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    Portsmouth, NH Mixed-use Properties for Sale

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    Historic Portsmouth Mixed-Use Gem
    $3,600,000
    0.11 Acres

    Historic Portsmouth Mixed-Use Gem

    56 Market St, Portsmouth, NH 03801

    Mixed-use property with commercial space and residential apartments in Portsmouth.

    • Prime location in the heart of Portsmouth, NH, offering convenient access to amenities, transportation, and cultural attractions.
    • Versatile mixed‑use property with over 6,000 sqft of commercial space and two apartments, providing diverse income potential.
    • Historic building, formerly the Portsmouth Brewery, offering unique character and appeal.
    • Spacious penthouse apartment with 14 ft ceilings.
    • Massive first floor with soaring ceilings and exposed brick walls.
    Updated: Jan 2
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    Mixed-Use Development Opportunity, Portsmouth
    $6,800,000
    0.20 Acres

    Mixed-Use Development Opportunity, Portsmouth

    266 State St, Portsmouth, NH 03801

    Mixed-use development opportunity in the heart of Portsmouth, New Hampshire.

    • Prime location in the heart of Portsmouth, within walking distance of key attractions.
    • Luxury condominium living in a mixed‑use development.
    • Unique penthouse with city views and outdoor space.
    • Integration of historical character with modern design.
    • First floor retail/commercial space.
    Updated: Jul 18, 2025
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    Waterfront Lot Near Downtown Portsmouth
    $1,000,000
    0.41 Acres

    Waterfront Lot Near Downtown Portsmouth

    Waterfront mixed-use property near downtown Portsmouth, offering versatile development opportunities.

    98 Cornwall St, Portsmouth, NH 03801
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    Historic Mixed-Use Portsmouth Gem
    $2,400,000

    Historic Mixed-Use Portsmouth Gem

    Historic Portsmouth mixed-use property with commercial and residential spaces.

    48 Market St, Portsmouth, NH 03801
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    Portsmouth Mixed-Use Opportunity
    $1,200,000

    Portsmouth Mixed-Use Opportunity

    Mixed-use property in Portsmouth Green, flexible zoning, rapid use-change potential.

    2425 Lafayette Rd, Portsmouth, NH 03801
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    Based on your search, we've compiled 128 Potential Opportunities for your consideration. Besides 5 Active listings in Portsmouth, NH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 119 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Kittery Assemblage: Mixed-Use Potential
    $2,250,000

    Kittery Assemblage: Mixed-Use Potential

    Three adjoining properties in Kittery with redevelopment potential.

    143 State Rd, Kittery, ME 03904
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    Prime Kittery Commercial Site
    $2,500,000
    2.17 Acres

    Prime Kittery Commercial Site

    High-visibility Route 1 location, excellent zoning.

    275 Us Route 1, Kittery, ME 03904
    View details
    Route One Flex Space For Sale
    $370,000
    3,125 SF

    Route One Flex Space For Sale

    York, ME commercial condo: 3,125 sq ft, high traffic location.

    433 Us-1, York, ME 03909
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    Route One York Commercial Condo
    $385,000
    3,125 SF

    Route One York Commercial Condo

    Prime Location, Versatile Space, High Traffic

    433 Rte, York, ME 03909
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    Explore Off-Market Properties in Portsmouth, NH

    Consider similar Off-Market properties in Portsmouth, NH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    112 Penhallow St

    112 Penhallow St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,732 SF
    Value Estimation
    $340,000
    112 Penhallow St, Portsmouth, NH 03801-3833
    View details
    60 Market St

    60 Market St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,359 SF
    Value Estimation
    $310,000
    60 Market St, Portsmouth, NH 03801-3705
    View details
    54 Ct St

    54 Ct St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,998 SF
    Value Estimation
    $1,835,000
    54 Ct St, Portsmouth, NH 03801-4439
    View details
    278 State St

    278 State St

    OFFICE/RESIDENTIAL (MIXED USE) • 6,930 SF
    Value Estimation
    $280,000
    278 State St, Portsmouth, NH 03801-4014
    View details
    101 Market St

    101 Market St

    OFFICE/RESIDENTIAL (MIXED USE) • 6,585 SF
    Value Estimation
    $380,000
    101 Market St, Portsmouth, NH 03801-3703
    View details
    70 Congress St

    70 Congress St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,908 SF
    Value Estimation
    $285,000
    70 Congress St, Portsmouth, NH 03801
    View details
    140 Edmond Ave

    140 Edmond Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 2,422 SF
    Value Estimation
    $845,000
    140 Edmond Ave, Portsmouth, NH 03801-3562
    View details
    180 Islington St

    180 Islington St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,354 SF
    Value Estimation
    $255,000
    180 Islington St, Portsmouth, NH 03801-4204
    View details
    112 State St

    112 State St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,620 SF
    Value Estimation
    $300,000
    112 State St, Portsmouth, NH 03801-3826
    View details
    1000 Woodbury Ave

    1000 Woodbury Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 1.28 Acres
    Value Estimation
    $315,000
    1000 Woodbury Ave, Portsmouth, NH 03801-3216
    View details
    110 State St

    110 State St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,312 SF
    Value Estimation
    $365,000
    110 State St, Portsmouth, NH 03801-1900
    View details
    177 Bartlett St

    177 Bartlett St

    OFFICE/RESIDENTIAL (MIXED USE) • 7,202 SF
    Value Estimation
    $305,000
    177 Bartlett St, Portsmouth, NH 03801-3672
    View details
    181 Hl St

    181 Hl St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.37 Acres
    Value Estimation
    $330,000
    181 Hl St, Portsmouth, NH 03801-3923
    View details
    8 Bow St

    8 Bow St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,101 SF
    Value Estimation
    $370,000
    8 Bow St, Portsmouth, NH 03801-3802
    View details
    92 Pleasant St

    92 Pleasant St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,568 SF
    Value Estimation
    $265,000
    92 Pleasant St, Portsmouth, NH 03801-4505
    View details
    320 Un St

    320 Un St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,070 SF
    Value Estimation
    $325,000
    320 Un St, Portsmouth, NH 03801-5052
    View details
    15 Pickering Ave

    15 Pickering Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 0.44 Acres
    Value Estimation
    $395,000
    15 Pickering Ave, Portsmouth, NH 03801-4629
    View details
    97 Chestnut St

    97 Chestnut St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,920 SF
    Value Estimation
    $310,000
    97 Chestnut St, Portsmouth, NH 03801-4466
    View details
    30 Hancock St

    30 Hancock St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,684 SF
    Value Estimation
    $235,000
    30 Hancock St, Portsmouth, NH 03801
    View details

    Portsmouth, NH Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 124 mixed-use properties for sale in Portsmouth, NH, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 338,460 square feet of properties for sale, with an estimated market value of $34,895,000.

    Prices for multi use buildings in Portsmouth, NH start at $225,000, averaging $1,090,468, and reaching up to $6,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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