Advertise
    Port Saint Lucie, FL
    Office

    Port Saint Lucie, FL Office Spaces for Lease

    Notify Me
    List
    Map
    Fort Pierce, FL Jensen Beach, FL Stuart, FL Vero Beach, FL Palm City, FL Hobe Sound, FL Indiantown, FL
    14 properties
    Sort:
    Flexible Office Suite with Private Office
    Updated: Jul 16
    Flexible Office Suite with Private Office

    250-270 NW Peacock Blvd, Port Saint Lucie, FL 34986

    $3,500/Mo
    1,300 sqft
    1,300 +/- SF commercial suite (Suite 104) at 270 NW Peacock Boulevard in St. Lucie West
    Flexible layout with an open floor plan plus 1 private office and 1 restroom
    Zoned CG (General Commercial) for professional offices, medical/wellness, retail, boutique fitness, and service uses
    Convenient access to Interstate 95 and Florida's Turnpike
    Just 2 minutes from Clover Park (New York Mets spring training home)
    View details
    Well-Maintained Property For Sale
    Updated: Nov 24, 2025
    Well-Maintained Property For Sale

    7430-7448 S Federal Hwy, Port Saint Lucie, FL

    $2,550/Mo
    13,129 sqft
    Great short term upside potential
    Great street visibility
    Easy access
    Well maintained property
    Long term occupants
    View details
    Port St. Lucie Office Space
    Port St. Lucie Office Space

    155 SW Port St Lucie Blvd, Port Saint Lucie, FL

    $27 SF/Yr
    2,500 sqft

    2,500 SF office space in a thriving commercial corridor.

    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Flex Warehouse Suite with Offices
    Flex Warehouse Suite with Offices

    1746-1746 Sw Biltmore St, Port Saint Lucie, FL 34984

    $1,800/Mo

    Includes two offices, one restroom, and primarily warehouse space—suited to light distribution and back-office operations.

    View details
    Climate-Controlled Distribution Headquarters
    Climate-Controlled Distribution Headquarters

    760 NW Enterprise Dr, Port Saint Lucie, FL 34986

    Contact for pricing
    122,626 sqft

    18–36' clear heights, 15 dock-high doors, and premium office build-outs on an 8.3-acre campus.

    View details
    Port St. Lucie Office Space
    Port St. Lucie Office Space

    7664 S US Hwy 1, Port Saint Lucie, FL

    $18 SF/Yr
    3,753 sqft

    Versatile office space in a high-traffic Port St. Lucie location.

    View details
    Medical Office Space For Rent
    Medical Office Space For Rent

    1631 SW Gatlin Blvd, Port Saint Lucie, FL

    $25 SF/Yr
    1,288 sqft

    Medical office space in Gatlin Kidney Care medical facility.

    View details
    Retail, Office, Medical Space Available
    Retail, Office, Medical Space Available

    1449-1479 SW Gatlin Blvd, Port Saint Lucie, FL

    $44 SF/Yr
    1,184 sqft

    New retail, office, and medical space for rent.

    View details
    Port Saint Lucie Office Space
    Port Saint Lucie Office Space

    900 E Prima Vista Blvd, Port Saint Lucie, FL

    $13 SF/Yr
    13,029 sqft

    Office space available for lease in Port Saint Lucie, FL.

    View details
    Furnished Office Space Available
    Furnished Office Space Available

    526 SW Port St Lucie Blvd, Port Saint Lucie, FL

    $15 SF/Yr
    5,111 sqft

    Professional office space with multiple configurations, fully furnished and equipped.

    View details
    Professional Office Space For Lease
    Professional Office Space For Lease

    550 SE Port St Lucie Blvd, Port Saint Lucie, FL

    $900/Mo
    700 sqft

    Two-story office building with recent renovations and ample parking.

    View details
    Shared Medical Office Space
    Shared Medical Office Space

    10377 S US Hwy 1, Port Saint Lucie, FL

    $3,500/Mo
    1,604 sqft

    Shared medical office space available near hospital and major roadways.

    View details
    Single-Story Office Building For Rent
    Single-Story Office Building For Rent

    120-128 SW Chamber Ct, Port Saint Lucie, FL

    $22 SF/Yr
    4,020 sqft

    Single-story office building with immediate availability and hurricane impact glass.

    View details
    Office Space For Rent
    Office Space For Rent

    1631 NW St Lucie West Blvd, Port Saint Lucie, FL

    $22 SF/Yr
    1,629 sqft

    Office space available for lease in Port Saint Lucie, FL.

    View details
    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 14 Active listings in Port Saint Lucie, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Versatile Commercial Retail Office Unit
    Versatile Commercial Retail Office Unit

    Port St Lucie, FL 34983

    $2,000/Mo
    900 sqft

    Lease a 900 SF commercial unit on SW Bayshore Boulevard with a flexible layout and ample on-site parking.

    View details
    Medical Office Space on Lake
    Medical Office Space on Lake

    Fort Pierce, FL 34986

    $26 SF/Yr
    1,958 sqft

    Single-story medical office with lake views and recent upgrades.

    View details
    Flexible Coworking Office Space
    Flexible Coworking Office Space

    Port St Lucie, FL 34986

    $3,000/Mo

    Turnkey coworking membership with flexible day schedules for professionals and service providers in a commercial corridor setting.

    View details
    Office Space Available For Rent
    Office Space Available For Rent

    Fort Pierce, FL 34986

    Contact for pricing
    2,750 sqft

    Office space available for rent in Port St. Lucie, FL.

    View details

    Similar Spaces for Sale in Port Saint Lucie, FL

    Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

    Leased Office Bays Bundle
    Leased Office Bays Bundle

    1082 SW Bayshore Boulevard, Port Saint Lucie, FL 34983

    Contact for pricing

    Two commercial office bays are sold together and currently leased under a term with renewal options.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Melbourne Land for Ground Lease
    Melbourne Land for Ground Lease

    6365 N. Wickham Road, Melbourne, FL 32940

    $36 SF/Yr

    1.2-acre development site in Viera/Suntree area available for lease.

    View details
    Commercial Land in Sebring, Florida
    Commercial Land in Sebring, Florida

    1701 N US 27 Highway, Sebring, FL 33870

    $8,900/Mo

    1.52 acre commercial land parcel in rapidly developing Sebring.

    View details
    Commercial Land with US-41 Frontage
    Commercial Land with US-41 Frontage

    14500 N CLEVELAND Avenue, North Fort Myers, FL 33903

    $10,416/Mo

    Two adjacent commercial parcels totaling about 1.85 acres along US-41 in North Fort Myers.

    View details
    Vacant Commercial Parcel For Sale
    Vacant Commercial Parcel For Sale

    1508 Nw 1st Ave, Miami, FL 33136

    $2,000/Mo

    Vacant commercial land parcel available for sale.

    View details

    Port Saint Lucie, FL Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Port Saint Lucie, FL with 14 listings featured on our commercial real estate exchange. The current inventory includes 49,247 square feet of properties with an estimated lease value of $262.25 SF/Yr.

    Estimated lease rates for Office Spaces in Port Saint Lucie, FL begin at $2.33 SF/Yr, with an average of $21.85 SF/Yr and extend to $44 SF/Yr.
    List
    Map

    Browse Office Spaces for Lease Near Port Saint Lucie, FL

    Popular Searches in Port Saint Lucie, FL

    Popular Categories

    Most Searched ZIP Codes in Port Saint Lucie, FL

    • 34984

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!