Medical Premises

Hidalgo County, TX Medical Office Space for Sale

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Commercial Strip Building with Vacant Expansion Land
Updated: Apr 7
Commercial Strip Building with Vacant Expansion Land

1312 Expressway 83, Penitas, TX 78576

$1,100,000
6,820 sqft 1.76 AC lot
Approximately 6,820 SF commercial strip building
Brick construction with flat and tile roof
About 1.76 acres with ample vacant land for expansion or subdivision
Immediate access from East‑Bound Expressway 83 and Buenavista Street
Recent use: medical clinic, pharmacy/retail, and office/insurance
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1312 Expressway 83, Penitas, TX 78576

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Corner Office Building with Stoplight
Updated: Jun 17
Corner Office Building with Stoplight

301 N Cage Boulevard, Pharr, TX 78577

$1,200,000
8,674 sqft 0.22 AC lot
Corner lot with a stoplight for visibility and signage potential
Approximately 8,674 SF office building on a 0.2238‑acre lot
Near the expressway cross‑exchange connecting McAllen and Edinburg
Accessible approach with ramp
Electric heating with heat pump and central system; central air cooling
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Medical Office with Anesthesia License
Medical Office with Anesthesia License

2401 Cornerstone Boulevard, Edinburg, TX 78539

$795,000
4,644 sqft 0.11 AC lot

Medical office suite with a State-issued Level 2 anesthesia license, porcelain tile finishes, and utilities included with high-speed internet access.

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Medical Office Space with Reception Lobby
Medical Office Space with Reception Lobby

1022 E Griffin Parkway, Mission, TX 78572

$600,000
2,400 sqft 0.17 AC lot

Medical office building with reception area, examination rooms, and central heating and cooling on a small Mission lot.

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Two Single-Story Office Buildings
Two Single-Story Office Buildings

1102 S Airport Dr, Weslaco, TX 78596

$2,200,000
11,556 sqft 1.04 AC lot

Income-producing office property with two single-story buildings occupied by two tenants and B-1 zoning.

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Medical Office Plaza
Medical Office Plaza

1125 James Street, Weslaco, TX 78596

$2,389,000
19,200 sqft 1.75 AC lot

Partially leased medical-oriented property with central HVAC and ramp access.

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Office Condominium Suites
Office Condominium Suites

505 Angelita Drive, Weslaco, TX 78596

$1,070,000
9,114 sqft 0.22 AC lot

Professionally designed office condominium suites with central electric HVAC and on-site parking in Weslaco

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Retail Property with Vacant Space
Retail Property with Vacant Space

1000 N Cage Boulevard, Pharr, TX 78577

$1,250,000
6,264 sqft 0.52 AC lot

B-zoned retail property offers vacant space for lease, central HVAC, and direct access to I-2 and Expressway 83.

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Multi-Office Care and Education Facility
Multi-Office Care and Education Facility

1110 S Airport Drive, Weslaco, TX 78596

$2,199,000
17,375 sqft

Flexible room and office layout with waiting and reception areas, multiple restrooms, and outdoor space with paved parking.

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Medical Office Space with Exam Rooms
Medical Office Space with Exam Rooms

2711,2715,2719, 2723 W Trenton Road, Edinburg, TX 78539

$2,220,000
12,000 sqft

Medical office space with fully equipped exam rooms, reception and waiting area, and accessible ramp approach.

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Executive Office Suites
Executive Office Suites

4836 S Jackson Road, Edinburg, TX 78539

$650,000
3,000 sqft

Executive office property with nine private suites, lobby and reception, conference room, and covered assigned parking.

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Medical Office Building with Parking
Medical Office Building with Parking

844 E US Highway 83, La Joya, TX 78560

$299,998
2,912 sqft 0.18 AC lot

2,912 SF office building previously used as a school with flexible room layout and ample paved, handicap-accessible parking.

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Flex Space with Digital Billboard
Flex Space with Digital Billboard

1009 E Interstate 2, Pharr, TX 78577

$1,795,000
6,241 sqft 0.76 AC lot

Flex space built in 2005 with central HVAC, digital billboard, and office plus warehouse/storage areas.

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Full-Service Restaurant Building
Full-Service Restaurant Building

2100 E Griffin Parkway, Mission, TX 78572

$750,000
4,620 sqft

Restaurant building with multiple dining areas, private rooms, and a commercial kitchen, suited for medical or office conversion.

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Storefront Property with Workshop
Storefront Property with Workshop

9717 N 10th Street, Mcallen, TX 78504

$990,000
7,560 sqft 0.94 AC lot

F1-zoned commercial space with central HVAC, ramp access, on-site parking, and potential for retail, medical, office, or service use.

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Corner Office Units
Corner Office Units

1022 E Griffin Parkway, Mission, TX 78572

$305,000
4,112 sqft 0.19 AC lot

Flexible professional suites offer dual access, a balcony, and a fire sprinkler system within a 2003 office development.

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Remodeled Corner Office Suite
Remodeled Corner Office Suite

733 N Ware Road, Mcallen, TX 78501

$650,000
3,000 sqft

Fully remodeled corner commercial unit with reception, 12 private offices, conference room, kitchen area, and two bathrooms.

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Office Units Building
Office Units Building

403 PIKE BLVD., Weslaco, TX 78596

$249,000
1,864 sqft 0.11 AC lot

Office units property on a 0.11-acre lot, built in 1983, located at 403 Pike Blvd in Weslaco, TX.

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Medical Office Building
Medical Office Building

104-b-1022 E Griffin Pkwy, Mission, TX 78572

$600,000
2,400 sqft

Medical office building with a reception lobby, exam/work stations, and both full and half bathrooms.

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Two-Story Child Care Facility with Balcony
Two-Story Child Care Facility with Balcony

411 N Glasscock Boulevard, Alton, TX 78573

$280,000
2,269 sqft 0.18 AC lot

Two-story state licensed child care facility on N Glasscock Boulevard, zoned C, with classroom and office space layout.

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Medical Office with MRI Room
Medical Office with MRI Room

902 S Airport Drive Unit 5A & 5B, Weslaco, TX 78596

$525,000
6,050 sqft

Previously operated as a medical office, featuring 12 patient rooms and an MRI room.

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Brick Office Building with Parking
Brick Office Building with Parking

108 N Nebraska Avenue, San Juan, TX 78589

$229,000
448 sqft 0.15 AC lot

Brick office building on C1 zoning with a parking lot, central HVAC, and electric water heater in San Juan.

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Downtown Mission Investment Opportunity
Downtown Mission Investment Opportunity

1122 N. Conway Ave, Palmhurst, TX 78572

$695,000
3,581 sqft 0.24 AC lot

Income-producing property with established tenants in Downtown Mission.

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Retail Property with Available Suite
Retail Property with Available Suite

515 E Business 83, Alamo, TX 78516

$1,450,000
14,050 sqft 0.90 AC lot

Two-suite commercial property with one occupied space and another available for leasing or owner use.

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Hidalgo County, TX Medical Office Space Market Trends and Statistics

Explore 72 medical office space for sale in Hidalgo County, TX, showcased through 62 active listings on our real estate platform. These investment opportunities span a total of 385,503 square feet of properties for sale, with an estimated market value of $41,504,392.

Sale prices for medical spaces in Hidalgo County, TX start at $229,000, averaging $988,199, and reaching up to $2,389,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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