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    Port Saint Lucie, FL
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    Port Saint Lucie, FL Office Spaces for Lease

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    Fort Pierce, FL Jensen Beach, FL Stuart, FL
    13 results
    Renaissance Financial
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    Port St. Lucie Office Space
    $27 SF/Yr
    2,500 SF
    Port St. Lucie Office Space

    155 SW Port St Lucie Blvd, Port Saint Lucie, FL

    2,500 SF office space in a thriving commercial corridor.
    • Prime 2,500 SF space suitable for healthcare, professional services, or administrative offices.
    • Excellent frontage on SW Port St. Lucie Blvd. in a prominent building.
    • Located in a thriving commercial corridor with municipal offices, retail, dining, and professional services.
    • Anchored by Great Smile Dental Group.
    • Interior features multiple office spaces, lobby area, kitchen, and restrooms.
    Updated: Apr 25, 2025
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    Port St. Lucie Office Space
    $18 SF/Yr
    3,753 SF
    Port St. Lucie Office Space

    7664 S US Hwy 1, Port Saint Lucie, FL

    Versatile office space in a high-traffic Port St. Lucie location.
    • High visibility location on US‑1 corridor.
    • Large 3,753 SF versatile office space.
    • Multiple office/exam rooms, reception area, and breakroom.
    • Monument sign facing US‑1 for exceptional exposure.
    • Located near the signalized intersection of Prima Vista Blvd. and US‑1.
    Updated: Apr 25, 2025
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    St Lucie West Professional Offices
    $25 SF/Yr
    3,076 SF
    St Lucie West Professional Offices

    Medical and professional offices in the heart of St Lucie West.

    525 NW Lake Whitney Pl, Port Saint Lucie, FL

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    Medical Office Space For Rent
    $25 SF/Yr
    1,288 SF
    Medical Office Space For Rent

    Medical office space in Gatlin Kidney Care medical facility.

    1631 SW Gatlin Blvd, Port Saint Lucie, FL

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    Port Saint Lucie Office Space
    $13 SF/Yr
    13,029 SF
    Port Saint Lucie Office Space

    Office space available for lease in Port Saint Lucie, FL.

    900 E Prima Vista Blvd, Port Saint Lucie, FL

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    Retail, Office, Medical Space Available
    $44 SF/Yr
    1,184 SF
    Retail, Office, Medical Space Available

    New retail, office, and medical space for rent.

    1449-1479 SW Gatlin Blvd, Port Saint Lucie, FL

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    Office Space For Rent
    $22 SF/Yr
    1,629 SF
    Office Space For Rent

    Office space available for lease in Port Saint Lucie, FL.

    1631 NW St Lucie West Blvd, Port Saint Lucie, FL

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    Furnished Office Space Available
    $15 SF/Yr
    5,111 SF
    Furnished Office Space Available

    Professional office space with multiple configurations, fully furnished and equipped.

    526 SW Port St Lucie Blvd, Port Saint Lucie, FL

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    Shared Medical Office Space
    $3,500/Mo
    1,604 SF
    Shared Medical Office Space

    Shared medical office space available near hospital and major roadways.

    10377 S US Hwy 1, Port Saint Lucie, FL

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    Professional Office Space For Lease
    $900/Mo
    700 SF
    Professional Office Space For Lease

    Two-story office building with recent renovations and ample parking.

    550 SE Port St Lucie Blvd, Port Saint Lucie, FL

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    Port Saint Lucie Office Space
    $22 SF/Yr
    8,500 SF
    Port Saint Lucie Office Space

    Office space available for lease in Port Saint Lucie.

    584 NW University Blvd, Port Saint Lucie, FL

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    Single-Story Office Building For Rent
    $22 SF/Yr
    4,020 SF
    Single-Story Office Building For Rent

    Single-story office building with immediate availability and hurricane impact glass.

    120-128 SW Chamber Ct, Port Saint Lucie, FL

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    Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 13 Active listings in Port Saint Lucie, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Flexible Co-working Space For Rent
    $3,000/Mo
    Flexible Co-working Space For Rent

    Co-working space in St. Lucie West, flexible terms.

    Port St Lucie, FL 34986

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    Flex Industrial Condo Unit
    $1,750/Mo
    Flex Industrial Condo Unit

    Centralized flex unit combines office space, a restroom, and open warehouse area for versatile business operations.

    Port St Lucie, FL 34983

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    Medical Office Space on Lake
    $26 SF/Yr
    1,958 SF
    Medical Office Space on Lake

    Single-story medical office with lake views and recent upgrades.

    Fort Pierce, FL 34986

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    Office Space Available For Rent
    Contact for pricing
    2,750 SF
    Office Space Available For Rent

    Office space available for rent in Port St. Lucie, FL.

    Fort Pierce, FL 34986

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    Similar Spaces for Sale in Port Saint Lucie, FL

    Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

    Well-Maintained Property For Sale
    $1,290,000
    13,129 SF
    Well-Maintained Property For Sale

    Well-maintained property with long-term occupants and upside potential.

    7430-7448 S Federal Hwy, Port Saint Lucie, FL

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Melbourne Land for Ground Lease
    Contact for pricing
    Melbourne Land for Ground Lease

    1.2-acre development site in Viera/Suntree area available for lease.

    6365 N. Wickham Road, Melbourne, FL 32940

    View details
    Downtown Winter Haven Commercial Land
    $29,940 SF/Yr
    Downtown Winter Haven Commercial Land

    City-approved commercial land in a growing business district.

    511 AVENUE G NW, Winter Haven, FL 33881

    View details
    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF
    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792

    View details
    Lakeland Commercial Business Park Spaces
    Contact for pricing
    Lakeland Commercial Business Park Spaces

    Commercial spaces for lease in West Lakeland business park.

    2525 Drane Field Road, Lakeland, FL 33811

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    Port Saint Lucie, FL Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Port Saint Lucie, FL with 13 listings featured on our commercial real estate exchange. The current inventory includes 46,394 square feet of properties with an estimated lease value of $275 SF/Yr.

    Estimated lease rates for Office Spaces in Port Saint Lucie, FL begin at $13 SF/Yr, with an average of $22 SF/Yr and extend to $44 SF/Yr.
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