Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Columbia, MO Medical Office Space for Sale

    Notify Me
    List
    Map
    Saint Louis, MO Kansas City, MO Louis, MO
    Keene Medical Corridor Office Portfolio
    Contact for pricing
    41,509 SF

    Keene Medical Corridor Office Portfolio

    812 N Keene St, Columbia, MO 65201

    Medical office portfolio in Keene Medical Corridor available for sale.

    • Three well‑maintained brick buildings.
    • Located in the highly desirable Keene Medical Corridor.
    • Ideal for owner occupants or investors.
    • Immediate proximity to Interstate 70 & Highway 63 interchange.
    • Medical office portfolio available for sale.
    Updated: Feb 12, 2025
    View details
    Medical Office Space Available
    $2,500,000
    8,451 SF

    Medical Office Space Available

    525 N Keene St, Columbia, MO 65201

    Class A medical office space in Columbia's Medical District.

    • 8,451 SF of Class A medical office space
    • Located in Columbia’s Premiere Medical District on Keene St.
    • Sale‑leaseback or owner‑user opportunity
    • Currently operated by Neurology, Inc., backed by Jefferson City Medical Group (JCMG)
    • Built in 2013
    Updated: Jan 26, 2024
    View details
    Columbia Medical Office Condominiums
    $1,792,885
    9,086 SF

    Columbia Medical Office Condominiums

    Medical office condominiums for sale or lease in Columbia, Missouri.

    500 N Keene St, Columbia, MO 65201
    View details
    Based on your search, we've compiled 84 Potential Opportunities for your consideration. Besides 3 Active listings in Columbia, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 73 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Union Missouri Medical Investment Opportunity
    $3,210,000
    14,592 SF

    Union Missouri Medical Investment Opportunity

    Medical office for sale with long-term lease and annual increases.

    1935 Prairie Dell Rd, Union, MO 63084
    View details
    Freestanding Retail Building For Sale/Lease
    Contact for pricing
    34,132 SF

    Freestanding Retail Building For Sale/Lease

    Versatile 34,132 SF retail building in prime location.

    1614 N Green St, Kirksville, MO 63501
    View details
    Mercy Health Clinic For Sale
    $3,210,000
    14,592 SF

    Mercy Health Clinic For Sale

    Mercy Health Clinic For Sale

    1935 Prairie Dell Rd, Union, MT 63084
    View details
    Kirksville Office Space For Sale
    Contact for pricing
    12,000 SF

    Kirksville Office Space For Sale

    12,000 SF office space in Kirksville, Missouri.

    2000 E La Harpe St, Kirksville, MO 63501
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Lake St. Louis Development Site
    $2,763,882
    12.69 Acres

    Lake St. Louis Development Site

    12.69-acre commercial land near planned Costco.

    Lot 7 Hawk Ridge Circle, Lake St Louis, MO 63367
    View details
    Commercial Lot in High-Traffic Area
    $291,740
    0.80 Acres

    Commercial Lot in High-Traffic Area

    Commercial lot with high visibility and convenient highway access.

    2 Cedric Station, Cedar Hill, MO 63016
    View details
    Medical Office Building For Sale
    $4,000,000
    64,800 SF

    Medical Office Building For Sale

    64,800 SF medical office building on 4.3 acres.

    1 Professional Drive, Alton, IL 62002
    View details
    Commercial Lot in Prime Location
    $321,037
    1.18 Acres

    Commercial Lot in Prime Location

    1.18 acre commercial lot in Peculiar, Missouri.

    Main Street, Peculiar, MO 64078
    View details

    Explore Off-Market Properties in Columbia, MO

    Consider similar Off-Market properties in Columbia, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2703 Clark Ln

    2703 Clark Ln

    MEDICAL BUILDING • 15,186 SF
    Value Estimation
    $525,000
    2703 Clark Ln, Columbia, MO 65202-2432
    View details
    500 Keene St Ste, Unit 303

    500 Keene St Ste, Unit 303

    MEDICAL BUILDING • 3,532 SF
    Value Estimation by Request
    500 Keene St Ste, Columbia, MO 65201-8104
    View details
    105 Keene St

    105 Keene St

    MEDICAL BUILDING • 35,165 SF
    Value Estimation
    $1,320,000
    105 Keene St, Columbia, MO 65201-8377
    View details
    401 Keene St

