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    Barnstable, MA Mixed-use Properties for Sale

    6 results
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    Restaurant Space in Downtown Hyannis
    $499,000
    2,256 SF

    Restaurant Space in Downtown Hyannis

    517 Main Street, Hyannis, MA 02601

    Turnkey restaurant with flexible space in the heart of Hyannis.

    • Prime Downtown Main Street location in Hyannis, close to attractions, ferries, the airport, shopping, and entertainment.
    • Licensed restaurant space with 70 indoor seats and 24 outdoor patio seats.
    • Fully equipped commercial kitchen ready for immediate use.
    • Remodeled second floor with flexible space for storage, office, or a one‑bedroom residential unit.
    • Utilities include natural gas heating, wall unit cooling, and public water/sewer.
    Updated: Feb 23
    View details
    Hyannis Commercial Space For Sale
    $2,195,000
    13,242 SF

    Hyannis Commercial Space For Sale

    338 Main Street, Hyannis, MA 02601

    13,424 SF commercial space in downtown Hyannis.

    • Prime downtown Hyannis location on a prominent corner lot.
    • 13,424 sq ft of commercial space.
    • Diverse and dependable income stream from a mix of tenants.
    • Private parking lot for tenants and visitors.
    • High visibility and steady foot traffic in a thriving business district.
    Updated: Dec 1, 2025
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    Turn-Key Investment in Hyannis, MA
    $2,000,000
    3,415 SF

    Turn-Key Investment in Hyannis, MA

    Fully renewed mixed-use property with immediate income potential.

    712 Main Street, Hyannis, MA 02601
    View details
    Downtown Hyannis Mixed-Use Property
    $1,285,000
    4,032 SF

    Downtown Hyannis Mixed-Use Property

    Turnkey mixed-use property with buildable lot in downtown Hyannis.

    574 Main Street, Hyannis, MA 02601
    View details
    Downtown Hyannis Commercial Space
    $2,195,000
    13,242 SF

    Downtown Hyannis Commercial Space

    Prime commercial space in thriving downtown Hyannis business district.

    338 Main, Hyannis, MA 2601
    View details
    Hyannis Mixed-Use Investment Opportunity
    $379,000
    1,380 SF

    Hyannis Mixed-Use Investment Opportunity

    Commercial/Residential building in Hyannis with established business and rental income.

    705 Main St, Barnstable, MA 2601
    View details
    Based on your search, we've compiled 178 Potential Opportunities for your consideration. Besides 6 Active listings in Barnstable, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 164 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    West Dennis Mixed-Use Retail Opportunity
    $886,000
    4,440 SF

    West Dennis Mixed-Use Retail Opportunity

    Retail space with residential units in West Dennis, Massachusetts.

    467 Main Street, West Dennis, MA 02670
    View details
    Mixed-Use Acre on Main Street
    $886,000
    4,440 SF

    Mixed-Use Acre on Main Street

    Adaptable mixed-use property with residential and commercial potential on Main Street.

    467 Main Street, West Dennis, MA 02670
    View details
    Commercially Zoned Ranch with Residence
    $675,000
    1,204 SF

    Commercially Zoned Ranch with Residence

    Unique opportunity: live and work or convert to full office.

    195 Underpass, Brewster, MA 2631
    View details
    Historic Cape Cod Mixed-Use Property
    $799,000
    3,021 SF

    Historic Cape Cod Mixed-Use Property

    Charming 1880 mixed-use property with antique shop and residence.

    1424 Main St, Brewster, MA 2631
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    West Barnstable Mixed-Use Land Parcel
    $250,000
    0.84 Acres

    West Barnstable Mixed-Use Land Parcel

    Versatile 0.84-acre lot suitable for residential or commercial development.

    27 White Cap Lane, West Barnstable, MA 02668
    View details
    Commercial Land on Iyannough Road
    $1,250,000

    Commercial Land on Iyannough Road

    Commercial land package deal in Qualified Opportunity Zone.

