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    Missouri Medical Offices for Sale

    82 results
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    Renovated Downtown Commercial Property
    $550,000
    4,548 SF

    Renovated Downtown Commercial Property

    224 N Frederick St, Cape Girardeau, MO 63701

    Versatile, renovated 11-bedroom property in downtown Cape Girardeau, Missouri.

    • Prime downtown location steps from dining, shopping, and campus.
    • Proven income‑producing property as a high‑demand sorority house.
    • Fully renovated in 2020 with 11 bedrooms and over 5,100 square feet.
    • Versatile property suitable for group housing, student rentals, or professional office space.
    • Generous lot with twenty‑five parking spaces.
    Updated: Jan 9
    View details
    Versatile Trenton Building with Potential
    $125,000
    0.11 Acres

    Versatile Trenton Building with Potential

    152 E 8Th St, Trenton, MO 64683

    Adaptable building suitable for residential, commercial, or live/work use.

    • Residential Zoning allows transformation into a unique home.
    • Potential for a live/work setup.
    • Full basement offers options for additional living space or business use.
    • Forced‑air furnace and central air provide year‑round comfort.
    • Ample parking available.
    Updated: Oct 17, 2025
    View details
    Medical Office Building For Sale
    $2,750,000
    2.51 Acres

    Medical Office Building For Sale

    Medical office building on 2.51 acres with expansion potential.

    3904 Beck Rd, St Joseph, MO 64506
    View details
    Veterinary Clinic on Belt Highway
    $399,000
    0.70 Acres

    Veterinary Clinic on Belt Highway

    2496 SF veterinary clinic on a large 0.7-acre lot.

    3111 N Belt Hwy, St Joseph, MO 64506
    View details
    Versatile Commercial Building in Clinton
    $765,000
    1.40 Acres

    Versatile Commercial Building in Clinton

    Well-maintained commercial building with multiple uses in Clinton's business district.

    209 S 2Nd St, Clinton, MO 64735
    View details
    Prime Office Condo Opportunity
    Pending
    $450,000
    0.05 Acres

    Prime Office Condo Opportunity

    Well-located office/medical condo in Lee's Summit business corridor.

    232 NE Tudor Rd, Lees Summit, MO 64086
    View details
    Independence Commercial Building For Sale
    $365,000
    0.28 Acres

    Independence Commercial Building For Sale

    3,456 SF commercial building on high-traffic corner lot.

    13717 E 39Th St, Independence, MO 64055
    View details
    Blue Springs Commercial Flex Space
    $525,000
    0.08 Acres

    Blue Springs Commercial Flex Space

    Commercial space with flexibility, suitable for medical or office use.

    1900 NW Copper Oaks Cir, Blue Springs, MO 64015
    View details
    Ste Genevieve Mixed-Use Building
    $450,000
    8,170 SF

    Ste Genevieve Mixed-Use Building

    All-brick commercial building with drive-thru, ideal for various businesses.

    930 Park Dr, Ste Genevieve, MO 63670
    View details
    Mound City Commercial Building
    $225,000
    1.00 Acre

    Mound City Commercial Building

    Affordable commercial building suitable for office, retail, or medical use.

    1105 State St, Mound City, MO 64470
    View details
    Steelville Commercial Building For Sale
    $87,000
    1,350 SF

    Steelville Commercial Building For Sale

    Commercial building with potential for various business uses.

    204 W Main St, Steelville, MO 65565
    View details
    St. Peters Standalone Office Building
    $600,000
    0.38 Acres

    St. Peters Standalone Office Building

    3,000 SF office building suitable for medical or professional use.

    410 Jungermann Rd, St Peters, MO 63376
    View details
    Cape Girardeau Commercial Property
    Pending
    $825,000
    7,000 SF

    Cape Girardeau Commercial Property

    Well-maintained commercial property with over 7,000 square feet.

    340 S Broadview St, Cape Girardeau, MO 63703
    View details
    Downtown Branson Building on Large Lot
    $499,000
    1.83 Acres

    Downtown Branson Building on Large Lot

    34,000 SF building on 1.83 acres in downtown Branson.

    610 S 6Th St, Branson, MO 65616
    View details
    Versatile Building Near Highway 65
    $350,000
    0.46 Acres

    Versatile Building Near Highway 65

    Adaptable building suitable for medical, retail, or office use.

    1011 W Main St, Buffalo, MO 65622
    View details
    Republic Commercial Office Space Available
    $789,900
    0.64 Acres

    Republic Commercial Office Space Available

    Versatile office space suitable for various professional service providers.

    820 S Illinois Ave, Republic, MO 65738
    View details
    Versatile Commercial Space Near Hospital
    $1,050,000
    10,800 SF

    Versatile Commercial Space Near Hospital

    Adaptable commercial building near medical facilities and Cunningham Park.

    2702 Cunningham Ave, Joplin, MO 64804
    View details
    Carthage Commercial Property For Sale
    $699,000
    4,948 SF

    Carthage Commercial Property For Sale

    Versatile commercial building suitable for medical, retail, office, or investment.

    327 E Airport Dr, Carthage, MO 64836
    View details
    Former Dental Office For Sale
    $500,000
    3,600 SF

    Former Dental Office For Sale

    Freestanding 3,600 SF commercial building suitable for medical or office use.

    3121 Mc Clelland Blvd, Joplin, MO 64804
    View details
    VALUE-ADD MEDICAL & PROFESSIONAL BUILDING
    Contact for pricing
    84,716 SF

    VALUE-ADD MEDICAL & PROFESSIONAL BUILDING

    VALUE-ADD MEDICAL & PROFESSIONAL BUILDING - Subject To Offer

    1905 W. 32nd Street, Joplin, MO 64804
    View details
    Columbia Medical Office Portfolio
    Contact for pricing
    41,509 SF

    Columbia Medical Office Portfolio

    Three Class A Medical Buildings, 41,509 SF

    812 Keene St, Columbia, MO 65201
    View details
    LaHarpe Center: Prime Office Investment
    $510,000
    12,000 SF

    LaHarpe Center: Prime Office Investment

    12,000 SF Office Building, Multi-Tenant, Net Lease

    2000 La Harpe St, Kirksville, MO 63501
    View details
    Odessa Commercial Building - $1.48M
    $1,480,000
    37,000 SF

    Odessa Commercial Building - $1.48M

    37,000 SF Vacant Building, Multiple Uses

    1212 Us Highway 40, Odessa, MO 64076
    View details

    Missouri Medical Offices Investment Opportunities Market Analysis

    Explore 1722 medical offices for sale in Missouri, showcased through 82 active listings on our real estate platform. These investment opportunities span a total of 65,389,448 square feet of properties for sale, with an estimated market value of $486,323,785.

    Prices for medical spaces in Missouri start at $75,000, averaging $562,874, and reaching up to $11,990,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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