment Included: Panoramic & intraoral x‑ray machines
    • Approx. 2600 sf building with unfinished 3rd floor attic
    Updated: May 13, 2025
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    Well-Maintained Two-Story Office Building
    $1,695,000
    22,867 SF
    Well-Maintained Two-Story Office Building

    Two-story office building with basement and excellent onsite parking.

    5232 Witz Dr, N Syracuse, NY

    View details
    Based on your search, we've compiled 44 Potential Opportunities for your consideration. Besides 3 Active listings in Syracuse, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 33 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Homer Commercial Property on Corner Lot
    $649,900
    4,624 SF
    Homer Commercial Property on Corner Lot

    4,624 SF commercial property on 1.38 acres in Homer.

    82 Copeland Avenue, Homer, NY 13077

    View details
    Commercial Property on Corner Lot
    $649,900
    4,624 SF
    Commercial Property on Corner Lot

    4,624 sq ft commercial property on 1.38 acres.

    82 Copeland Ave, Homer, NY 13077

    View details
    Prime Corner Lot in Fulton
    $199,900
    1,305 SF
    Prime Corner Lot in Fulton

    High-traffic corner lot suitable for various commercial uses.

    203 E Broadway, Fulton, NY 13069

    View details
    Former Physician's Office For Sale
    $299,000
    7,032 SF
    Former Physician's Office For Sale

    Commercial property with features suited for professional endeavors.

    826 Holly Drive, Fulton, NY 13069

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Development Opportunity
    $1,900,000
    8,356 SF
    Prime Commercial Development Opportunity

    13-acre commercial property near Interstate 81 in West Monroe, NY.

    2931-39 State Route 49, West Monroe, NY 13167

    View details
    Commercial Land Near Oswego Hospital
    $299,000
    0.28 Acres
    Commercial Land Near Oswego Hospital

    Development opportunity near Oswego Hospital with high visibility and traffic.

    75-83 W Utica St, Oswego, NY 13126

    View details
    Commercial Lot on Route 332
    $125,000
    0.83 Acres
    Commercial Lot on Route 332

    Commercial lot suitable for office, medical, retail, or service uses.

    1386 Hathaway Drive, Farmington, NY 14425

    View details
    Commercially Zoned Land Opportunity
    $449,700
    21.92 Acres
    Commercially Zoned Land Opportunity

    21.92+/- acres with highway frontage, ideal for development.

    NYS Rt 17 and Old Rt 17, Harris, NY 12742

    View details

    Off-Market Properties in Syracuse, NY

    Consider similar Off-Market properties in Syracuse, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    5008 Brittany Ln

    5008 Brittany Ln

    MEDICAL CLINIC • 70,668 SF
    Value Estimation
    $1,945,000
    5008 Brittany Ln, Syracuse, NY 13215
    View details
    504 Delaware St Sabine St

    504 Delaware St Sabine St

    MEDICAL CLINIC • 11,016 SF
    Value Estimation by Request
    504 Delaware St Sabine St, Syracuse, NY 13204
    View details
    190 Intrepid Ln

    190 Intrepid Ln

    MEDICAL CLINIC • 16,624 SF
    Value Estimation
    $3,910,000
    190 Intrepid Ln, Syracuse, NY 13205-2545
    View details
    161 Intrepid Ln

    161 Intrepid Ln

    MEDICAL CLINIC • 6,000 SF
    Value Estimation by Request
    161 Intrepid Ln, Syracuse, NY 13205-2548
    View details
    6227 Thompson Rd

    6227 Thompson Rd

    MEDICAL CLINIC • 3,600 SF
    Value Estimation by Request
    6227 Thompson Rd, Syracuse, NY 13206-1405
    View details
    813 Fay Rd

    813 Fay Rd

    MEDICAL CLINIC • 58,012 SF
    Value Estimation
    $1,605,000
    813 Fay Rd, Syracuse, NY 13219-3009
    View details
    973 James St To Highland Ave