    599 Iyannough Rd, Barnstable, MA 2601
    View details
    Versatile Land Parcel, West Yarmouth
    $239,000
    0.69 Acres

    Versatile Land Parcel, West Yarmouth

    0.69 acre parcel suitable for residential or commercial use.

    Kens Way, West Yarmouth, MA 02673
    View details
    1.46-Acre Vacant Commercial Parcel
    $359,000

    1.46-Acre Vacant Commercial Parcel

    1.46-acre vacant parcel zoned General Commercial II.

    303 Main Street, Dennis, MA 2639
    View details

    Explore Off-Market Properties in Barnstable, MA

    Consider similar Off-Market properties in Barnstable, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    231 Sea St

    231 Sea St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,198 SF
    Value Estimation
    $580,000
    231 Sea St, Hyannis, MA 02601-4573
    View details
    255 Main St

    255 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 11,627 SF
    Value Estimation
    $3,835,000
    255 Main St, Hyannis, MA 02601-4067
    View details
    356 Ss St

    356 Ss St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.27 Acres
    Value Estimation
    $590,000
    356 Ss St, Hyannis, MA 02601-5404
    View details
    4632 Falmouth Rd

    4632 Falmouth Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 4,999 SF
    Value Estimation
    $730,000
    4632 Falmouth Rd, Cotuit, MA 02635-2533
    View details
    17 School St

    17 School St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,168 SF
    Value Estimation by Request
    17 School St, Hyannis, MA 02601-3117
    View details
    606 Main St

    606 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.29 Acres
    Value Estimation
    $2,000,000
    606 Main St, Hyannis, MA 02601-5432
    View details
    45 Main St

    45 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,383 SF
    Value Estimation by Request
    45 Main St, Cotuit, MA 02635-2516
    View details
    1000 Main St

    1000 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 10,970 SF
    Value Estimation
    $1,515,000
    1000 Main St, Centerville, MA 02632-3073
    View details
    1085 Main St

    1085 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 1.01 Acres
    Value Estimation
    $900,000
    1085 Main St, West Barnstable, MA 02668-1152
    View details
    648 Craigville Bch Rd

    648 Craigville Bch Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 3,664 SF
    Value Estimation
    $580,000
    648 Craigville Bch Rd, Centerville, MA 02632-3717
    View details
    645 Main St

    645 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.14 Acres
    Value Estimation
    $545,000
    645 Main St, Hyannis, MA 02601-5458
    View details
    1481 Iyannough Rd

    1481 Iyannough Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 6,666 SF
    Value Estimation
    $1,325,000
    1481 Iyannough Rd, Hyannis, MA 02601-1872
    View details
    675 Main St

    675 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,837 SF
    Value Estimation by Request
    675 Main St, Hyannis, MA 02601-5465
    View details
    605 Main St

    605 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 0.16 Acres
    Value Estimation
    $740,000
    605 Main St, Hyannis, MA 02601-5463
    View details
    517 Main St

    517 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,256 SF
    Value Estimation by Request
    517 Main St, Hyannis, MA 02601-5407
    View details
    211 Cotuit Rd

    211 Cotuit Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 3,408 SF
    Value Estimation
    $785,000
    211 Cotuit Rd, Marstons Mills, MA 02648-5711
    View details
    246 Nn St

    246 Nn St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,200 SF
    Value Estimation
    $700,000
    246 Nn St, Hyannis, MA 02601-3850
    View details
    123 Old Yarmouth Rd

    123 Old Yarmouth Rd

    OFFICE/RESIDENTIAL (MIXED USE) • 736 SF
    Value Estimation by Request
    123 Old Yarmouth Rd, Hyannis, MA 02601-2013
    View details

    Barnstable, MA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 170 mixed-use properties for sale in Barnstable, MA, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 1,470,586 square feet of properties for sale, with an estimated market value of $62,099,000.

    Sale prices for multi use buildings in Barnstable, MA start at $60,000, averaging $722,081, and reaching up to $10,385,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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