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    Weslaco, TX Medical Office Space for Sale

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    Medical Office Plaza Building
    Updated: Jun 6
    Medical Office Plaza Building

    1125 James Street, Weslaco, TX 78596

    $2,389,000
    19,200 sqft 1.75 AC lot
    19,200 sq ft plaza on 1.75 acres offers significant space and land.
    Located in the fast‑growing city of Weslaco, TX, in the heart of the medical industry.
    Potential to earn $30,000+ per month by leasing out the entire plaza.
    Priced at less than $130 per sq ft, representing a competitive value.
    Partially leased, providing immediate income potential and flexibility to customize.
    View details
    Weslaco Commercial Property For Sale
    Updated: Feb 16
    Weslaco Commercial Property For Sale

    403 PIKE BLVD., Weslaco, TX 78596

    $249,000
    1,864 sqft 0.11 AC lot
    High‑visibility location in a high‑traffic area.
    Versatile layout suitable for multiple business uses.
    Ideal for medical office, insurance agency, or professional services.
    Strong exposure and easy access.
    Surrounded by established businesses and convenient amenities.
    View details
    Two Single-Story Office Buildings
    Two Single-Story Office Buildings

    1102 S Airport Dr, Weslaco, TX 78596

    $2,200,000
    11,556 sqft 1.04 AC lot

    Income-producing office property with two single-story buildings occupied by two tenants and B-1 zoning.

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    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Multi-Office Care and Education Facility
    Multi-Office Care and Education Facility

    1110 S Airport Drive, Weslaco, TX 78596

    $2,199,000
    17,375 sqft

    Flexible room and office layout with waiting and reception areas, multiple restrooms, and outdoor space with paved parking.

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    Office Condo Suite with Parking
    Office Condo Suite with Parking

    505 Angelita Dr Unit 3, Weslaco, TX 78596

    $299,500
    3,038 sqft

    Professionally designed 3,038 SF office condo suite built in 2005, with on-site parking and flexible layout for office use.

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    Medical Office with MRI Room
    Medical Office with MRI Room

    902 S Airport Drive Unit 5A & 5B, Weslaco, TX 78596

    $525,000
    6,050 sqft

    Previously operated as a medical office, featuring 12 patient rooms and an MRI room.

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    Weslaco Plaza for Sale
    Weslaco Plaza for Sale

    1125 James Street, Weslaco, TX 78596

    $2,389,000
    19,200 sqft 1.75 AC lot

    19,200 SF plaza on 1.75 acres in Weslaco, TX.

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    Commercial Building Near Interstate Highway
    Commercial Building Near Interstate Highway

    1420 E Interstate Hwy 2, Weslaco, TX 78596

    $1,500,000
    7,348 sqft

    Commercial block/stucco building with metal roof, easy highway access.

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 8 Active listings in Weslaco, TX, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 64 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Pharr Commercial Building For Sale
    Pharr Commercial Building For Sale

    1009 E Interstate 2, Pharr, TX 78577

    $1,795,000
    6,241 sqft 0.76 AC lot

    Commercial building with high traffic, strong exposure, and endless potential.

    View details
    Brick Retail Office Building
    Brick Retail Office Building

    108 N Nebraska Ave, San Juan, TX 78589

    $229,000
    448 sqft

    Brick building on a parking lot with C-1 zoning in a well-trafficked business area along Nebraska Ave.

    View details
    Commercial Land with Non-Livable Structure
    Commercial Land with Non-Livable Structure

    701 E Sgt. Leonel Trevino Road, San Juan, TX 78589

    $429,000
    1,482 sqft 5.17 AC lot

    For sale commercial land with a non-livable structure and survey availability, located with access to major regional amenities.

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    Commercial Building with High Visibility
    Commercial Building with High Visibility

    1009 E Interstate 2, Pharr, TX 78577

    $1,795,000
    6,241 sqft

    Commercial building with high traffic, strong exposure, and endless potential.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Lot in McAllen
    Prime Commercial Lot in McAllen

    4029 Expressway 83, Mcallen, TX 78501

    $1,300,000
    0.95 AC lot

    Vacant commercial lot with high visibility and traffic exposure.

    View details
    Development Land at Major Intersection
    Development Land at Major Intersection

    6801 Saratoga, Corpus Christi, TX 78414

    $6,250,000
    15.48 AC lot

    For sale development land at the Airline Road and Saratoga Boulevard intersection with utilities available nearby.

    View details
    Prime Commercial Lot Available
    Prime Commercial Lot Available

    7151 Williams DR, Corpus Christi, TX 78412

    $1,945,000
    3.00 AC lot

    Over 3-acre commercial lot at a busy intersection.

