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    Columbia, MO
    Medical Premises

    Columbia, MO Medical Office Space for Sale

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    Centertown, MO Hallsville, MO Fulton, MO Rocheport, MO Harrisburg, MO Ashland, MO Hartsburg, MO Jamestown, MO
    Medical Office Space Available
    Updated: Jan 26, 2024
    Medical Office Space Available

    525 N Keene St, Columbia, MO 65201

    $2,500,000
    8,451 sqft
    8,451 SF of Class A medical office space
    Located in Columbia’s Premiere Medical District on Keene St.
    Sale‑leaseback or owner‑user opportunity
    Currently operated by Neurology, Inc., backed by Jefferson City Medical Group (JCMG)
    Built in 2013
    View details
    Keene Medical Corridor Office Portfolio
    Updated: Feb 12, 2025
    Keene Medical Corridor Office Portfolio

    812 N Keene St, Columbia, MO 65201

    Contact for pricing
    41,509 sqft
    Three well‑maintained brick buildings.
    Located in the highly desirable Keene Medical Corridor.
    Ideal for owner occupants or investors.
    Immediate proximity to Interstate 70 & Highway 63 interchange.
    Medical office portfolio available for sale.
    View details
    Columbia Medical Office Condominiums
    Columbia Medical Office Condominiums

    500 N Keene St, Columbia, MO 65201

    $1,792,885
    9,086 sqft

    Medical office condominiums for sale or lease in Columbia, Missouri.

    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 3 Active listings in Columbia, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 69 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Secured Parking Office Building
    Secured Parking Office Building

    5780 Osage Beach Parkway, Osage Beach, MO 65065

    $4,000,000
    1.60 AC lot

    Gateway Building offers Class A office space with secured covered parking, elevators with security systems, and 28,585 SF.

    View details
    Wentzville Medical Office Investment Opportunity
    Wentzville Medical Office Investment Opportunity

    1660 W Meyer Rd, Wentzville, MO 63385

    $2,100,000
    6,541 sqft

    Freestanding medical office building in booming Wentzville area.

    View details
    Medical/Office Building Near Hospital
    Medical/Office Building Near Hospital

    853 Medical Dr, Wentzville, MO 63385

    Contact for pricing
    15,366 sqft

    15,366 SF building 100% leased to high-quality tenants.

    View details
    Class A Office Building For Sale
    Class A Office Building For Sale

    5780 Osage Beach Parkway, Osage Beach, MO 65065

    $4,000,000
    3,028 sqft

    Class A office building near Lake Regional Hospital.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Building Lot with Highway Access
    Commercial Building Lot with Highway Access

    2 Cedric Station, Cedar Hill, MO 63016

    $291,740
    0.80 AC lot

    Build-to-suit commercial site near Highway 30, offering convenient access and visibility for retail, restaurant, or medical use.

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    Medical Office Building on 4 Acres
    Medical Office Building on 4 Acres

    1 Professional Drive, Alton, IL 62002

    $4,000,000
    64,800 sqft 4.33 AC lot

    Brick and glass two-story medical office includes a lower level with lobby, conference room, and elevator service.

    View details
    Commercial Land Zoned CO
    Commercial Land Zoned CO

    Rush Creek Parkway, Liberty, MO 64068

    $895,000
    8.37 AC lot

    8.37-acre parcel near I-35 with CO zoning, suitable for office, medical, or other commercial development.

    View details
    Commercial Lot in Prime Location
    Commercial Lot in Prime Location

    Main Street, Peculiar, MO 64078

    $321,037
    1.18 AC lot

    1.18 acre commercial lot in Peculiar, Missouri.

    View details

    Off-Market Properties in Columbia, MO

    Consider similar Off-Market properties in Columbia, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2703 Clark Ln
    MEDICAL BUILDING

    2703 Clark Ln, Columbia, MO 65202-2432

    $525,000
    Estimated value
    15,186 sqft 8.93 AC lot
    View details
    500 Keene St Ste, Unit 303
    MEDICAL BUILDING

    500 Keene St Ste, Columbia, MO 65201-8104

    Unit 303
    Value Estimation by Request
    3,532 sqft
    View details
    105 Keene St
    MEDICAL BUILDING

