Office Building

Greenville, SC Office Buildings for Lease

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39 properties
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Single-Story Freestanding Office Building
Updated: Jun 25
Single-Story Freestanding Office Building

1313A Miller Road, Greenville, SC 29607

$16.50 SF/Yr
4,000 sqft
±4,000 SF freestanding single‑story office building built in 1995
Layout includes eight private offices, a conference room, and an open bullpen area
Storage room with roll‑up door adds flexibility for office operations
Partially furnished office space for a faster setup
Ample on‑site parking
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Class A Office Building with Retail
Updated: Apr 21
Class A Office Building with Retail

3 Research Drive, Greenville, SC 29607

$1,208/Mo
1,208 sqft
Class A office building located on the CU‑ICAR Campus in Greenville, SC, right off I‑85
LEED Silver certified office building
Includes a small ground‑floor retail/office suite with exposure on Research Drive
Outdoor patio overlooking Research Drive
Ground‑floor signage opportunity for the retail space on Research Drive
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Downtown Greenville Office Space Available
Downtown Greenville Office Space Available

101 North Main Street, Greenville, SC 29601

$36.50 SF/Yr
11,085 sqft

Office space for rent in downtown Greenville with amenities.

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Fully Furnished Office Suite
Fully Furnished Office Suite

30 Patewood Drive, Greenville, SC 29615

$31 SF/Yr
7,915 sqft

Fully furnished office suite with on-site fitness center and tenant lounge, offering excellent exposure from I-385.

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Greenville Office Building For Rent
Greenville Office Building For Rent

84 Villa Road, Greenville, SC 29615

$21.50 SF/Yr
25,640 sqft 1.00 AC lot

Up to 25,640 SF available near I-385.

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Prime Office Space Near Museums
Prime Office Space Near Museums

301 College St, Greenville, SC 29601

$28 SF/Yr
130,000 sqft

Up to 130,000 SF available near Greenville's cultural hub.

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Suburban Office Park in Greenville
Suburban Office Park in Greenville

124 Verdae Blvd, Greenville, SC 29607

$22.50 SF/Yr
164,299 sqft

Office park in prime business district near shopping and restaurants.

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Greenville Office Space for Lease
Greenville Office Space for Lease

2000 Wade Hampton Boulevard, Greenville, SC 29615

$19 SF/Yr
188,900 sqft

Up to 188,900 SF available, near Downtown Greenville.

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Greenville Office Space For Rent
Greenville Office Space For Rent

1 Marcus Drive, Greenville, SC 29615

$16.50 SF/Yr
17,569 sqft

Office building with easy access to major roads and downtown.

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Single Story Office Building
Single Story Office Building

1100 Brookfield Parkway, Greenville, SC 29607

$18.50 SF/Yr
7,764 sqft

106,649 SF single-story office building with large floor plates.

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Prime Greenville Location with Amenities
Prime Greenville Location with Amenities

75 Beattie Place, Greenville, SC 29601

$39.50 SF/Yr
83,933 sqft

Office and retail spaces with on-site amenities in Greenville.

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Office Building
Office Building

400 Pelham Road, Greenville, SC 29615

Contact for pricing
6,536 sqft

Office property positioned near the Pelham Road and Haywood Road intersection.

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Move-In Ready Office Building
Move-In Ready Office Building

30 Pointe Cir, Greenville, SC 29615

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5,900 sqft

Move-in ready office building with reception, 16+ private offices, conference space, and four garage bays.

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Office Space with Drive-Thru Lanes
Office Space with Drive-Thru Lanes

937 N Pleasantburg Dr, Greenville, SC 29607

Contact for pricing
12,069 sqft

Office space with drive-thru lanes, 18 private offices, and 32 on-site parking spaces.

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Class A LEED Silver Office Building
Class A LEED Silver Office Building

110 East Court Street, Greenville, SC 29601

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5,024 sqft

Class A LEED Silver office building with flexible floor plates in downtown Greenville, SC.

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Greenville Office Space Available
Greenville Office Space Available

2000 Society Street, Greenville, SC 29615

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10,500 sqft

Office building with 10,500 square feet available for rent.

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Office Building with Rooftop Terrace
Office Building with Rooftop Terrace

1 Research Dr, Greenville, SC 29607

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13,390 sqft

Office building offering a rooftop terrace, fitness center, and tenant lounge with cafe.

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Downtown Class A Office Building
Downtown Class A Office Building

300 N Main Street, Greenville, SC 29601

$38.50 SF/Yr
5,414 sqft

Class A office building with attached parking garage in downtown.

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Pleasantburg Drive Office Building
Pleasantburg Drive Office Building

1934 N Pleasantburg Dr, Greenville, SC

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1,800 sqft 0.48 AC lot

1,800 SF office building for lease on 0.48 acres.

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Available Office Building in Greenville
Available Office Building in Greenville

50 Datastream Plaza, Greenville, SC 29605

Contact for pricing
124,836 sqft

124,836 SF office building for rent near I-85.

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Historic Downtown Greenville Office Space
Historic Downtown Greenville Office Space

130 S Main St, Greenville, SC 29601

$28.25 SF/Yr

Historic office building in downtown Greenville with modern amenities.

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Downtown Owner-Occupant Office Opportunity
Downtown Owner-Occupant Office Opportunity

504 Ferguson St, Greenville, SC

Contact for pricing
20,246 sqft 0.37 AC lot

Downtown office building with great amenities and parking options.

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Renovated Office Building, High Visibility
Renovated Office Building, High Visibility

1001 Keys Drive, Greenville, SC 29615

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35,500 sqft

Office building with recent renovations and high interstate visibility.

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Downtown Office Space
Downtown Office Space

14 S Main St, Greenville, SC 29601

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For rent at 14 S Main St, offering flexible office use in a central setting.

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Greenville, SC Office buildings Lease Rates & Market Statistics

Browse 39 Office buildings for lease in Greenville, SC on Realmo, a commercial real estate marketplace serving the Greenville area. The current inventory totals 1,134,697 square feet of properties — an average of ~29,100 SF per listing.

Office buildings lease rates in Greenville range from $12 SF/Yr at the entry level to $39.50 SF/Yr at the top of the market, averaging $25.25 SF/Yr. That's a 3x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $25.25 SF/Yr, the local average runs 9% above South Carolina's state average of $23.23 SF/Yr.

Greenville accounts for 85% of the 46 office buildings currently available across Greenville County, where nearby markets include Simpsonville and Greer. Office buildings make up 26% of the 149 Office Spaces currently for lease in Greenville, with asking rates in line with the citywide Office Spaces average. Tenants comparing options may also consider Office Units (101 listings) and Medical Office Space (6 listings) elsewhere in the Greenville market.

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