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Missouri Medical Offices for Sale

82 results
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Renovated Downtown Commercial Property
$550,000
4,548 SF

Renovated Downtown Commercial Property

224 N Frederick St, Cape Girardeau, MO 63701

Versatile, renovated 11-bedroom property in downtown Cape Girardeau, Missouri.

  • Prime downtown location steps from dining, shopping, and campus.
  • Proven income‑producing property as a high‑demand sorority house.
  • Fully renovated in 2020 with 11 bedrooms and over 5,100 square feet.
  • Versatile property suitable for group housing, student rentals, or professional office space.
  • Generous lot with twenty‑five parking spaces.
Updated: Jan 9
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Versatile Trenton Building with Potential
$125,000
0.11 Acres

Versatile Trenton Building with Potential

152 E 8Th St, Trenton, MO 64683

Adaptable building suitable for residential, commercial, or live/work use.

  • Residential Zoning allows transformation into a unique home.
  • Potential for a live/work setup.
  • Full basement offers options for additional living space or business use.
  • Forced‑air furnace and central air provide year‑round comfort.
  • Ample parking available.
Updated: Oct 17, 2025
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Medical Office Building For Sale
$2,750,000
2.51 Acres

Medical Office Building For Sale

Medical office building on 2.51 acres with expansion potential.

3904 Beck Rd, St Joseph, MO 64506
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Veterinary Clinic on Belt Highway
$399,000
0.70 Acres

Veterinary Clinic on Belt Highway

2496 SF veterinary clinic on a large 0.7-acre lot.

3111 N Belt Hwy, St Joseph, MO 64506
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Versatile Commercial Building in Clinton
$765,000
1.40 Acres

Versatile Commercial Building in Clinton

Well-maintained commercial building with multiple uses in Clinton's business district.

209 S 2Nd St, Clinton, MO 64735
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Prime Office Condo Opportunity
Pending
$450,000
0.05 Acres

Prime Office Condo Opportunity

Well-located office/medical condo in Lee's Summit business corridor.

232 NE Tudor Rd, Lees Summit, MO 64086
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Independence Commercial Building For Sale
$365,000
0.28 Acres

Independence Commercial Building For Sale

3,456 SF commercial building on high-traffic corner lot.

13717 E 39Th St, Independence, MO 64055
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Blue Springs Commercial Flex Space
$525,000
0.08 Acres

Blue Springs Commercial Flex Space

Commercial space with flexibility, suitable for medical or office use.

1900 NW Copper Oaks Cir, Blue Springs, MO 64015
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Ste Genevieve Mixed-Use Building
$450,000
8,170 SF

Ste Genevieve Mixed-Use Building

All-brick commercial building with drive-thru, ideal for various businesses.

930 Park Dr, Ste Genevieve, MO 63670
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Mound City Commercial Building
$225,000
1.00 Acre

Mound City Commercial Building

Affordable commercial building suitable for office, retail, or medical use.

1105 State St, Mound City, MO 64470
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Steelville Commercial Building For Sale
$87,000
1,350 SF

Steelville Commercial Building For Sale

Commercial building with potential for various business uses.

204 W Main St, Steelville, MO 65565
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St. Peters Standalone Office Building
$600,000
0.38 Acres

St. Peters Standalone Office Building

3,000 SF office building suitable for medical or professional use.

410 Jungermann Rd, St Peters, MO 63376
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Cape Girardeau Commercial Property
Pending
$825,000
7,000 SF

Cape Girardeau Commercial Property

Well-maintained commercial property with over 7,000 square feet.

340 S Broadview St, Cape Girardeau, MO 63703
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Downtown Branson Building on Large Lot
$499,000
1.83 Acres

Downtown Branson Building on Large Lot

34,000 SF building on 1.83 acres in downtown Branson.

610 S 6Th St, Branson, MO 65616
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Versatile Building Near Highway 65
$350,000
0.46 Acres

Versatile Building Near Highway 65

Adaptable building suitable for medical, retail, or office use.

1011 W Main St, Buffalo, MO 65622
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Republic Commercial Office Space Available
$789,900
0.64 Acres

Republic Commercial Office Space Available

Versatile office space suitable for various professional service providers.

820 S Illinois Ave, Republic, MO 65738
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Versatile Commercial Space Near Hospital
$1,050,000
10,800 SF

Versatile Commercial Space Near Hospital

Adaptable commercial building near medical facilities and Cunningham Park.

2702 Cunningham Ave, Joplin, MO 64804
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Carthage Commercial Property For Sale
$699,000
4,948 SF

Carthage Commercial Property For Sale

Versatile commercial building suitable for medical, retail, office, or investment.

327 E Airport Dr, Carthage, MO 64836
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Former Dental Office For Sale
$500,000
3,600 SF

Former Dental Office For Sale

Freestanding 3,600 SF commercial building suitable for medical or office use.

3121 Mc Clelland Blvd, Joplin, MO 64804
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VALUE-ADD MEDICAL & PROFESSIONAL BUILDING
Contact for pricing
84,716 SF

VALUE-ADD MEDICAL & PROFESSIONAL BUILDING

VALUE-ADD MEDICAL & PROFESSIONAL BUILDING - Subject To Offer

1905 W. 32nd Street, Joplin, MO 64804
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Columbia Medical Office Portfolio
Contact for pricing
41,509 SF

Columbia Medical Office Portfolio

Three Class A Medical Buildings, 41,509 SF

812 Keene St, Columbia, MO 65201
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LaHarpe Center: Prime Office Investment
$510,000
12,000 SF

LaHarpe Center: Prime Office Investment

12,000 SF Office Building, Multi-Tenant, Net Lease

2000 La Harpe St, Kirksville, MO 63501
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Odessa Commercial Building - $1.48M
$1,480,000
37,000 SF

Odessa Commercial Building - $1.48M

37,000 SF Vacant Building, Multiple Uses

1212 Us Highway 40, Odessa, MO 64076
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Missouri Medical Offices Investment Opportunities Market Analysis

Explore 1722 medical offices for sale in Missouri, showcased through 82 active listings on our real estate platform. These investment opportunities span a total of 65,389,448 square feet of properties for sale, with an estimated market value of $486,323,785.

Prices for medical spaces in Missouri start at $75,000, averaging $562,874, and reaching up to $11,990,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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