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    Barnstable, MA Commercial Real Estate for Sale

    67 results
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    Historic Hyannis Main Street Opportunity
    $574,900
    2,228 SF

    Historic Hyannis Main Street Opportunity

    615 Main St, Hyannis, MA 02601

    Prime commercial space for sale or lease in Hyannis.

    • Prime location on historic Main Street in Hyannis, Cape Cod, with high car and foot traffic.
    • Versatile 2,200 sq ft space suitable for restaurant, retail, or office use.
    • Located in the Hyannis Main Street Business Improvement District (BID), promoting a clean, safe, and economically developed environment.
    • Walking distance to Nantucket Sound beaches and the Melody Tent.
    • Close proximity to Main Street attractions, Cape Cod Hospital, and ferry service to the islands.
    Updated: Feb 25
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    Retro Arcade Bar For Sale
    Pending
    $749,000
    3,092 SF

    Retro Arcade Bar For Sale

    294 Main St, Hyannis, MA 02601

    Unique 99-seat restaurant/bar in Hyannis Main Street Business District.

    • Prime location in the heart of Hyannis Main Street Business Improvement District.
    • Sale includes land, building, improvements, equipment, and decor.
    • 99‑seat restaurant/bar with indoor and outdoor seating.
    • Easy conversion to a different restaurant concept.
    • Close proximity to Main Street attractions, Cape Cod Hospital, island ferry, and Barnstable Airport.
    Updated: Feb 11
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    Hyannis Retail Property For Sale
    $599,000
    2,822 SF

    Hyannis Retail Property For Sale

    Retail property in Hyannis, MA, with redevelopment potential.

    181 Spring St, Hyannis, MA 02601
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    Hyannis Office Building Investment
    $775,000
    2,766 SF

    Hyannis Office Building Investment

    Fully leased office building in Hyannis with stable income.

    243 South St, Hyannis, MA 02601
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    Hyannis Commercial Business Bay/Office Unit
    $330,000
    1,414 SF

    Hyannis Commercial Business Bay/Office Unit

    Commercial business bay/office unit for sale in Hyannis, MA.

    270 Communication Way, Hyannis, MA 02601
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    Prime Corner Commercial Condo, Hyannis
    $899,000
    4,259 SF

    Prime Corner Commercial Condo, Hyannis

    High-visibility 4,200 SF commercial condo in downtown Hyannis.

    615 Main St, Hyannis, MA 02601
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    Reimagined Restaurant in Historic Hyannis
    $2,195,000
    5,504 SF

    Reimagined Restaurant in Historic Hyannis

    Premiere restaurant with modern updates in the heart of Hyannis.

    488 South St, Hyannis, MA 02601
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    Downtown Hyannis Two-Unit Building
    Pending
    $1,399,000
    5,348 SF

    Downtown Hyannis Two-Unit Building

    Two-unit building in downtown Hyannis with investment opportunity.

    328 Main St, Hyannis, MA 02601
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    Hyannis Commercial Condo For Sale
    $795,000
    5,790 SF

    Hyannis Commercial Condo For Sale

    Modern, renovated condo unit in Hyannis business district.

    68 Ctr St Unit, Hyannis, MA 02601
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    Osterville Commercial Property with Dunkin'
    $5,900,000
    19,304 SF

    Osterville Commercial Property with Dunkin'

    Prime commercial property in Osterville, MA with established tenants.

    804 Main St, Osterville, MA 02655
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    Main Street Retail and Residence
    Pending
    $675,000
    2,112 SF

    Main Street Retail and Residence

    Prime Hyannis location with retail space and on-site residence.

    547 Main St, Hyannis, MA 02601
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    Downtown Hyannis Mixed-Use Property
    $1,285,000
    4,032 SF

    Downtown Hyannis Mixed-Use Property

    Turnkey mixed-use property with buildable lot in downtown Hyannis.

    574 Main St, Hyannis, MA 02601
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    Turn-Key Investment in Hyannis, MA
    $2,000,000
    3,415 SF

    Turn-Key Investment in Hyannis, MA

    Fully renewed mixed-use property with immediate income potential.

    712 Main St, Hyannis, MA 02601
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    Historic Hyannis Main Street Property
    $574,900
    2,228 SF

    Historic Hyannis Main Street Property

    Prime location suitable for retail, restaurant, or office use.

    615-617 Main St, Hyannis, MA 02668
    View details
    Hyannis Office Building For Sale
    $826,000

    Hyannis Office Building For Sale

    Fully occupied office building in Hyannis with 7.5% cap rate.

    243 South St, Hyannis, MA 02601
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    Established Uniform Supply Business For Sale
    $849,000

    Established Uniform Supply Business For Sale

    Profitable uniform and equipment supplier serving first responders for 35+ years.

    11 Enterprise Rd, Hyannis, MA 02601
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    Single Car Garage in Osterville
    $85,000
    120 SF

    Single Car Garage in Osterville

    One-story garage in Osterville Village for personal storage.

    920A Main St, Osterville, MA 02655
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    Downtown Hyannis Redevelopment Opportunity
    $745,000

    Downtown Hyannis Redevelopment Opportunity

    Prime redevelopment land in Hyannis' commercial hub.

    43 Pleasant St, Hyannis, MA 02601
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    Versatile Industrial Condo with Mezzanine
    $525,000

    Versatile Industrial Condo with Mezzanine

    1,932 SF industrial condo with mezzanine and customization potential.

    381 Old Falmouth Rd, Marstons Mills, MA 02648
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    Prime Retail Space on Main
    Contact for pricing

    Prime Retail Space on Main

    3,300 SF retail space in downtown Hyannis with parking.

    426 Main St, Hyannis, MA 02601
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    Commercial Condominium in Hyannis
    $545,000
    2,790 SF

    Commercial Condominium in Hyannis

    Commercial condominium for sale or lease in Hyannis, Massachusetts.

    68 Center St, Hyannis, MA 02601
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    Barnstable Land with Development Potential
    $1,150,000
    6.24 Acres

    Barnstable Land with Development Potential

    Vacant land parcel suitable for residential or business ventures.

    Ln Phinney's, Barnstable, MA 02630
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    Commercial-Residential Zoned Multi-Use Property
    Contact for pricing

    Commercial-Residential Zoned Multi-Use Property

    Multi-use property with office and restorable residence in Barnstable.

    1049 Main St, West Barnstable, MA 02668
    View details
    Historic Hyannis Main Street Property
    Contact for pricing

    Historic Hyannis Main Street Property

    2,200 SF space ideal for restaurant or retail.

    615 Main St, Hyannis, MA 02601
    View details

    Barnstable, MA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 48 commercial real estate for sale in Barnstable, MA, showcased through 67 active listings on our real estate platform. These investment opportunities span a total of 1,611,284 square feet of properties for sale, with an estimated market value of $34,782,900.

    Sale prices for business properties in Barnstable, MA start at $85,000, averaging $1,739,145, and reaching up to $5,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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