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    Land
    Land

    2778 FM 236, Victoria, TX 77905

    $419,885
    5.93 AC lot

    Commercial land · 5.93 Acres

    View details

    Off-Market Properties in Weslaco, TX

    Consider similar Off-Market properties in Weslaco, TX. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    901 6th St
    MEDICAL BUILDING

    901 6th St, Weslaco, TX 78596-4202

    $550,000
    Estimated value
    9,020 sqft 1.17 AC lot
    View details
    1412 8th St
    MEDICAL BUILDING

    1412 8th St, Weslaco, TX 78596-6639

    Value Estimation by Request
    5,328 sqft 0.66 AC lot
    View details
    1220 6th St
    MEDICAL BUILDING

    1220 6th St, Weslaco, TX 78596-6420

    Value Estimation by Request
    3,785 sqft 0.23 AC lot
    View details
    1810 8th St
    MEDICAL BUILDING

    1810 8th St, Weslaco, TX 78596-6648

    Value Estimation by Request
    1,984 sqft 1.01 AC lot
    View details
    1525 6th St
    MEDICAL BUILDING

    1525 6th St, Weslaco, TX 78596-4666

    Value Estimation by Request
    1,588 sqft 0.16 AC lot
    View details
    1210 8th St Ste, Unit 4
    MEDICAL BUILDING

    1210 8th St Ste, Weslaco, TX 78596-7120

    Unit 4
    Value Estimation by Request
    1,250 sqft 0.28 AC lot
    View details
    1311 6th St
    MEDICAL BUILDING

    1311 6th St, Weslaco, TX 78596-6601

    Value Estimation by Request
    5,328 sqft 0.56 AC lot
    View details
    1216 6th St
    MEDICAL BUILDING

    1216 6th St, Weslaco, TX 78596-6420

    Value Estimation by Request
    2,052 sqft 0.19 AC lot
    View details
    1710 8th St
    MEDICAL BUILDING

    1710 8th St, Weslaco, TX 78596-6646

    $575,000
    Estimated value
    7,391 sqft 1.01 AC lot
    View details
    3202 Expy 83
    MEDICAL BUILDING

    3202 Expy 83, Weslaco, TX 78599-5519

    $1,395,000
    Estimated value
    9,960 sqft 0.91 AC lot
    View details
    1001 Rone Dr
    MEDICAL BUILDING

    1001 Rone Dr, Weslaco, TX 78596-4843

    $1,510,000
    Estimated value
    11,035 sqft 0.96 AC lot
    View details
    1515 6th St
    MEDICAL BUILDING

    1515 6th St, Weslaco, TX 78596

    $720,000
    Estimated value
    11,064 sqft 1.06 AC lot
    View details
    1210 8th St Ste, Unit 2
    MEDICAL BUILDING

    1210 8th St Ste, Weslaco, TX 78596-7120

    Unit 2
    Value Estimation by Request
    1,910 sqft 0.24 AC lot
    View details
    1002 Expy 83
    MEDICAL BUILDING

    1002 Expy 83, Weslaco, TX 78596-4523

    $540,000
    Estimated value
    7,500 sqft 1.07 AC lot
    View details
    Fm 1015
    MEDICAL BUILDING

    Fm 1015, Weslaco, TX 78599

    Value Estimation by Request
    2,288 sqft 0.54 AC lot
    View details
    1210 8th St Ste 1a
    MEDICAL BUILDING

    1210 8th St Ste 1a, Weslaco, TX 78596-7120

    Value Estimation by Request
    2,279 sqft 0.30 AC lot
    View details

    Weslaco, TX Medical Office Space Market Trends and Statistics

    Explore 72 medical office space for sale in Weslaco, TX, showcased through 8 active listings on our real estate platform. These investment opportunities span a total of 85,631 square feet of properties for sale, with an estimated market value of $11,750,500.

    Sale prices for medical spaces in Weslaco, TX start at $249,000, averaging $1,468,812, and reaching up to $2,389,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 25
    Medical Office Space 17
    Office buildings 10

    Demographics Overview

    Population 74K
    Population Growth (5Y) -40.9%
    Median Household Income $54,817
    College Educated 23.8%

    High-Yield Neighborhoods for Investment

    Identify Weslaco submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    78596 $1.7M

    Taxes & Financing

    Tax Rate (average for all types) 2.50%
    Property Tax per SF $36.86 per SF
    Tax Rate vs County Average 0.13 pp above county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Hidalgo County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Hidalgo County

    Retail

    Office

    Residential Income

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