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    St Lucie County, FL Office Properties & Spaces for Lease

    98 results
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    Ocean View Office Suite
    $1,200 / Mo
    4,500 SF

    Ocean View Office Suite

    221 S Ocean Dr, Fort Pierce, FL 34949

    Second-floor office suite with ocean views available for lease.

    • Ocean view office suite
    • Reasonable lease rate for Hutchinson Island location ($1,200/month year 1)
    • New metal roof and impact windows
    • Approximately 1,050 sq ft with entry/conference room + 4 offices + private bathroom
    • Join established businesses (Coldwell Banker, Ryen Marine Insurance Group)
    Updated: Dec 19, 2025
    View details
    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    3801 Oleander Ave, Fort Pierce, FL 34982

    Flexible leasing options in a busy industrial corridor.

    • Modified Gross Lease: Taxes and insurance included in the $17/sq ft rate.
    • Flexible Leasing Options: Multiple 1500 sqft units available for single or multiple space rentals.
    • Move‑in Ready & Versatile: Sleek, modern flex office spaces suitable for a variety of businesses.
    • Private Amenities: Each unit includes a private bathroom, showroom/office space, and warehouse/storage area.
    • Prime Location: Situated on Oleander Avenue, a busy industrial corridor with excellent access to I‑95, US‑1, and the Florida Turnpike.
    Updated: Dec 18, 2025
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    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Flexible leasing options in modern flex office spaces.

    3801 Oleander Ave, Fort Pierce, FL 34982
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    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Modern flex office spaces for lease in Fort Pierce, Florida.

    3801 Oleander Ave, Fort Pierce, FL 34982
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    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Modern flex office spaces for lease on busy industrial corridor.

    3801 Oleander Ave, Fort Pierce, FL 34982
    View details
    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Versatile flex spaces on a busy industrial corridor.

    3801 Oleander Ave, Fort Pierce, FL 34982
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    Medical Co-working Space Available
    $5,416 / Mo
    63,341 SF

    Medical Co-working Space Available

    Co-working space for medical professionals near major hospitals.

    2401 Frist Blvd, Fort Pierce, FL 34950
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    Fort Pierce Office/Warehouse Opportunity
    $2,200,000
    59,677 SF

    Fort Pierce Office/Warehouse Opportunity

    11,476 sq. ft. Class B office building for rent.

    3030 N 25Th St, Fort Pierce, FL 34946
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    Profitable Office Space with Tenants
    $275,000

    Profitable Office Space with Tenants

    Turnkey office property with long-term tenants and immediate cash flow.

    544 NW University Blvd Blvd, Port Saint Lucie, FL 34986
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    Mixed-Use Property Near Turnpike
    $3,300 / Mo
    1,524 SF

    Mixed-Use Property Near Turnpike

    Flexible mixed-use property with residential and commercial potential.

    1892 SW Biltmore St, Port Saint Lucie, FL 34984
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    Professional Office Space Available
    $2,287 / Mo
    998 SF

    Professional Office Space Available

    Class A office suite with private offices and open space.

    2100 SE Hillmoor Dr, Port St Lucie, FL 34952
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    Landmark Office Building in Fort Pierce
    $16 SF/Yr
    56,628 SF

    Landmark Office Building in Fort Pierce

    5,400 SF office space available for lease.

    2222 Colonial Rd, Fort Pierce, FL 34950
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    Fort Pierce Office Space Available
    $16 SF/Yr
    18,228 SF

    Fort Pierce Office Space Available

    2,400 SF office space for lease in Fort Pierce.

    2222 Colonial Rd, Fort Pierce, FL 34950
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    Medical Office Near Lawnwood Hospital
    $500,000

    Medical Office Near Lawnwood Hospital

    Turnkey medical office space in Fort Pierce healthcare corridor.

    1801 S 23Rd St, Fort Pierce, FL 34950
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    Freestanding Building on US Highway
    $26 SF/Yr
    46,609 SF

    Freestanding Building on US Highway

    General Commercial zoning ideal for retail, medical, or restaurant.

    10244 S Us Highway 1, Port St Lucie, FL 34952
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    Medical Office Space For Rent
    $24 SF/Yr
    998 SF

    Medical Office Space For Rent

    Updated medical office space available for rent in Port St. Lucie.

    1801 SE Hillmoor Dr, Port St Lucie, FL 34952
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    Port St. Lucie Executive Office
    $1,527 / Mo
    998 SF

    Port St. Lucie Executive Office

    Executive office suite in Port St. Lucie medical corridor.

    2100 SE Hillmoor Dr, Port St Lucie, FL 34952
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    Fort Pierce Office/Warehouse Space
    $10,000 / Mo
    4,648 SF

    Fort Pierce Office/Warehouse Space

    Versatile commercial property on US 1 with high visibility.

    3535 Old Dixie Hwy, Fort Pierce, FL 34946
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    Prime Medical Office Space, Port St. Lucie
    $18 SF/Yr
    21,899 SF

    Prime Medical Office Space, Port St. Lucie

    1,295 SF Available, US-1 Corridor

    10570 Us Highway 1, Port St. Lucie, FL 34952
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    Fountain Business Center: Port St. Lucie Offices
    $25 SF/Yr
    18,382 SF

    Fountain Business Center: Port St. Lucie Offices

    New 3-story office building, flexible suites.

    1380 Import Dr, Port St. Lucie, FL 34953
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    Stadium Business Center Office Space
    $17 SF/Yr
    3,000 SF

    Stadium Business Center Office Space

    Creative Office Suites, Port St. Lucie, FL

    590 Peacock Blvd, Port St. Lucie, FL 34986
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    Fort Pierce Office Space For Lease
    $15 SF/Yr
    4,691 SF

    Fort Pierce Office Space For Lease

    Prime Office Building, 4691 sq ft

    706 7Th St, Fort Pierce, FL 34950
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    Prime Medical Office Space in Frist Blvd.
    $300 / Mo
    2,500 SF

    Prime Medical Office Space in Frist Blvd.

    2500 sq ft Medical Office/Coworking Space

    2401 Frist Blvd, Fort Pierce, FL 34950
    View details
    Becker Town Center: Prime FL Space
    Contact for pricing
    80,000 SF

    Becker Town Center: Prime FL Space

    80,000 SF Retail/Office Opportunity

    0 Port St Lucie Blvd, Port St. Lucie, FL 34953
    View details

    St Lucie County, FL Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in St Lucie County, FL with 122 listings featured on our commercial real estate exchange. The current inventory includes 58,680,998,866 square feet of properties with an estimated lease value of $1,827 /Mo.

    Estimated lease rates for Office Properties & Spaces in St Lucie County, FL begin at $3 SF/Yr, with an average of $23 SF/Yr and extend to $140 SF/Yr.
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    Office Properties & Spaces by market

    Browse Office Properties & Spaces for Lease Near St Lucie, FL

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