    401 Keene St

    MEDICAL BUILDING • 23,286 SF
    Value Estimation
    $975,000
    401 Keene St, Columbia, MO 65201-6625
    View details
    210 Portland St

    210 Portland St

    MEDICAL BUILDING • 4,056 SF
    Value Estimation by Request
    210 Portland St, Columbia, MO 65201-8374
    View details
    100 Keene St

    100 Keene St

    MEDICAL BUILDING • 1,812 SF
    Value Estimation by Request
    100 Keene St, Columbia, MO 65201-6603
    View details
    9 Ww N Blvd

    9 Ww N Blvd

    MEDICAL BUILDING • 5,124 SF
    Value Estimation by Request
    9 Ww N Blvd, Columbia, MO 65203-2657
    View details
    402 Keene St

    402 Keene St

    MEDICAL BUILDING • 70,783 SF
    Value Estimation
    $2,765,000
    402 Keene St, Columbia, MO 65201-8369
    View details
    1627 Towne Dr

    1627 Towne Dr

    MEDICAL BUILDING • 1,365 SF
    Value Estimation by Request
    1627 Towne Dr, Columbia, MO 65202-2339
    View details
    1705 Stadium Blvd

    1705 Stadium Blvd

    MEDICAL BUILDING • 4,128 SF
    Value Estimation by Request
    1705 Stadium Blvd, Columbia, MO 65202-1305
    View details
    1605 Broadway

    1605 Broadway

    MEDICAL BUILDING • 67,188 SF
    Value Estimation
    $2,875,000
    1605 Broadway, Columbia, MO 65201-8023
    View details
    1601 Broadway

    1601 Broadway

    MEDICAL BUILDING • 56,800 SF
    Value Estimation
    $2,390,000
    1601 Broadway, Columbia, MO 65201-8020
    View details
    601 Nifong Blvd

    601 Nifong Blvd

    MEDICAL BUILDING • 2,997 SF
    Value Estimation by Request
    601 Nifong Blvd, Columbia, MO 65203-6804
    View details
    6080 Bass Ln

    6080 Bass Ln

    MEDICAL BUILDING • 6,860 SF
    Value Estimation by Request
    6080 Bass Ln, Columbia, MO 65201-9735
    View details
    3501 Berrywood Dr

    3501 Berrywood Dr

    MEDICAL BUILDING • 22,611 SF
    Value Estimation
    $1,475,000
    3501 Berrywood Dr, Columbia, MO 65201-6584
    View details
    811 Keene St

    811 Keene St

    MEDICAL BUILDING • 4,889 SF
    Value Estimation by Request
    811 Keene St, Columbia, MO 65201-6634
    View details
    500 Keene St Ste, Unit 402

    500 Keene St Ste, Unit 402

    MEDICAL BUILDING • 3,544 SF
    Value Estimation by Request
    500 Keene St Ste, Columbia, MO 65201-8104
    View details
    601 Nifong Blvd

    601 Nifong Blvd

    MEDICAL BUILDING • 2,564 SF
    Value Estimation by Request
    601 Nifong Blvd, Columbia, MO 65203-6804
    View details
    500 Keene St Ste, Unit 207

    500 Keene St Ste, Unit 207

    MEDICAL BUILDING • 3,761 SF
    Value Estimation by Request
    500 Keene St Ste, Columbia, MO 65201-8104
    View details
    500 Keene St Ste, Unit 102

    500 Keene St Ste, Unit 102

    MEDICAL BUILDING • 2,933 SF
    Value Estimation by Request
    500 Keene St Ste, Columbia, MO 65201-8104
    View details
    500 Keene St Ste, Unit 202

    500 Keene St Ste, Unit 202

    MEDICAL BUILDING • 1,195 SF
    Value Estimation by Request
    500 Keene St Ste, Columbia, MO 65201-8104
    View details

    Columbia, MO Medical Office Space Investment Opportunities Market Analysis

    Explore 76 medical office space for sale in Columbia, MO, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 3,245,543 square feet of properties for sale, with an estimated market value of $11,330,000.

    Sale prices for medical spaces in Columbia, MO start at $295,000, averaging $419,629, and reaching up to $650,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Medical Office Space for Sale Near Columbia, MO

    Popular Searches in Columbia, MO

    Popular Categories

    Most Searched ZIP Codes in Columbia, MO

    • 65201

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!