Office Units

Spartanburg, SC Office Units for Lease

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Renovated Furnished Office Units
Updated: Jun 21
Renovated Furnished Office Units

792 John B White Sr Boulevard, Spartanburg, SC 29306

$2,808/Mo
0.56 AC lot
1,230‑square‑foot furnished office property
Recently renovated with updated lighting, LVP, carpet, and contemporary finishes
Flexible office layout with central heating and central air
0.56‑acre site with parking lot and porch
Access to Interstate 26 and Interstate 85
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Modern Medical Office Space
Updated: Sep 4
Modern Medical Office Space

391 Serpentine Drive, Spartanburg, SC 29303

$1,156/Mo
4,387 sqft
Two available suites: 4,387 SF on the 1st floor and 3,956 SF on the 3rd floor
2nd‑floor surgery room with exhaust system already in place
Adjacent to Spartanburg Regional Medical Hospital
Approximately one mile to I‑585 via Hwy 9
232 on‑site parking spaces, including 29 covered spaces
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Industrial Flex Space with Two Buildings
Industrial Flex Space with Two Buildings

113 Ian Ct, Spartanburg, SC 29306

$12,500/Mo
12,500 sqft 1.95 AC lot

Two-building property combines office areas with warehouse space for flexible business operations.

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Flex Space with Conditioned Warehouse
Flex Space with Conditioned Warehouse

1095 Southport Rd, Spartanburg, SC 29306

$8 SF/Yr
24,000 sqft

Industrial property combining office accommodation with conditioned warehouse and manufacturing space.

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Spartanburg Storefront Retail/Office Space
Spartanburg Storefront Retail/Office Space

512 E Main St, Spartanburg, SC 29302

$15 SF/Yr
2,046 sqft

Renovated 2,046 SF retail/office space in downtown Spartanburg.

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Office Units with Dual Frontage
Office Units with Dual Frontage

846 WO Ezell Blvd, Spartanburg, SC 29301

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3,120 sqft

B4-zoned commercial space near downtown with exposure along two public streets.

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Historic Office Building for Rent
Historic Office Building for Rent

571 East Main Street, Spartanburg, SC 29302

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4,688 sqft 0.48 AC lot

Renovated historic building with multiple rooms, suited for professional office use, with street parking available.

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Class A Office Suite
Class A Office Suite

149B West Main Street, Spartanburg, SC 29306

$30 SF/Yr

Class A suite with private offices and flexible configuration, featuring top-floor views in downtown Morgan Square.

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Historic Spartanburg Mixed-Use Retail Space
Historic Spartanburg Mixed-Use Retail Space

174 E Main St, Spartanburg, SC 29306

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4,709 sqft

Retail space available in historic mixed-use building in downtown Spartanburg.

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Office Suite with Testing Facility
Office Suite with Testing Facility

105 Corporate Dr, Spartanburg, SC 29303

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1,350 sqft

Move-in-ready office suite with testing facility and a floor plan that can be modified to fit your operation.

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Office Suite on Main Street
Office Suite on Main Street

1948 E Main St, Spartanburg, SC 29307

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Office space on the East Main Street corridor with on-site parking for customers and employees.

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Westside Office/Medical Space Available
Westside Office/Medical Space Available

225 E Blackstock Rd, Spartanburg, SC

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5,461 sqft 0.94 AC lot

5461± sq ft office/medical space for rent.

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Spartanburg Office Space For Rent
Spartanburg Office Space For Rent

135 West Main Street, Spartanburg, SC

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1,700 sqft 0.08 AC lot

Office space available for rent in Spartanburg, SC.

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Office Suites in Spartanburg
Office Suites in Spartanburg

900 S Pine St, Spartanburg, SC

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1,218 sqft 0.68 AC lot

Office suites available in Spartanburg near downtown and amenities.

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Spartanburg Office Space For Rent
Spartanburg Office Space For Rent

2375 E Main St, Spartanburg, SC

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120 sqft 2.28 AC lot

Office space available for lease in Spartanburg, South Carolina.

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Spartanburg Office Space for Lease
Spartanburg Office Space for Lease

301 N Pine St, Spartanburg, SC

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1,200 sqft 0.35 AC lot

Office space available near downtown Spartanburg with on-site parking.

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Mixed-Use Building in Opportunity Zone
Mixed-Use Building in Opportunity Zone

500 W Main St, Spartanburg, SC

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1,683 sqft 7.26 AC lot

Retail, restaurant, office, and entertainment spaces for lease.

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Subdividable Two-Story Office Building
Subdividable Two-Story Office Building

201 Henry Pl, Spartanburg, SC 29306

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9,240 sqft 0.68 AC lot

Two-story office building with approximately 4,600 sq. ft. per level and flexible subdivision into four units.

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Class A Office Space
Class A Office Space

1460 John B White Sr Blvd, Spartanburg, SC

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2,963 sqft 3.65 AC lot

Professional office space on Spartanburg's Westside with high visibility.

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Spartanburg Office Space For Lease
Spartanburg Office Space For Lease

2500 Winchester Pl, Spartanburg, SC

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1,200 sqft 1.55 AC lot

1,200 SF office space in busy Westside location.

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Office Suites with Natural Light
Office Suites with Natural Light

2932 Reidville Rd, Spartanburg, SC 29301

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1,500 sqft

Three available office suites offer natural light, modern amenities, and ample parking for flexible business use.

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Office Space for Rent
Office Space for Rent

Cedar Springs Rd, Spartanburg, SC 29302

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Office space available for rent in Spartanburg, SC.

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Main Street Retail Opportunity
Main Street Retail Opportunity

194 E Main St, Spartanburg, SC

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2,300 sqft 0.07 AC lot

Retail and office space with high traffic frontage.

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High Visibility Commercial Space Available
High Visibility Commercial Space Available

846 W. O. Ezell Boulevard, Spartanburg, SC 29301

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3,120 SF office space with frontage on two streets.

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Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 24 Active listings in Spartanburg, SC, we suggest exploring alternatives.

Spartanburg, SC Office Units Lease Rates & Market Statistics

Explore 24 Office Units for lease in Spartanburg, SC on Realmo, a commercial real estate exchange covering the Spartanburg area. The current inventory totals 85,385 square feet of properties — an average of ~3,550 SF per listing.

Office Units lease rates in Spartanburg range from $8 SF/Yr at the entry level to $30 SF/Yr at the top of the market, averaging $16.25 SF/Yr. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $16.25 SF/Yr is 32% below the South Carolina state average of $24.02 SF/Yr.

Spartanburg accounts for 92% of the 26 office units currently available across Spartanburg County, where nearby markets include Boiling Springs and Wellford. Office Units make up 86% of the 28 Office Spaces currently for lease in Spartanburg, with asking rates in line with the citywide Office Spaces average. Also worth a look for tenants weighing alternatives: Office buildings (4 listings) elsewhere in the Spartanburg market.

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