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Weslaco, TX Medical Office Space for Sale

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7 results
Weslaco Plaza for Sale
$2,395,000
19,200 SF

Weslaco Plaza for Sale

1125 James Street, Weslaco, TX 78596

19,200 SF plaza on 1.75 acres in Weslaco, TX.

  • 19,200 sq ft plaza on 1.75 acres offers significant space and land.
  • Located in the fast‑growing city of Weslaco, TX, in the heart of the medical industry.
  • Potential to earn $30,000+ per month by leasing out the entire plaza.
  • Priced at less than $130 per sq ft, representing a competitive value.
  • Partially leased, providing immediate income potential and flexibility to customize.
Updated: Dec 29, 2025
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Weslaco Commercial Property For Sale
$249,000
1,864 SF

Weslaco Commercial Property For Sale

403 PIKE BLVD., Weslaco, TX 78596

Commercial property in high-traffic area, ideal for various businesses.

  • High‑visibility location in a high‑traffic area.
  • Versatile layout suitable for multiple business uses.
  • Ideal for medical office, insurance agency, or professional services.
  • Strong exposure and easy access.
  • Surrounded by established businesses and convenient amenities.
Updated: Feb 16
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Weslaco Commercial Pad Site
Contact for pricing

Weslaco Commercial Pad Site

Master-planned commercial development site at a prominent Weslaco intersection.

SW CORNER PIKE BLVD & FM 1015 INTERNATIONAL, Weslaco, TX 78596
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Weslaco Plaza for Sale
$2,395,000
19,200 SF

Weslaco Plaza for Sale

19,200 SF plaza on 1.75 acres in Weslaco, TX.

1125 James Street, Weslaco, TX 78596
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Medical Plaza in Weslaco, TX
$2,395,000
19,200 SF

Medical Plaza in Weslaco, TX

19,200 SF medical plaza in a fast-growing city.

1125 James Street, Weslaco, TX 78596
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Commercial Building Near Interstate Highway
$1,500,000
7,348 SF

Commercial Building Near Interstate Highway

Commercial block/stucco building with metal roof, easy highway access.

1420 E Interstate Hwy 2, Weslaco, TX 78596
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Commercial Building Near Interstate Highway
$1,500,000
7,348 SF

Commercial Building Near Interstate Highway

Commercial block/stucco building with easy highway access and ample parking.

1420 Interstate 2 Highway, Weslaco, TX 78596
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Based on your search, we've compiled 85 Potential Opportunities for your consideration. Besides 7 Active listings in Weslaco, TX, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 70 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

36,186 SF Office / Medical | Pharr TX 78577
$3,800,000
36,186 SF

36,186 SF Office / Medical | Pharr TX 78577

36,186 SF Office / Medical | Pharr TX 78577

1503 W Polk Ave., Pharr, TX 78577
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Prime Commercial Tract For Sale
$1,150,000

Prime Commercial Tract For Sale

1.66-acre commercial tract with high visibility and expressway frontage.

330 North Mile 1 East, Mercedes, TX 78570
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2,324 Medical Building For Sale
$89,000
2,324 SF

2,324 Medical Building For Sale

2,324 Medical Building For Sale

520 W 3rd Street, Mercedes, TX 78570
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Medical Office with Retail Potential
$490,000
3,311 SF

Medical Office with Retail Potential

Large corner property suitable for medical or retail use.

615 S Aster Street, Pharr, TX 78577
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Commercial Lot in McAllen
$1,300,000
0.95 Acres

Prime Commercial Lot in McAllen

Vacant commercial lot with high visibility and traffic exposure.

4029 Expressway 83, Mcallen, TX 78501
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Prime Development Land For Sale
$6,250,000
15.48 Acres

Prime Development Land For Sale

15.48 acres of land suitable for various development projects.

6801 Saratoga, Corpus Christi, TX 78414
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Prime Commercial Lot Near Leopard
$250,000
1.93 Acres

Prime Commercial Lot Near Leopard

1.93-acre commercial lot behind Stripes at Leopard & McKinzie.

