Spartanburg, SC
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    Spartanburg, SC Office Units for Lease

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    Boiling Springs, SC Roebuck, SC Wellford, SC
    51 results
    Historic Mill Office Space Available
    $28 SF/Yr
    53,571 SF

    Historic Mill Office Space Available

    1802 Drayton Road, Suite 140B, Spartanburg, SC 29307

    Creative office space in a vibrant mixed-use community.

    • Located in Drayton Mills Marketplace, a successful adaptive‑reuse mixed‑use community.
    • ±3,934 SF office suite with restored historic mill character including exposed brick, high ceilings, and large windows.
    • Walkable access to restaurants, coffee shops, retail, fitness studio, and salons.
    • Connected to Drayton Mills’ trail network for walking, biking, and tenant events.
    • Flexible space suitable for office, creative studio, co‑working, or boutique professional services.
    Updated: Nov 25, 2025
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    Spartanburg Storefront Retail/Office Space
    $15 SF/Yr
    2,046 SF

    Spartanburg Storefront Retail/Office Space

    512 E Main St, Spartanburg, SC 29302

    Renovated 2,046 SF retail/office space in downtown Spartanburg.

    • High‑visibility location in Spartanburg's thriving downtown district with strong traffic count (±28,400 VPD).
    • Recently renovated ±2,046 SF storefront retail/office space suitable for a variety of uses.
    • Charming historic details, including exposed brick and tin ceilings.
    • Proximity to a diverse mix of businesses and restaurants.
    • Located in an area experiencing significant growth with ongoing developments (Project Core, Mary Black Trail extension, Fifth Third Park, Spartanburgers Stadium).
    Updated: Nov 21, 2025
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    6,000 SF Flex Building I-85
    Contact for pricing
    6,000 SF

    6,000 SF Flex Building I-85

    Flex building with lay-down yard fronting I-85.

    50 Fairview Church Rd, Spartanburg, SC 29303
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    Premier Office Suite For Rent
    $700/Mo
    425 SF

    Premier Office Suite For Rent

    Executive office suite in a premier location with ample natural light.

    1451 E Main St, Spartanburg, SC
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    Warehouse/Office Space Available For Lease
    $7 SF/Yr
    9,595 SF

    Warehouse/Office Space Available For Lease

    9,595 SF warehouse/office space with fenced laydown yard.

    1611 Union St, Spartanburg, SC
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    Spartanburg Flex Building For Lease
    Contact for pricing
    6,800 SF

    Spartanburg Flex Building For Lease

    Flex building with office and outdoor storage in Spartanburg.

    440 Southport Commerce Blvd, Spartanburg, SC 29306
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    Westside Office/Medical Space Available
    $16 SF/Yr
    5,461 SF

    Westside Office/Medical Space Available

    5461± sq ft office/medical space for rent.

    225 E Blackstock Rd, Spartanburg, SC
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    Office Space for Lease
    $2,500/Mo
    1,927 SF

    Office Space for Lease

    1,927 SF office space available for lease.

    517 E St John St, Spartanburg, SC
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    Downtown Office Space for Rent
    $23 SF/Yr
    2,500 SF

    Downtown Office Space for Rent

    Prime office space in Spartanburg's revitalized Central Business District.

    101 W Saint John St, Spartanburg, SC
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    Spartanburg Office Space Available
    $11 SF/Yr
    4,000 SF

    Spartanburg Office Space Available

    4,000 sq. ft. office space for rent.

    170 Camelot Dr, Spartanburg, SC
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    Spartanburg Office Space Available
    $25 SF/Yr
    444 SF

    Spartanburg Office Space Available

    Office space available for rent in Spartanburg, South Carolina.

    324 E Saint John St, Spartanburg, SC
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    Class A Office Space
    $21 SF/Yr
    2,963 SF

    Class A Office Space

    Professional office space on Spartanburg's Westside with high visibility.

    1460 John B White Sr Blvd, Spartanburg, SC
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    Renovated Office Space Available
    $20 SF/Yr
    1,500 SF

    Renovated Office Space Available

    Newly renovated office space in a high-visibility location.

    901 S Pine St, Spartanburg, SC
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    Southport Road Retail Opportunity
    Contact for pricing
    2,456 SF

    Southport Road Retail Opportunity

    2,456+/- SF building with excellent visibility and ample parking.

    2190 Southport Rd, Spartanburg, SC 29306
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    Spartanburg Flex Space For Lease
    $15 SF/Yr
    4,000 SF

    Spartanburg Flex Space For Lease

    Flex space featuring office and warehouse areas, near I-26.

    3211 Reidville Rd, Spartanburg, SC
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    Office Space Near I-26
    Contact for pricing
    3,600 SF

    Office Space Near I-26

    3,600+/- SF office space with laydown yard near I-26.

    208 Oak Forest Rd, Spartanburg, SC 29301
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    Downtown Spartanburg Retail/Office Space
    $23 SF/Yr
    1,525 SF

    Downtown Spartanburg Retail/Office Space

    Retail or office space with high visibility in downtown.

    178-182 E Main St, Spartanburg, SC
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    Spartanburg Office Space for Lease
    $16 SF/Yr
    1,200 SF

    Spartanburg Office Space for Lease

    Office space available near downtown Spartanburg with on-site parking.

    301 N Pine St, Spartanburg, SC
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    Spartanburg Westside Office Opportunity
    $14 SF/Yr
    6,059 SF

    Spartanburg Westside Office Opportunity

    Office space for rent near I-26 and Downtown Spartanburg.

    347-357 E Blackstock Rd, Spartanburg, SC
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    Spartanburg Office Space Available
    $17 SF/Yr
    3,200 SF

    Spartanburg Office Space Available

    Office space available for lease in Spartanburg, South Carolina.

    229 Magnolia St, Spartanburg, SC
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    Downtown Spartanburg Office Space
    $16 SF/Yr
    1,395 SF

    Downtown Spartanburg Office Space

    Office space in downtown Spartanburg with professional finishes.

    275 E Henry St, Spartanburg, SC
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    Class A Office Suite
    $23 SF/Yr
    2,268 SF

    Class A Office Suite

    Available office suite in Spartanburg's Point West Office Complex.

    775 Spartan Blvd, Spartanburg, SC
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    Office Space for Rent
    Contact for pricing

    Office Space for Rent

    Office space available for rent in Spartanburg, SC.

    Cedar Springs Rd, Spartanburg, SC 29302
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    Office Space Near Shopping Center
    $2,100/Mo
    1,866 SF

    Office Space Near Shopping Center

    Office space for rent across from Willow Place Shopping Center.

    1586 Skylyn Dr, Spartanburg, SC
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    Spartanburg, SC Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Spartanburg, SC with 51 listings featured on our commercial real estate exchange. The current inventory includes 162,103 square feet of properties with an estimated lease value of $707 /Mo.

    Estimated lease rates for Office Units in Spartanburg, SC begin at $7 SF/Yr, with an average of $19 SF/Yr and extend to $69 SF/Yr.
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