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    St Lucie County, FL Office Properties & Spaces for Lease

    100 results
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    Move-in Ready Executive Office Suite
    $2,451 /Mo
    998 SF

    Move-in Ready Executive Office Suite

    2100 SE Hillmoor Dr, Port St Lucie, FL 34952

    First floor office suite near HCA Florida St. Lucie Hospital.

    • Move‑in ready condition
    • Prime location near HCA Florida St. Lucie Hospital
    • Functional layout featuring a waiting room, reception area, kitchen, and four private offices
    • Located in a high‑demand medical/professional corridor
    • Strong residential density in surrounding area
    Last Update: Dec 4
    View details
    Port Saint Lucie Office/Warehouse Condo
    $1,450 /Mo
    10,019 SF

    Port Saint Lucie Office/Warehouse Condo

    1260 SE Industrial Blvd, Port Saint Lucie, FL 34952

    Office and warehouse space available for lease in Port Saint Lucie.

    • Two units available (1260 and 1288), each 1000 sf.
    • Combination office (25% air conditioned) and warehouse (75%) space.
    • Move‑in requires only one month's deposit.
    • Concrete flooring in warehouse area.
    • Built in 2003.
    Last Update: Nov 24
    View details
    Landmark Office Building in Fort Pierce
    $16 SF/Yr
    56,628 SF

    Landmark Office Building in Fort Pierce

    5,400 SF office space available for lease.
    2222 Colonial Rd, Fort Pierce, FL 34950
    View details
    Freestanding Building on US Highway
    $26 SF/Yr
    46,609 SF

    Freestanding Building on US Highway

    General Commercial zoning ideal for retail, medical, or restaurant.
    10244 S Us Highway 1, Port St Lucie, FL 34952
    View details
    Fort Pierce Office Space Available
    $16 SF/Yr
    18,228 SF

    Fort Pierce Office Space Available

    2,400 SF office space for lease in Fort Pierce.
    2222 Colonial Rd, Fort Pierce, FL 34950
    View details
    Profitable Office Space with Tenants
    $275,000

    Profitable Office Space with Tenants

    Turnkey office property with long-term tenants and immediate cash flow.
    544 NW University Blvd Blvd, Port Saint Lucie, FL 34986
    View details
    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Modern flex office spaces for lease in Fort Pierce, Florida.
    3801 Oleander Ave, Fort Pierce, FL 34982
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    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Flexible leasing options in a busy industrial corridor.
    3801 Oleander Ave, Fort Pierce, FL 34982
    View details
    Modern Flex Office Spaces
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces

    Versatile flex spaces ideal for various businesses, move-in ready.
    3801 Oleander Ave, Fort Pierce, FL 34982
    View details
    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Modern flex office spaces for lease in Fort Pierce, Florida.
    3801 Oleander Ave, Fort Pierce, FL 34982
    View details
    Medical Office Space For Rent
    $24 SF/Yr
    998 SF

    Medical Office Space For Rent

    Updated medical office space available for rent in Port St. Lucie.
    1801 SE Hillmoor Dr, Port St Lucie, FL 34952
    View details
    Port St. Lucie Executive Office
    $1,527 /Mo
    998 SF

    Port St. Lucie Executive Office

    Executive office suite in Port St. Lucie medical corridor.
    2100 SE Hillmoor Dr, Port St Lucie, FL 34952
    View details
    Medical Office Near Lawnwood Hospital
    $500,000

    Medical Office Near Lawnwood Hospital

    Turnkey medical office space in Fort Pierce healthcare corridor.
    1801 S 23Rd St, Fort Pierce, FL 34950
    View details
    Mixed-Use Commercial Property in Fort Pierce
    $997,321
    392,040 SF

    Mixed-Use Commercial Property in Fort Pierce

    High-traffic location near I-95 and downtown Fort Pierce.
    3328 Orange Ave, Fort Pierce, FL 34947
    View details
    Renovated Office Building Near Hospital
    $2,500 /Mo
    38,999 SF

    Renovated Office Building Near Hospital

    Recently renovated 1,200 sqft office building near HCA Hospital.
    2502 Acorn St, Fort Pierce, FL 34947
    View details
    Medical Co-working Space Available
    $5,416 /Mo
    63,341 SF

    Medical Co-working Space Available

    Co-working space in established medical hub near major hospitals.
    2401 Frist Blvd, Fort Pierce, FL 34950
    View details
    Class A Office Suite
    $2,287 /Mo
    998 SF

    Class A Office Suite

    Professional office suite with private offices and open space.
    2100 SE Hillmoor Dr, Port St Lucie, FL 34952
    View details
    Fort Pierce Office/Warehouse on US 1
    $10,000 /Mo
    4,648 SF

    Fort Pierce Office/Warehouse on US 1

    4-acre commercial property with office, retail, and warehouse space.
    3535 Old Dixie Hwy, Fort Pierce, FL 34946
    View details
    Fort Pierce Office/Warehouse Opportunity
    $2,200,000
    59,677 SF

    Fort Pierce Office/Warehouse Opportunity

    Class B office building with flexible layouts in Fort Pierce.
    3030 N 25Th St, Fort Pierce, FL 34946
    View details
    Prime Medical Office Space, Port St. Lucie
    $18 SF/Yr
    21,899 SF

    Prime Medical Office Space, Port St. Lucie

    1,295 SF Available, US-1 Corridor
    10570 Hwy, Port St. Lucie, FL 34952
    View details
    Fountain Business Center: Port St. Lucie Offices
    $25 SF/Yr
    18,382 SF

    Fountain Business Center: Port St. Lucie Offices

    New 3-story office building, flexible suites.
    1380 Import Dr, Port St. Lucie, FL 34953
    View details
    Stadium Business Center Office Space
    $17 SF/Yr
    3,000 SF

    Stadium Business Center Office Space

    Creative Office Suites, Port St. Lucie, FL
    590 Peacock Blvd, Port St. Lucie, FL 34986
    View details
    Fort Pierce Office Space For Lease
    $15 SF/Yr
    4,691 SF

    Fort Pierce Office Space For Lease

    Prime Office Building, 4691 sq ft
    706 7Th St, Fort Pierce, FL 34950
    View details
    Prime Medical Office Space in Frist Blvd.
    $300 /Mo
    2,500 SF

    Prime Medical Office Space in Frist Blvd.

    2500 sq ft Medical Office/Coworking Space
    2401 Frist Blvd, Fort Pierce, FL 34950
    View details

    St Lucie County, FL Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in St Lucie County, FL with 127 listings featured on our commercial real estate exchange. The current inventory includes 80,208,733,870 square feet of properties with an estimated lease value of $3,199,267.

    Estimated lease rates for Office Properties & Spaces in St Lucie County, FL begin at $1.74 SF/Yr, with an average of $39,497 and extend to $2,200,000.
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    Office Properties & Spaces by market

    Browse Office Properties & Spaces for Lease Near St Lucie, FL

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