Leopard lot: 5, Corpus Christi, TX 78410
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Prime Commercial Lot in Victoria
$299,900

Prime Commercial Lot in Victoria

One-acre commercial lot in growing business park, ideal for development.

205 Kerh Blvd, Victoria, TX 77904
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Explore Off-Market Properties in Weslaco, TX

Consider similar Off-Market properties in Weslaco, TX. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

901 6th St

901 6th St

MEDICAL BUILDING • 9,020 SF
Value Estimation
$550,000
901 6th St, Weslaco, TX 78596-4202
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1412 8th St

1412 8th St

MEDICAL BUILDING • 5,328 SF
Value Estimation by Request
1412 8th St, Weslaco, TX 78596-6639
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1220 6th St

1220 6th St

MEDICAL BUILDING • 3,785 SF
Value Estimation by Request
1220 6th St, Weslaco, TX 78596-6420
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1810 8th St

1810 8th St

MEDICAL BUILDING • 1,984 SF
Value Estimation by Request
1810 8th St, Weslaco, TX 78596-6648
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1525 6th St

1525 6th St

MEDICAL BUILDING • 1,588 SF
Value Estimation by Request
1525 6th St, Weslaco, TX 78596-4666
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1210 8th St Ste, Unit 4

1210 8th St Ste, Unit 4

MEDICAL BUILDING • 1,250 SF
Value Estimation by Request
1210 8th St Ste, Weslaco, TX 78596-7120
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1311 6th St

1311 6th St

MEDICAL BUILDING • 5,328 SF
Value Estimation by Request
1311 6th St, Weslaco, TX 78596-6601
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1216 6th St

1216 6th St

MEDICAL BUILDING • 2,052 SF
Value Estimation by Request
1216 6th St, Weslaco, TX 78596-6420
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1710 8th St

1710 8th St

MEDICAL BUILDING • 7,391 SF
Value Estimation
$575,000
1710 8th St, Weslaco, TX 78596-6646
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3202 Expy 83

3202 Expy 83

MEDICAL BUILDING • 9,960 SF
Value Estimation
$1,395,000
3202 Expy 83, Weslaco, TX 78599-5519
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1001 Rone Dr

1001 Rone Dr

MEDICAL BUILDING • 11,035 SF
Value Estimation
$1,510,000
1001 Rone Dr, Weslaco, TX 78596-4843
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1515 6th St

1515 6th St

MEDICAL BUILDING • 11,064 SF
Value Estimation
$720,000
1515 6th St, Weslaco, TX 78596
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1210 8th St Ste, Unit 2

1210 8th St Ste, Unit 2

MEDICAL BUILDING • 1,910 SF
Value Estimation by Request
1210 8th St Ste, Weslaco, TX 78596-7120
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1002 Expy 83

1002 Expy 83

MEDICAL BUILDING • 7,500 SF
Value Estimation
$540,000
1002 Expy 83, Weslaco, TX 78596-4523
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Fm 1015

Fm 1015

MEDICAL BUILDING • 2,288 SF
Value Estimation by Request
Fm 1015, Weslaco, TX 78599
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1210 8th St Ste 1a

1210 8th St Ste 1a

MEDICAL BUILDING • 2,279 SF
Value Estimation by Request
1210 8th St Ste 1a, Weslaco, TX 78596-7120
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1015 Utah Ave

1015 Utah Ave

MEDICAL BUILDING • 3,267 SF
Value Estimation by Request
1015 Utah Ave, Weslaco, TX 78596-5588
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Weslaco, TX Medical Office Space Investment Opportunities Market Analysis

Explore 77 medical office space for sale in Weslaco, TX, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 1,879,815 square feet of properties for sale, with an estimated market value of $27,109,000.

Sale prices for medical spaces in Weslaco, TX start at $249,000, averaging $423,578, and reaching up to $2,395,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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