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    Leesburg, FL Office Properties & Spaces for Lease

    17 results
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    Medical Office Near UF Health
    $26 SF/Yr
    8,642 SF

    Medical Office Near UF Health

    640 S Lake St, Leesburg, FL 34748

    Medical office space for lease near UF Health Leesburg Hospital.

    • Directly across from UF Health Leesburg Hospital in a key medical hub.
    • 4,072 SQFT medical office space zoned C‑2.
    • Features eight exam rooms, multiple private offices, and a dedicated surgery room with private waiting room.
    • Abundant parking with 44+ spaces.
    • Recently replaced roof (3 years ago).
    Updated: Jan 22
    View details
    Leesburg Mixed-Use Office/Warehouse Facility
    $2,400 / Mo
    1,976 SF

    Leesburg Mixed-Use Office/Warehouse Facility

    2848 W Main St, Leesburg, FL 34748

    Office/warehouse with mixed-use potential in Leesburg Commerce Park.

    • Excellent visibility facing W Main Street in Leesburg Commerce Park.
    • Convenient access to Highway 27, I‑75, and the Turnpike.
    • Mixed‑use potential including office, warehouse, and light manufacturing.
    • Warehouse with a 14‑foot roll‑up door.
    • Features two private offices and a conference room.
    Updated: Nov 11, 2025
    View details
    Leesburg Mixed-Use Highway Frontage
    $1,850 / Mo
    5,400 SF

    Leesburg Mixed-Use Highway Frontage

    Updated mixed-use building with high visibility on US Highway 441.

    1539 Us Highway 441, Leesburg, FL 34748
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    Downtown Leesburg Office Suites
    $4,800 / Mo

    Downtown Leesburg Office Suites

    Office suites available in historic downtown Leesburg.

    711 W Main St, Leesburg, FL 34748
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    Medical Office Space Available
    Contact for pricing
    5,396 SF

    Medical Office Space Available

    Move-in ready, renovated medical suites with ample parking.

    600 W North Blvd, Leesburg, FL 34748
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    Downtown Leesburg Office Space Available
    $92,962

    Downtown Leesburg Office Space Available

    Leesburg office space for lease in growing downtown area.

    410 W Main St, Leesburg, FL 34748
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    Medical Professional Building on US Hwy
    $57,600

    Medical Professional Building on US Hwy

    3,600+/- SF medical professional building for lease on US Hwy

    9846 Us Highway 441, Leesburg, FL 34788
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    Turnkey Medical/Professional Office Space
    $24,750

    Turnkey Medical/Professional Office Space

    Turnkey medical/professional office space for lease in Leesburg, Florida.

    33049 Professional Dr, Leesburg, FL 34788
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    Downtown Leesburg Freestanding Office Building
    $28,800

    Downtown Leesburg Freestanding Office Building

    1,600 SF office building in historic downtown Leesburg.

    2017 W Main St, Leesburg, FL 34748
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    Medical Suite Near UF Health
    $21,000

    Medical Suite Near UF Health

    Medical suite for lease directly across from UF Health.

    601 E Dixie Ave, Leesburg, FL 34748
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    Renovated Office Space Available
    Contact for pricing
    2,504 SF

    Renovated Office Space Available

    Office space for rent with recent renovations and ample parking.

    106 W Blvd N, Leesburg, FL
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    Retail/Medical Space on Highway 441
    Contact for pricing
    3,375 SF

    Retail/Medical Space on Highway 441

    Retail or medical spaces available on a high-traffic corridor.

    1450 E Blvd N, Leesburg, FL
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    Turnkey Medical/Professional Office Space
    $24,750

    Turnkey Medical/Professional Office Space

    Turnkey medical/professional office space for lease in Leesburg, Florida.

    33049 Professional Dr, Leesburg, FL 34788
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    Downtown Leesburg Freestanding Office Building
    $23,940

    Downtown Leesburg Freestanding Office Building

    1,600 SF office building in historic downtown Leesburg.

    2017 W Main St, Leesburg, FL 34748
    View details
    Medical Suite Near UF Health
    $21,000

    Medical Suite Near UF Health

    Medical suite for lease directly across from UF Health at Leesburg.

    601 E Dixie Ave, Leesburg, FL 34748
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    Leesburg Medical Office Space for Lease
    Contact for pricing
    35,116 SF

    Leesburg Medical Office Space for Lease

    Prime Medical Office Suites Available in Leesburg, FL

    106 North Blvd, Leesburg, FL 34748
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    First Class Professional Office Space
    $63,600

    First Class Professional Office Space

    State-of-the-art office space with upgrades and ample parking.

    1904 Thomas Ave, Leesburg, FL 34748
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    Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 17 Active listings in Leesburg, FL, we suggest exploring alternatives. Similar 18 Properties for Sales.

    Explore Similar Spaces for Sale in Leesburg, FL

    Consider Similar Space for Sale. We found 18 Spaces in Nearby Locations matching your search parameters.

    Leesburg Commercial Building For Sale
    $339,000
    1,242 SF

    Leesburg Commercial Building For Sale

    Rehabilitated commercial building on high-traffic corridor, adaptable for professional use.

    1821 Us Highway 441, Leesburg, FL 34748
    View details
    Downtown Leesburg Professional Office Building
    $599,000
    2,968 SF

    Downtown Leesburg Professional Office Building

    Well-maintained office building in downtown Leesburg with tenant in place.

    1029 W Magnolia St, Leesburg, FL 34748
    View details
    Leesburg Mixed-Use Commercial Property
    $1,600,000
    15,300 SF

    Leesburg Mixed-Use Commercial Property

    Mixed-use commercial property with medical suites and self-storage units.

    711 N 3Rd St, Leesburg, FL 34748
    View details
    Highway Commercial Mixed-Use Opportunity
    $1,750,000
    1.58 Acres

    Highway Commercial Mixed-Use Opportunity

    Mixed-use property with highway frontage and development potential.

    727 S 14Th St, Leesburg, FL 34748
    View details
    Leesburg Office Building For Sale
    $495,075
    2,829 SF

    Leesburg Office Building For Sale

    Flexible office space in Leesburg, Florida with investment potential.

    32644 Blossom Ln, Leesburg, FL 34788
    View details
    Leesburg Office Building For Sale
    Contact for pricing
    2,573 SF

    Leesburg Office Building For Sale

    2,573 SF office building in high-growth Leesburg area.

    712 S 14Th St, Leesburg, FL 34748
    View details
    Medical Income Property Near UF
    $1,249,000

    Medical Income Property Near UF

    Single tenant medical building in UF Health Medical Plaza.

    700 Doctors Ct, Leesburg, FL 34748
    View details

    Leesburg, FL Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Leesburg, FL with 35 listings featured on our commercial real estate exchange. The current inventory includes 462,520,080 square feet of properties with an estimated lease value of $40 SF/Yr.

    Estimated lease rates for Office Properties & Spaces in Leesburg, FL begin at $14 SF/Yr, with an average of $20 SF/Yr and extend to $26 SF/Yr.
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    Browse Office Properties & Spaces for Lease Near Leesburg, FL

    Popular Searches in Leesburg, FL

    Most Searched ZIP Codes in Leesburg, FL

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    • 34788

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