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    Barnstable, MA Mixed-use Properties for Sale

    13 results
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    Restaurant Space in Downtown Hyannis
    $499,000
    2,256 SF

    Restaurant Space in Downtown Hyannis

    517 Main St, Hyannis, MA 02601

    Turnkey restaurant with flexible space in the heart of Hyannis.

    • Prime Downtown Main Street location in Hyannis, close to attractions, ferries, the airport, shopping, and entertainment.
    • Licensed restaurant space with 70 indoor seats and 24 outdoor patio seats.
    • Fully equipped commercial kitchen ready for immediate use.
    • Remodeled second floor with flexible space for storage, office, or a one‑bedroom residential unit.
    • Utilities include natural gas heating, wall unit cooling, and public water/sewer.
    Updated: Mar 4
    View details
    Hyannis Commercial Space For Sale
    $2,250,000
    13,242 SF

    Hyannis Commercial Space For Sale

    338 Main St, Hyannis, MA 02601

    Prime commercial space in downtown Hyannis with diverse tenant mix.

    • Prime downtown Hyannis location with high visibility and foot traffic.
    • Significant commercial space: 13,424 sq ft on a prominent corner lot.
    • Diverse and dependable income stream from established tenants (restaurants, jujutsu studio, offices).
    • Private parking lot providing convenience for tenants and visitors.
    • Located in a thriving business district surrounded by shops, restaurants, and entertainment.
    Updated: Dec 1, 2025
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    Main Street Retail and Residence
    Pending
    $675,000
    2,112 SF

    Main Street Retail and Residence

    Prime Hyannis location with retail space and on-site residence.

    547 Main St, Hyannis, MA 02601
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    Downtown Hyannis Mixed-Use Property
    $1,285,000
    4,032 SF

    Downtown Hyannis Mixed-Use Property

    Turnkey mixed-use property with buildable lot in downtown Hyannis.

    574 Main St, Hyannis, MA 02601
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    Turn-Key Investment in Hyannis, MA
    $2,000,000
    3,415 SF

    Turn-Key Investment in Hyannis, MA

    Fully renewed mixed-use property with immediate income potential.

    712 Main St, Hyannis, MA 02601
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    Hyannis Mixed-Use Redevelopment Opportunity
    $2,800,000
    11,790 SF

    Hyannis Mixed-Use Redevelopment Opportunity

    Prime commercial property with redevelopment potential in Hyannis, Massachusetts.

    453 Main St, Hyannis, MA 02601
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    Downtown Hyannis Commercial Space
    $2,250,000
    13,242 SF

    Downtown Hyannis Commercial Space

    Prime commercial space in thriving downtown Hyannis business district.

    338 Main St, Hyannis, MA 02601
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    Commercial-Residential Zoned Multi-Use Property
    Contact for pricing

    Commercial-Residential Zoned Multi-Use Property

    Multi-use property with office and restorable residence in Barnstable.

    1049 Main St, West Barnstable, MA 02668
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    Former Craigville General Store
    Contact for pricing

    Former Craigville General Store

    Mixed-use property near beaches with high visibility and parking.

    628 Craigville Beach Rd, Centerville, MA 02632
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    Mixed-Use Property with Income Potential
    $625,000

    Mixed-Use Property with Income Potential

    Mixed-use property with residential and commercial rental units.

    657 Yarmouth Rd, Hyannis, MA 02601
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    Main Street Mixed-Use Investment
    Contact for pricing
    11,790 SF

    Main Street Mixed-Use Investment

    Prime Hyannis property with restaurant, apartments, and redevelopment potential.

    453 Main St, Hyannis, MA 02601
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    Historic Hyannis Mixed-Use Property
    $1,350,000
    3,280 SF

    Historic Hyannis Mixed-Use Property

    Charming 1853 building, investment opportunity.

    35 Pleasant St, Barnstable, MA 02601
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    Prime Barnstable Mixed-Use Property
    $1,950,000
    11,740 SF

    Prime Barnstable Mixed-Use Property

    11,740 SF, 3.18 Acres, 40 Parking Spaces

    749 Main St, Barnstable, MA 02601
    View details
    Based on your search, we've compiled 181 Potential Opportunities for your consideration. Besides 13 Active listings in Barnstable, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 164 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Mixed-Use Acre on Main Street
    Pending
    $886,000
    4,440 SF

    Mixed-Use Acre on Main Street

    Adaptable mixed-use property with residential and commercial potential on Main Street.

    467 Main St, West Dennis, MA 02670
    View details
    West Dennis Mixed-Use Retail Opportunity
    Pending
    $886,000
    4,440 SF

    West Dennis Mixed-Use Retail Opportunity

    Retail space with residential units in West Dennis, Massachusetts.

    467 Main St, West Dennis, MA 02670
    View details
    Historic Cape Cod Mixed-Use Property
    Contact for pricing
    3,021 SF

    Historic Cape Cod Mixed-Use Property

    Charming 1880 mixed-use property with antique shop and residence.

    1424 Main St, Brewster, MA 02631
    View details
    Commercially Zoned Ranch with Residence
    $675,000
    1,204 SF

    Commercially Zoned Ranch with Residence

    Unique opportunity: live and work or convert to full office.

    195 Underpass Rd, Brewster, MA 02631
    View details

    Explore Off-Market Properties in Barnstable, MA

    Consider similar Off-Market properties in Barnstable, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    749 Main St

    749 Main St

    Individual retail properties • 11,740 SF
    Value Estimation by Request
    749 Main St, Barnstable, MA 02601
    View details
    223 Pne St

    223 Pne St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.72 Acres
    Value Estimation by Request
    223 Pne St, Centerville, MA 02632-3224
    View details
    465 Falmouth Rd

    465 Falmouth Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 2.74 Acres
    Value Estimation by Request
    465 Falmouth Rd, Hyannis, MA 02601-2596
    View details
    891 Main St

    891 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.23 Acres
    Value Estimation by Request
    891 Main St, Osterville, MA 02655-2059
    View details
    3206 Main St

    3206 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,440 SF
    Value Estimation
    $530,000
    3206 Main St, Barnstable, MA 02630-1107
    View details
    209 Main St

    209 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 14,540 SF
    Value Estimation
    $2,835,000
    209 Main St, Hyannis, MA 02601-4048
    View details
    1645 Santuit Newtown Rd

    1645 Santuit Newtown Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 1,680 SF
    Value Estimation by Request
    1645 Santuit Newtown Rd, Cotuit, MA 02635-2512
    View details
    135 Cotuit Rd

    135 Cotuit Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 7,804 SF
    Value Estimation
    $1,915,000
    135 Cotuit Rd, Marstons Mills, MA 02648-1839
    View details
    707 Main St

    707 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.53 Acres
    Value Estimation by Request
    707 Main St, Osterville, MA 02655-1954
    View details
    1085 Main St

    1085 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 1.01 Acres
    Value Estimation
    $900,000
    1085 Main St, West Barnstable, MA 02668-1152
    View details
    3280 Main St

    3280 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 2.18 Acres
    Value Estimation by Request
    3280 Main St, Barnstable, MA 02630
    View details

    Barnstable, MA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 177 mixed-use properties for sale in Barnstable, MA, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 1,498,900 square feet of properties for sale, with an estimated market value of $66,979,000.

    Sale prices for multi use buildings in Barnstable, MA start at $60,000, averaging $752,573, and reaching up to $10,385,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Mixed-use properties for Sale Near Barnstable, MA

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    Most Searched ZIP Codes in Barnstable, MA

    • 02601
    • 02632
    • 02668
    • 02655
    • 02635
    • 02630
    • 02648

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