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    Syracuse, NY Office Properties & Spaces for Lease

    57 results
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    Syracuse Office Space Sublease
    $5,000 /Mo
    37,112 SF

    Syracuse Office Space Sublease

    422 W Onondaga Street, Syracuse, NY 13202

    Office space for sublease, all-inclusive rent covers utilities and maintenance.

    • All‑inclusive $5,000 monthly rate covers rent, utilities, parking, maintenance, and more.
    • Sublease term extends through October 31, 2029.
    • Ideal for a wide range of professional or office activities.
    • Well‑maintained and professionally managed environment.
    • Includes essential services like snow plowing/removal and groundskeeping.
    Updated: Mar 5
    View details
    Downtown Syracuse Office Space Available
    $10,000 /Mo
    39,245 SF

    Downtown Syracuse Office Space Available

    344 W Genesee Street, Syracuse, NY 13202

    Prime downtown Syracuse office space with parking available for lease.

    • Prime downtown Syracuse office space.
    • 50‑car parking included.
    • Multiple suites available, some turnkey ready.
    • Suites can be combined for larger space to meet your needs.
    • Large windows with city views.
    Updated: Oct 28, 2025
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    Medical Office Space Available
    $19 SF/Yr
    5,126 SF

    Medical Office Space Available

    5,126 SF medical office suite for lease.

    792 North Main Street, North Syracuse, NY 13212
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    Creative Office Space in Syracuse
    $16 SF/Yr
    2,500 SF

    Creative Office Space in Syracuse

    Modern office space with natural light and flexible floor plans.

    200 S Geddes St, Syracuse, NY
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    Iconic Mixed-Use State Tower
    $18 SF/Yr
    23,201 SF

    Iconic Mixed-Use State Tower

    Mixed-use property with office, residential, and retail spaces available.

    109 South Warren Street, Syracuse, NY 13202
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    Syracuse Office Space Available
    $13 SF/Yr
    2,600 SF

    Syracuse Office Space Available

    Office space available for rent in Syracuse, New York.

    208 S Warren St, Syracuse, NY
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    Prime Armory Square Office Space
    $12 SF/Yr
    2,500 SF

    Prime Armory Square Office Space

    Commercial office space for lease in the heart of Armory Square.

    316 S Clinton St, Syracuse, NY
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    Downtown Syracuse Office Building
    Contact for pricing
    15,000 SF

    Downtown Syracuse Office Building

    15,163 SF office building in downtown Syracuse for lease.

    716 James Street, Syracuse, NY 13203
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    Restored Office Building in Syracuse
    $18 SF/Yr
    15,000 SF

    Restored Office Building in Syracuse

    Restored office building with parking near Armory Square.

    358 W Jefferson St, Syracuse, NY
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    Downtown Syracuse Office Space Available
    $14 SF/Yr
    4,039 SF

    Downtown Syracuse Office Space Available

    4,039 SF office space with city views.

    100-120 Madison St, Syracuse, NY
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    Office Space Available For Rent
    $18 SF/Yr
    1,100 SF

    Office Space Available For Rent

    Office space for rent at 709 Erie Blvd W.

    709 Erie Blvd W, Syracuse, NY
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    Class A Office Space
    $26 SF/Yr
    5,500 SF

    Class A Office Space

    Up to 5,500 SF office space for rent.

    127 Solar St, Syracuse, NY
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    Syracuse Office Space Available
    $16 SF/Yr
    1,295 SF

    Syracuse Office Space Available

    Office space available for lease in Syracuse, New York.

    451 S Main St, Syracuse, NY
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    Downtown Office Space Available
    $15 SF/Yr
    26,000 SF

    Downtown Office Space Available

    Up to 26,000 SF available in downtown Syracuse.

    677 S Salina St, Syracuse, NY
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    Modern Office Space with Amenities
    Contact for pricing
    4,000 SF

    Modern Office Space with Amenities

    Office space with parking, security, fitness center, and spa.

    357 S Warren St, Syracuse, NY
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    Renovated Office Building with Parking
    Contact for pricing
    6,300 SF

    Renovated Office Building with Parking

    Downtown office building with on-site parking and renovated interior.

    506 E Washington St, Syracuse, NY 13202
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    Retail/Office Suites on James Street
    Contact for pricing
    850 SF

    Retail/Office Suites on James Street

    Three suites available with high visibility and modern finishes.

    3001-3023 James St, Syracuse, NY
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    Medical Building with Flexible Suites
    Contact for pricing
    5,000 SF

    Medical Building with Flexible Suites

    Professional medical building with suites available for lease.

    2112 Erie Blvd E, Syracuse, NY
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    Furnished Office Space Near Universities
    Contact for pricing
    400 SF

    Furnished Office Space Near Universities

    Furnished office space with private entrance and on-site parking.

    18 Arbor Ln, Syracuse, NY
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    Class A Office Space Available
    $17 SF/Yr
    3,150 SF

    Class A Office Space Available

    3,150 SF office suite with private offices and conference room.

    6706 Buckley Rd, Syracuse, NY
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    Retail Space on Thompson Road
    Contact for pricing
    9,068 SF

    Retail Space on Thompson Road

    9,068 SF retail, office, and warehouse space for lease.

    6361 Thompson Rd, Syracuse, NY
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    Renovated Space Near Syracuse University
    $25 SF/Yr
    3,693 SF

    Renovated Space Near Syracuse University

    Renovated space suitable for retail, office, or restaurant use.

    East Fayette St 900, Syracuse, NY
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    Syracuse Office Space Available
    $15 SF/Yr
    1,500 SF

    Syracuse Office Space Available

    Office space available for lease in Syracuse, New York.

    530 S Clinton St, Syracuse, NY
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    Furnished Office Space Available
    $8 SF/Yr
    35,000 SF

    Furnished Office Space Available

    Sublease office space with free parking and storage.

    704 Marcellus St, Syracuse, NY
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    Syracuse, NY Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Syracuse, NY with 57 listings featured on our commercial real estate exchange. The current inventory includes 5,949,381,240 square feet of properties with an estimated lease value of $119 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Syracuse, NY begin at $1.62 SF/Yr, with an average of $11 SF/Yr and extend to $19 SF/Yr.
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    Browse Office properties & Spaces for Lease Near Syracuse, NY

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    Most Searched ZIP Codes in Syracuse, NY

    • 13202
    • 13212
    • 13203
    • 13204
    • 13206
    • 13211

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