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Portland, ME Office Spaces for Lease

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South Portland, ME Falmouth, ME Scarborough, ME Westbrook, ME Yarmouth, ME Freeport, ME Windham, ME Saco, ME
62 properties
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Downtown Office Suite with Natural Light
Updated: Jun 2
Downtown Office Suite with Natural Light

5 Milk Street, Portland, ME 04101

$15.50 SF/Yr
4,473 sqft
4,473± SF modern office space in a historic brick and beam building
Exceptional natural light throughout
Street‑level private entrance
Layout includes a mix of private offices, open area, and storage space
Located in Old Port, with nearby access to highway
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Updated Office Unit with Hardwood Floors
Updated: Aug 8
Updated Office Unit with Hardwood Floors

22 Monument Square, Portland, ME 04101

$950/Mo
524 sqft
524± SF office unit available for lease
Hardwood flooring and high plaster ceilings
New LED pendant lighting
Views of Monument Square
Updated office space in downtown Portland
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First-Floor Office Space
First-Floor Office Space

503-509 Forest Avenue, Portland, ME 04101

$12 SF/Yr
4,000 sqft

First-floor office space is available for lease in a commercial building.

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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
Turn-Key Office Suite
Turn-Key Office Suite

120 Exchange Street, Suite 310, Portland, ME 04101

$18 SF/Yr
10,766 sqft

Recently remodeled, turn-key Class A office suite with parking available at a landlord-owned garage.

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Renovated Retail/Office Space Available
Renovated Retail/Office Space Available

503-509 Forest Avenue, Portland, ME 04101

$12 SF/Yr
6,313 sqft

Up to 6,313 square feet of contiguous space for lease.

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Downtown Office Space
Downtown Office Space

15 Franklin St, Portland, ME 04101

$19.75 SF/Yr
13,492 sqft

Office suites available in a downtown Portland building with on-site parking.

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Retail/Office Building Space Available
Retail/Office Building Space Available

891 Washington Avenue, Portland, ME 04101

$16 SF/Yr
27,600 sqft

Retail or office space available for lease in Portland, Maine.

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Office/Retail Space Available
Office/Retail Space Available

901 Washington Avenue, Portland, ME 04101

$10 SF/Yr
32,289 sqft

Office or retail space available for lease.

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High-Visibility Retail/Office Suite
High-Visibility Retail/Office Suite

94 Auburn Street, Suite 101, Portland, ME 04103

$1,995/Mo

Suite 101 offers high-visibility retail and office space near Northgate Plaza with easy access to major highways.

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Flexible Workspace Solutions at ME, Portland - Hutchins Dr. Contact us today to book a tour!
Flexible Workspace Solutions at ME, Portland - Hutchins Dr. Contact us today to book a tour!

41 1St St, Unit 3, Portland, ME 04102

16 available spaces from 11 to 1,958 sqft
$129-$17,335/Mo per office

Flexible workspace in ME, Portland - Hutchins Dr. Book a tour & get info

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Turnkey Medical Office Suite
Turnkey Medical Office Suite

94 Washington Avenue, Portland, ME 04101

$1,800/Mo

Fully furnished dental-medical suite with treatment rooms, office, and reception, plus on-site parking for non-profit users.

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Renovated Office Suite in Portland
Renovated Office Suite in Portland

100 Middle Street, Suite 400, Portland, ME 04101

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4,886 sqft

Class A office space in downtown Portland with on-site parking.

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Renovated Waterfront Office Building
Renovated Waterfront Office Building

254 Commercial St, Portland, ME 04101

$650/Mo

Historic Class A office space with harbor views.

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Newly Renovated Corner Office Suite
Newly Renovated Corner Office Suite

100 Middle St, Portland, ME 04101

$28 SF/Yr

Newly renovated 4,886+/- SF office suite in a Class A building with on-site parking.

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Historic Office Suite Rentals
Historic Office Suite Rentals

22 Free Street, Portland, ME 04101

$26 SF/Yr

Office suites are available in multiple sizes, ranging from approximately 724 to 3,181 SF, for lease in Portland’s Old Port.

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Flex Space with Mezzanine Office
Flex Space with Mezzanine Office

65 Hanover St, Portland, ME 04101

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1,007 sqft

Bright flex office/retail unit with large glass entry, a rear mezzanine office, and two dedicated on-site parking spaces.

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Old Port Third Floor Office
Old Port Third Floor Office

130 Middle St, Portland, ME

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8,153 sqft 1.32 AC lot

Full third floor office space in the Old Port.

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Class A Office/Retail Space
Class A Office/Retail Space

190 Middle St, Portland, ME

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10,502 sqft 0.56 AC lot

10,502± SF Class A space centrally located in Portland, ME.

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Office
Office

1 Davis Farm Rd, Portland, ME 04103

$9 SF/Yr

Office buildings

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Downtown Office Suites
Downtown Office Suites

188 State St, Portland, ME 04102

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98 sqft

Office suites include a shared waiting area, conference room, restrooms, and kitchenette, with ample windowed natural light.

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Office Space for Lease
Office Space for Lease

130 Middle Street, Portland, ME 04101

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Office space offered for rent at 130 Middle Street in Portland, Maine.

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Downtown Portland Office Suites
Downtown Portland Office Suites

188 State St, Portland, ME 04101

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650 sqft 0.09 AC lot

Office suites for lease in downtown Portland with shared amenities.

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Office Space for Lease
Office Space for Lease

85 Exchange St, Portland, ME 04101

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Office space available for lease at 85 Exchange Street in Portland, Maine.

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Portland Office & Coworking Space
Portland Office & Coworking Space

41 Hutchins Dr, Building 3, 1st & 2nd Floor, Portland, ME 04102

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Professional coworking and office spaces in Portland, Maine's largest city.

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Portland, ME Office Spaces Lease Rates & Market Statistics

Browse 62 Office Spaces for lease in Portland, ME on Realmo, a commercial real estate marketplace serving the Portland area. The current inventory totals 614,107 square feet of properties — an average of ~9,900 SF per listing.

Asking lease rates for Office Spaces in Portland start at $9 SF/Yr, average $17.09 SF/Yr, and reach $28 SF/Yr at the top of the market. That's a 3x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $17.09 SF/Yr, the local average runs 21% below Maine's state average of $21.62 SF/Yr.

Portland accounts for 63% of the 98 office spaces currently available across Cumberland County, where nearby markets include South Portland and Scarborough. By space type, the market includes 38 office units, 11 office buildings and 9 other office properties — other office properties typically offer the lowest entry point, while office units command the highest rates.

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