Syracuse, NY Office Properties & Spaces for Rent & Lease

Downtown Syracuse Office Space Available

$10,000 / Mo

39,245 SF

Downtown Syracuse Office Space Available

344 W Genesee St, Syracuse, NY 13202

Prime downtown Syracuse office space with parking available for lease.

Prime downtown Syracuse office space.
50‑car parking included.
Multiple suites available, some turnkey ready.
Suites can be combined for larger space to meet your needs.
Large windows with city views.

Updated: Oct 29, 2025

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$6 SF/Yr

70,696 SF

Green Hills Plaza: Lease Opportunity

5957-6003 Salina St, Syracuse, NY 13205

Versatile spaces, prime Onondaga location.

Multiple tenant retail, office, and restaurant space available for lease in Onondaga County.
Flexible layouts to accommodate various business types, including traditional office, creative office, coworking, executive office, and medical office uses.
High foot traffic and excellent visibility due to large anchor stores and vibrant community atmosphere.

Updated: Dec 11, 2024

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Thresh Professional Building: Syracuse Office Space

$12 SF/Yr

15,000 SF

Thresh Professional Building: Syracuse Office Space

Syracuse Office Suites: Free Month Available!

6443 Ridings Rd, Syracuse, NY 13206

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$17 SF/Yr

40,000 SF

Syracuse Creative Office Space

Modern Office Suites, Flexible Sizes

100 Elwood Davis Rd, Syracuse, NY 13212

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$18 SF/Yr

300,000 SF

One Park Place: Premier Office Space

Class A Office Suites, 2,500-80,000 SF

300 State St, Syracuse, NY 13202

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$18 SF/Yr

305,000 SF

One Lincoln Center Office Space

Syracuse, NY: Class A Office Suites

110 Fayette St, Syracuse, NY 13202

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Syracuse Office Space: Brooklawn Corporate Center

$15 SF/Yr

52,000 SF

Syracuse Office Space: Brooklawn Corporate Center

Class A Office Suites, Syracuse, NY

6712 Brooklawn Pkwy, Syracuse, NY 13211

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$12 SF/Yr

110,000 SF

Syracuse Executive Office Space

Prestigious Syracuse office suites, 1,409-15,000 sq ft.

224 Harrison St, Syracuse, NY 13202

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$15 SF/Yr

21,160 SF

Prime North Syracuse Office Space

Modern Office Suites, Flexible Sizes Available

7293 Buckley Rd, North Syracuse, NY 13212

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$22 SF/Yr

30,000 SF

Armory Square Office Space Available

Syracuse, NY: Prime Office & Retail Space

183 Walton St, Syracuse, NY 13202

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21,965 SF

Prime Syracuse CBD Office Space

Executive Suites, 9,349-12,616 SF Available

2363 James St, Syracuse, NY 13206

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$15 SF/Yr

1,000 SF

Downtown Syracuse Retail Space

Prime Retail/Office, 1,000 SF Available

217 Montgomery St, Syracuse, NY 13202

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$225 SF/Yr

1,600 SF

Herald Place Office Space for Lease

Updated 1,600 sq ft Office in Syracuse

221 Herald Pl, Syracuse, NY 13202

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$17 SF/Yr

6,000 SF

Sherwood Office Park Suite 140

Prime Office Space, Syracuse, NY

6704 Buckley Rd, Syracuse, NY 13212

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$20 SF/Yr

173,513 SF

State Tower Office Suites

Prestigious Class A office space, downtown Syracuse.

