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    Portland, ME Office Units for Lease

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    South Portland, ME Cape Elizabeth, ME Falmouth, ME
    87 results
    Downtown Portland Office Space Available
    $24 SF/Yr
    5,081 SF

    Downtown Portland Office Space Available

    48 Free St, Portland, ME 4101

    Full floor office suites for lease in Portland's financial district.

    • Excellent location in Portland's financial district, steps from Old Port and waterfront.
    • High Walkability Score of 96.
    • Rare opportunity to occupy a full floor in a Downtown Portland building.
    • Surface lot parking provides direct access to the building.
    • Suites available from 1,610± to 5,786± SF.
    Updated: Nov 25, 2025
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    Renovated Waterfront Office with Harbor Views
    $650/Mo
    460 SF

    Renovated Waterfront Office with Harbor Views

    254 Commercial St, Portland, ME 4101

    Historic Class A office space with exposed beams and brick.

    • Prime waterfront location with sweeping views of Portland Harbor.
    • Fully renovated, historic Class A office building.
    • New energy‑efficient windows, HVAC systems, and upgraded lighting.
    • Prestigious tenant roster including Pierce Atwood and Ocean Renewable Power Company.
    • Excellent Walk Score of 87.
    Updated: Nov 11, 2025
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    Renovated Office Space in Portland
    $18 SF/Yr
    2,445 SF

    Renovated Office Space in Portland

    Second floor office space for lease in Portland's Financial District.

    50 Monument Sq, Portland, ME 4101
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    Historic Old Port Office Space
    $18 SF/Yr
    6,891 SF

    Historic Old Port Office Space

    Office space in historic rehab with high ceilings and windows.

    129-131 Middle St, Portland, ME
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    Historic Office Space For Rent
    $30 SF/Yr
    2,800 SF

    Historic Office Space For Rent

    2,800 SF office space in historic Roundhouse complex.

    125 Presumpscot St, Portland, ME 4103
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    Old Port Third Floor Office
    $25 SF/Yr
    8,153 SF

    Old Port Third Floor Office

    Full third floor office space in the Old Port.

    130 Middle St, Portland, ME
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    Historic Office Space For Lease
    $14 SF/Yr
    3,700 SF

    Historic Office Space For Lease

    Historic office space available for lease in former firehouse.

    19 Arbor St, Portland, ME
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    Portland Retail/Office Space For Sale
    $18 SF/Yr
    9,045 SF

    Portland Retail/Office Space For Sale

    Retail and office spaces available in Portland, Maine.

    550 Washington Ave, Portland, ME
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    Fore Street Office Space Available
    $23 SF/Yr
    2,618 SF

    Fore Street Office Space Available

    Office space for lease in vibrant Portland waterfront area.

    167 Fore St, Portland, ME
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    Modern Office Suites in Portland
    $19 SF/Yr
    1,100 SF

    Modern Office Suites in Portland

    Move-in ready office suites near Downtown and Old Port.

    53 York, Portland, ME
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    Bayside Office Suite For Rent
    $17 SF/Yr
    1,059 SF

    Bayside Office Suite For Rent

    Office suite in Bayside with convenient access and parking.

    175 Lancaster St, Portland, ME
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    Turnkey Dental Suite For Lease
    $1,800/Mo
    1,350 SF

    Turnkey Dental Suite For Lease

    Turnkey dental suite with furniture, fixtures, and equipment in place.

    94 Washington Ave, Portland, ME
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    Renovated Office Suite For Lease
    $2,200/Mo
    750 SF

    Renovated Office Suite For Lease

    750± SF renovated office suite in North Deering, Portland.

    Washington Ave 1321, Portland, ME
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    Historic Office Space in Portland
    $24 SF/Yr
    1,189 SF

    Historic Office Space in Portland

    Distinguished office space in Portland's vibrant Old Port district.

    24 City Ctr, Portland, ME
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    Historic Office Space with Views
    $25 SF/Yr
    4,250 SF

    Historic Office Space with Views

    Office suites available in historic brick building with water views.

    100 Commercial St, Portland, ME 4102
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    Updated Office Suites in Old Port
    $21 SF/Yr
    2,441 SF

    Updated Office Suites in Old Port

    Bright, updated office spaces in Portland's desirable Old Port.

    14 York St, Portland, ME 4101
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    Waterfront Office Space Available
    $24 SF/Yr
    805 SF

    Waterfront Office Space Available

    805± SF office suite with waterfront views for lease.

    2 Portland Fish Pier, Portland, ME
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    Downtown Portland Office Space Available
    $17 SF/Yr
    984 SF

    Downtown Portland Office Space Available

    Multiple office spaces for lease in historic downtown Portland.

    Congress St 415, Portland, ME
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    Portland Office Space For Lease
    $14 SF/Yr
    3,000 SF

    Portland Office Space For Lease

    3,000 SF office space suitable for professional services.

    973 Forest Ave, Portland, ME
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    Class A Office/Retail Space
    $23 SF/Yr
    10,502 SF

    Class A Office/Retail Space

    10,502± SF Class A space centrally located in Portland, ME.

    190 Middle St, Portland, ME
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    Renovated Office Space in Portland
    $22 SF/Yr
    10,308 SF

    Renovated Office Space in Portland

    10,308±SF office suite in iconic mixed-use building for lease.

    55-75 Washington Ave, Portland, ME
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    Warehouse and Office Space Available
    $10 SF/Yr
    31,900 SF

    Warehouse and Office Space Available

    27,500 SF warehouse and 4,400 SF office space for lease.

    250 Read St, Portland, ME
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    Bayside Office Space For Lease
    $12 SF/Yr
    33,074 SF

    Bayside Office Space For Lease

    Up to 33,074 SF of office space available for lease.

    165 Lancaster St, Portland, ME
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    Historic Old Port Office Space
    $24 SF/Yr
    905 SF

    Historic Old Port Office Space

    Office suites in historic building, walking distance to amenities.

    237 Commercial St, Portland, ME
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    Portland, ME Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Portland, ME with 87 listings featured on our commercial real estate exchange. The current inventory includes 400,354 square feet of properties with an estimated lease value of $1,349 /Mo.

    Estimated lease rates for Office Units in Portland, ME begin at $4 SF/Yr, with an average of $19 SF/Yr and extend to $60 SF/Yr.
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    Most Searched ZIP Codes in Portland, ME

    • 04101
    • 04103
    • 04102

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