For Sale
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Property Types
  • Retail
  • Office
  • Residential Income
  • Restaurants
  • Industrial
  • Mixed-Use
  • Hospitality
  • Health Care
  • Sports & Entertainment
  • Land
  • Agricultural
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Durham County, NC Medical Offices for Sale

7 results
List
Map
Colonial Square Office/Medical Building
$3,499,000
21,532 SF

Colonial Square Office/Medical Building

4400 Ben Franklin Blvd, Durham, NC 27704

Multi-functional commercial building in Durham's Independence Park.

  • Significant income generation from leased area: $227,739 in 2024.
  • Large, multi‑functional commercial building with 21,532 total square feet.
  • Located in a sought‑after office/medical park in northern Durham County.
  • Flexible space suitable for various professional uses (medical, office, education, law).
  • Features include an elevator, ample storage, and a loading dock.
Updated: Aug 8, 2025
View details
Durham Office Near Highway 85
$750,000
1,600 SF

Durham Office Near Highway 85

3219 Guess Rd, Durham, NC 27705

Office property close to Highway 85, Duke, and RTP.

  • Convenient location near Hwy 85, Duke University, and Research Triangle Park (RTP).
  • Suitable for business or residential use.
  • High‑visibility road frontage on Guess Road.
  • Half‑acre lot.
  • Potential for home occupation.
Updated: May 26, 2025
View details
Morrisville Office Building - Class A
Contact for pricing
35,350 SF

Morrisville Office Building - Class A

35,350 SF Office, Prime Location, Vacant

703 Slater Rd, Morrisville, NC 27560
View details
Durham Medical Office Condos
Contact for pricing
41,588 SF

Durham Medical Office Condos

Three Class A condos, 2024 renovation

4020 Roxboro St, Durham, NC 27704
View details
Durham Medical Office Condo
$850,000
3,037 SF

Durham Medical Office Condo

Prime Medical Space, 3,037 SF, $850K

249 Nc Highway 54, Durham, NC 27713
View details
Southpoint Medical Office Investment
$2,995,000
8,986 SF

Southpoint Medical Office Investment

Durham, NC Medical Office Building - High Occupancy

249 Nc Hwy 54- –, Durham, NC 27713
View details
Hayti District Office Complex
$8,000,000
9,000 SF

Hayti District Office Complex

Prime Durham location, 9,000 sq ft, vacant.

601 Fayetteville St, Durham, NC 27701
View details
Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 7 Active listings in Durham County, NC, we suggest exploring several alternatives: similar 9 Off-Market properties to explore as potential leads

Explore Off-Market Properties in Durham County, NC

Consider similar Off-Market properties in Durham County, NC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

3026 Old Chapel Hill Rd

3026 Old Chapel Hill Rd

Medical offices • 3,935 SF
Value Estimation by Request
3026 Old Chapel Hill Rd, Durham, NC 27707
View details
703 Slater Rd

703 Slater Rd

Medical offices • 35,350 SF
Value Estimation by Request
703 Slater Rd, Morrisville, NC 27560
View details
5306-102 Hwy

5306-102 Hwy

Medical offices • 2,028 SF
Value Estimation by Request
5306-102 Hwy, Durham, NC 27713
View details
249 Nc Hwy 54- –

249 Nc Hwy 54- –

Medical offices • 8,986 SF
Value Estimation by Request
249 Nc Hwy 54- –, Durham, NC 27713
View details
5915 Farrington Rd

5915 Farrington Rd

Medical offices • 5,622 SF
Value Estimation by Request
5915 Farrington Rd, Chapel Hill, NC 27517
View details
249 Nc Highway 54

249 Nc Highway 54

Medical offices • 3,037 SF
Value Estimation by Request
249 Nc Highway 54, Durham, NC 27713
View details
1804 Martin Luther King Jr Pkwy

1804 Martin Luther King Jr Pkwy

Medical offices • 9,992 SF
Value Estimation by Request
1804 Martin Luther King Jr Pkwy, Durham, NC 27707
View details
4210 Roxboro St

4210 Roxboro St

Medical offices • 2,408 SF
Value Estimation by Request
4210 Roxboro St, Durham, NC 27704
View details
249 Nc Highway 54

249 Nc Highway 54

Medical offices • 3,037 SF
Value Estimation by Request
249 Nc Highway 54, Durham, NC 27713
View details

Durham County, NC Medical Offices Investment Opportunities Market Analysis

Explore 16 medical offices for sale in Durham County, NC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 169,884 square feet of properties for sale, with an estimated market value of $11,499,000.

Prices for medical spaces in Durham County, NC start at $3,499,000, averaging $5,749,500, and reaching up to $8,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

List
Map