109 Warren St, Syracuse, NY 13202

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$12 SF/Yr

140,000 SF

University Building Office Suites

Historic Charm, Modern Amenities, CBD Location

120 Washington St, Syracuse, NY 13202

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477,610 SF

Syracuse Office Space Available

Prime Downtown Syracuse Office, Retail Space

441 Salina St, Syracuse, NY 13202

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$14 SF/Yr

15,200 SF

James Street Office Building

15,200 SF Office Space Available

716 James St, Syracuse, NY 13203

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$180 SF/Yr

3,000 SF

Downtown Syracuse Office Space

Prime 3,000 sq ft Office in Syracuse, NY

216 Genesee St, Syracuse, NY 13202

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$16 SF/Yr

21,422 SF

Prime Office Building, N. Syracuse

Free-standing, 21,422 SF, 110 parking spaces

125 Elwood Davis Rd, Syracuse, NY 13212

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$8 SF/Yr

5,500 SF

Acropolis Center: Syracuse Office Space

Prime Syracuse Office, 5,500 SF Available

115 Jefferson St, Syracuse, NY 13202

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$4,200 / Mo

3,600 SF

Syracuse Commercial Gem: 3,600 SF

Versatile office space near Route 81.

2500 Brewerton Rd, Mattydale, NY 13211

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$25 SF/Yr

2,200 SF

Downtown Syracuse Retail Space

Prime location, multiple suites available

333 Salina St, Syracuse, NY 13202

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$12 SF/Yr

6,400 SF

North Syracuse Office Space

Prime Office Suites, Newly Renovated

109 Taft Rd, North Syracuse, NY 13212

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Syracuse, NY Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in Syracuse, NY with 119 listings featured on our commercial real estate exchange. The current inventory includes 107,541,363,600 square feet of properties with an estimated lease value of $1,422 /Mo.

Estimated lease rates for Office Properties & Spaces in Syracuse, NY begin at $3 SF/Yr, with an average of $20 SF/Yr and extend to $225 SF/Yr.

Syracuse, NY Office Properties & Spaces for Lease

Downtown Syracuse Office Space Available

Prime downtown Syracuse office space with parking available for lease.

Green Hills Plaza: Lease Opportunity

Versatile spaces, prime Onondaga location.

Thresh Professional Building: Syracuse Office Space

Syracuse Creative Office Space

One Park Place: Premier Office Space

One Lincoln Center Office Space

Syracuse Office Space: Brooklawn Corporate Center

Syracuse Executive Office Space

Prime North Syracuse Office Space

Armory Square Office Space Available

Prime Syracuse CBD Office Space

Downtown Syracuse Retail Space

Herald Place Office Space for Lease

Sherwood Office Park Suite 140

State Tower Office Suites

University Building Office Suites

Syracuse Office Space Available

James Street Office Building

Downtown Syracuse Office Space

Prime Office Building, N. Syracuse

Acropolis Center: Syracuse Office Space

Syracuse Commercial Gem: 3,600 SF

Downtown Syracuse Retail Space

North Syracuse Office Space

Syracuse, NY Office Properties & Spaces Leasing Opportunities Market Analysis

Browse Office Properties & Spaces for Lease Near Syracuse, NY

Popular Searches in Syracuse, NY

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Syracuse, NY Office Properties & Spaces for Lease

Downtown Syracuse Office Space Available

Prime downtown Syracuse office space with parking available for lease.

Green Hills Plaza: Lease Opportunity

Versatile spaces, prime Onondaga location.

Thresh Professional Building: Syracuse Office Space

Syracuse Creative Office Space

One Park Place: Premier Office Space

One Lincoln Center Office Space

Syracuse Office Space: Brooklawn Corporate Center

Syracuse Executive Office Space

Prime North Syracuse Office Space

Armory Square Office Space Available

Prime Syracuse CBD Office Space

Downtown Syracuse Retail Space

Herald Place Office Space for Lease

Sherwood Office Park Suite 140

State Tower Office Suites

University Building Office Suites

Syracuse Office Space Available

James Street Office Building

Downtown Syracuse Office Space

Prime Office Building, N. Syracuse

Acropolis Center: Syracuse Office Space

Syracuse Commercial Gem: 3,600 SF

Downtown Syracuse Retail Space

North Syracuse Office Space

Syracuse, NY Office Properties & Spaces Leasing Opportunities Market Analysis

Browse Office Properties & Spaces for Lease Near Syracuse, NY

Popular Searches in Syracuse, NY

Popular Categories

Most Searched ZIP Codes in Syracuse, NY

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