    973 James St To Highland Ave

    MEDICAL CLINIC • 53,509 SF
    Value Estimation
    $1,185,000
    973 James St To Highland Ave, Syracuse, NY 13203
    View details
    2112 Erie E Blvd

    2112 Erie E Blvd

    MEDICAL CLINIC • 15,511 SF
    Value Estimation by Request
    2112 Erie E Blvd, Syracuse, NY 13224-1041
    View details
    5823 Widewaters Pkwy

    5823 Widewaters Pkwy

    MEDICAL CLINIC • 64,476 SF
    Value Estimation
    $1,140,000
    5823 Widewaters Pkwy, Syracuse, NY 13214
    View details
    626-72 Salina S To Clinton St

    626-72 Salina S To Clinton St

    MEDICAL CLINIC • 79,763 SF
    Value Estimation
    $1,185,000
    626-72 Salina S To Clinton St, Syracuse, NY 13202
    View details
    228 Lafayette Rd

    228 Lafayette Rd

    MEDICAL CLINIC • 11,388 SF
    Value Estimation by Request
    228 Lafayette Rd, Syracuse, NY 13205-2921
    View details
    5792 Widewaters Pkwy

    5792 Widewaters Pkwy

    MEDICAL CLINIC • 15,128 SF
    Value Estimation by Request
    5792 Widewaters Pkwy, Syracuse, NY 13214-1847
    View details
    2804 Brewerton Rd

    2804 Brewerton Rd

    MEDICAL CLINIC • 2,262 SF
    Value Estimation by Request
    2804 Brewerton Rd, North Syracuse, NY 13212-4102
    View details
    3606 James St

    3606 James St

    MEDICAL CLINIC • 4,352 SF
    Value Estimation by Request
    3606 James St, Syracuse, NY 13206-2448
    View details
    701 Erie E Blvd, Unit 9

    701 Erie E Blvd, Unit 9

    MEDICAL CLINIC • 6,897 SF
    Value Estimation by Request
    701 Erie E Blvd, Syracuse, NY 13210-1014
    View details
    847 James St

    847 James St

    MEDICAL CLINIC • 27,732 SF
    Value Estimation
    $640,000
    847 James St, Syracuse, NY 13203-2504
    View details
    101 Seneca Tpke

    101 Seneca Tpke

    Individual retail properties • 16,986 SF
    Value Estimation by Request
    101 Seneca Tpke, Syracuse, NY 13205
    View details
    320 Pearl St

    320 Pearl St

    Medical Office Space • 17,160 SF
    Value Estimation by Request
    320 Pearl St, Syracuse, NY 13203
    View details
    333 Onondaga St

    333 Onondaga St

    Office Units • 7,500 SF
    Value Estimation by Request
    333 Onondaga St, Syracuse, NY 13202
    View details
    475 Irving Ave

    475 Irving Ave

    Medical Office Space • 95,000 SF
    Value Estimation by Request
    475 Irving Ave, Syracuse, NY 13210
    View details
    5957-6003 Salina St

    5957-6003 Salina St

    Restaurants
    Value Estimation by Request
    5957-6003 Salina St, Syracuse, NY 13205
    View details

    Syracuse, NY Medical Office Space Investment Opportunities Market Analysis

    Explore 36 medical office space for sale in Syracuse, NY, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 27,711 square feet of properties for sale, with an estimated market value of $2,280,000.

    Sale prices for medical spaces in Syracuse, NY start at $185,000, averaging $760,000, and reaching up to $1,695,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 63
    Office buildings 19
    Medical Office Space 12
    Creative space 4

    Property Size Breakdown

    The majority of commercial real estate listings in Syracuse fall within the 100,000+ square foot range.

    Demographics Overview

    Population 229K
    Population Growth (5Y) -0.9%
    Median Household Income $59,936
    College Educated 33.4%

    High-Yield Neighborhoods for Strategic Investment

    Identify Syracuse submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    13210 $450K
    13203 $899K

    Taxes & Financing

    Average Loan-to-Value 65.0%

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