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Lexington County, SC Medical Office Space for Sale

40 results
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Lexington Commercial Land For Sale
$2,750,000
5.89 Acres

Lexington Commercial Land For Sale

206 BO TIRE Way, Lexington, SC 29072

Pad-ready commercial parcel in high-traffic area, Lexington, SC.

  • Pad‑ready ±5.88‑acre commercial parcel in Publix‑anchored Hendrix Crossing Shopping Center.
  • Located on high‑traffic Hwy 378 corridor with direct access via Bo Tire Way.
  • Fully graded with stormwater infrastructure and all major utilities in place.
  • Zoned Intensive Development (ID) allowing diverse commercial uses.
  • Subdivision potential available.
Updated: Jan 2
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Professional Office Building in Lexington
$229,000
1,596 SF

Professional Office Building in Lexington

1608 W Main Street Apt, suite, flo, Lexington, SC 29072

Commercial office building with multiple private offices in Lexington, SC.

  • Price Reduced to $229,900
  • Located in a highly sought‑after area with fast growth
  • Functional floor plan allows for single or multi‑tenant use
  • Features multiple private offices, reception area, conference room, and break space
  • Easy access to major highways and surrounding amenities
Updated: Oct 30, 2025
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Leesville Commercial Land Opportunity
$275,000
1.96 Acres

Leesville Commercial Land Opportunity

1.96 acres suitable for retail, medical, or office development.

0 E Church Street, Leesville, SC 29070
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Medical Office Building For Sale
$695,000
4,900 SF

Medical Office Building For Sale

4,900 SF medical office building with significant plumbing infrastructure.

110 Atrium Way, Columbia, SC 29223
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West Columbia Medical/Office Park
$7,350,000
39,722 SF

West Columbia Medical/Office Park

Four Class A buildings, 100% occupied, located on Sunset Boulevard.

3221, 3223, 3225, & 3231 Sunset Blvd., West Columbia, SC 29169
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Freestanding Medical Office Investment
$1,250,000
3,200 SF

Freestanding Medical Office Investment

Freestanding medical office building for sale in Northeast Columbia.

131 Wildewood Park Drive, Columbia, SC 29223
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High-Visibility Business/Office Center For Sale
$2,250,000
15,593 SF

High-Visibility Business/Office Center For Sale

Office/retail building with high visibility and customer parking.

7358 Garners Ferry, Columbia, SC 29209
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West Columbia Office/Medical Building
$2,145,000
12,956 SF

West Columbia Office/Medical Building

12,956 SF office/medical building for sale or lease.

3225 Sunset Blvd., West Columbia, SC 29169
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Downtown Office Condos For Sale
$975,000
5,528 SF

Downtown Office Condos For Sale

Four office condos totaling 5,528 SF in downtown Columbia.

2757 Laurel St, Columbia, SC
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Columbia Investment Property For Sale
$1,798,000
6,104 SF

Columbia Investment Property For Sale

Investment opportunity with a publicly traded tenant in Columbia, SC.

1840 Pineview Dr, Columbia, SC
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Medical NNN Investment Opportunity
$2,190,000
4,715 SF

Medical NNN Investment Opportunity

Single tenant medical property for sale in Lexington, SC.

125 Park Pl Ct, Lexington, SC 29072
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Freestanding Office Building For Sale
Contact for pricing
4,200 SF

Freestanding Office Building For Sale

4,200 SF office building for sale or lease.

2901 Millwood Ave., Columbia, SC 29205
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Downtown Columbia Office Building For Sale
$3,000,000
45,500 SF

Downtown Columbia Office Building For Sale

25,000 SF office building in downtown Columbia.

950 Taylor St, Columbia, SC 29201
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Downtown Chapin Commercial Space Available
$400,000
1,410 SF

Downtown Chapin Commercial Space Available

Commercial space suitable for various businesses in downtown Chapin, SC.

104 East Boundary Street, Chapin, SC 29036
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Medical/Office Building Near Lexington Medical
$1,145,000
6,300 SF

Medical/Office Building Near Lexington Medical

6,300 SF building suitable for medical or traditional office use.

101 Medical Cir, West Columbia, SC
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Medical Office Building For Sale
$1,850,000
14,442 SF

Medical Office Building For Sale

Medical office building with ample parking near medical campuses.

1701 Saint Julian Pl, Columbia, SC
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Versatile Commercial Property Near Columbia
$399,000
136,778 SF

Versatile Commercial Property Near Columbia

3.16 acres with 3,000+ sqft building, multiple operational possibilities.

1510 Canal Dr, Columbia, SC 29210
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Office/Medical Building Near Interchange
$262,350
2,915 SF

Office/Medical Building Near Interchange

2,915 SF office/medical building with ample parking for sale.

392 St. Andrews Road, Columbia, SC 29210
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Medical/Office Space in Forest Acres
$1,850,000
14,442 SF

Medical/Office Space in Forest Acres

Medical/office space available for sale or lease in Columbia.

1701 St. Julian Place, Columbia, SC 29204
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Turn-Key Medical Office in Columbia
$3,150,000
9,875 SF

Turn-Key Medical Office in Columbia

Class A medical office in NE Columbia with flexible layout.

229 Longtown Rd, Columbia, SC
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West Columbia Office/Medical Building
$2,145,000
12,956 SF

West Columbia Office/Medical Building

12,956 SF office/medical building in high-demand corridor.

3221-3231 Sunset Blvd, West Columbia, SC
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Columbia Office/Medical Building For Sale
$3,000,000
25,000 SF

Columbia Office/Medical Building For Sale

Office or medical building with flexible floorplates in Columbia.

1527 Park St, Columbia, SC
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West Columbia Medical Office Opportunity
$4,000,000
10,840 SF

West Columbia Medical Office Opportunity

Medical office building for sale in West Columbia, SC.

110 Medical Cir, West Columbia, SC 29169
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Medical Office Condo Near Prisma
$1,980,000
22,263 SF

Medical Office Condo Near Prisma

Class A medical office condo for sale or lease.

2113 Adams Grove Rd., Columbia, SC 29203
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Lexington County, SC Medical Office Space Investment Opportunities Market Analysis

Explore 40 medical office space for sale in Lexington County, SC, showcased through 40 active listings on our real estate platform. These investment opportunities span a total of 10,063,845 square feet of properties for sale, with an estimated market value of $104,189,000.

Sale prices for medical spaces in Lexington County, SC start at $55,000, averaging $1,132,489, and reaching up to $9,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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