    105 Keene St, Columbia, MO 65201-8377

    $1,320,000
    Estimated value
    35,165 sqft 4.13 AC lot
    View details
    401 Keene St
    MEDICAL BUILDING

    401 Keene St, Columbia, MO 65201-6625

    $975,000
    Estimated value
    23,286 sqft 2.15 AC lot
    View details
    210 Portland St
    MEDICAL BUILDING

    210 Portland St, Columbia, MO 65201-8374

    Value Estimation by Request
    4,056 sqft
    View details
    100 Keene St
    MEDICAL BUILDING

    100 Keene St, Columbia, MO 65201-6603

    Value Estimation by Request
    1,812 sqft 0.31 AC lot
    View details
    9 Ww N Blvd
    MEDICAL BUILDING

    9 Ww N Blvd, Columbia, MO 65203-2657

    Value Estimation by Request
    5,124 sqft 0.38 AC lot
    View details
    402 Keene St
    MEDICAL BUILDING

    402 Keene St, Columbia, MO 65201-8369

    $2,765,000
    Estimated value
    70,783 sqft 5.07 AC lot
    View details
    1627 Towne Dr
    MEDICAL BUILDING

    1627 Towne Dr, Columbia, MO 65202-2339

    Value Estimation by Request
    1,365 sqft 0.30 AC lot
    View details
    1705 Stadium Blvd
    MEDICAL BUILDING

    1705 Stadium Blvd, Columbia, MO 65202-1305

    Value Estimation by Request
    4,128 sqft 0.45 AC lot
    View details
    1605 Broadway
    MEDICAL BUILDING

    1605 Broadway, Columbia, MO 65201-8023

    $2,875,000
    Estimated value
    67,188 sqft 2.98 AC lot
    View details
    1601 Broadway
    MEDICAL BUILDING

    1601 Broadway, Columbia, MO 65201-8020

    $2,390,000
    Estimated value
    56,800 sqft 4.52 AC lot
    View details
    601 Nifong Blvd
    MEDICAL BUILDING

    601 Nifong Blvd, Columbia, MO 65203-6804

    Value Estimation by Request
    2,997 sqft
    View details
    6080 Bass Ln
    MEDICAL BUILDING

    6080 Bass Ln, Columbia, MO 65201-9735

    Value Estimation by Request
    6,860 sqft 20.00 AC lot
    View details
    3501 Berrywood Dr
    MEDICAL BUILDING

    3501 Berrywood Dr, Columbia, MO 65201-6584

    $1,475,000
    Estimated value
    22,611 sqft 4.81 AC lot
    View details
    811 Keene St
    MEDICAL BUILDING

    811 Keene St, Columbia, MO 65201-6634

    Value Estimation by Request
    4,889 sqft 1.06 AC lot
    View details
    500 Keene St Ste, Unit 402
    MEDICAL BUILDING

    500 Keene St Ste, Columbia, MO 65201-8104

    Unit 402
    Value Estimation by Request
    3,544 sqft
    View details
    601 Nifong Blvd
    MEDICAL BUILDING

    601 Nifong Blvd, Columbia, MO 65203-6804

    Value Estimation by Request
    2,564 sqft
    View details
    500 Keene St Ste, Unit 207
    MEDICAL BUILDING

    500 Keene St Ste, Columbia, MO 65201-8104

    Unit 207
    Value Estimation by Request
    3,761 sqft
    View details
    500 Keene St Ste, Unit 102
    MEDICAL BUILDING

    500 Keene St Ste, Columbia, MO 65201-8104

    Unit 102
    Value Estimation by Request
    2,933 sqft
    View details
    500 Keene St Ste, Unit 202
    MEDICAL BUILDING

    500 Keene St Ste, Columbia, MO 65201-8104

    Unit 202
    Value Estimation by Request
    1,195 sqft
    View details

    Columbia, MO Medical Office Space Market Trends and Statistics

    Explore 72 medical office space for sale in Columbia, MO, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 17,537 square feet of properties for sale, with an estimated market value of $4,292,885.

    Sale prices for medical spaces in Columbia, MO start at $1,792,885, averaging $2,146,442, and reaching up to $2,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 9
    Medical Office Space 5
    Office buildings 2
    Coworking space 1

    Demographics Overview

    Population 157K
    Population Growth (5Y) +3.8%
    Median Household Income $66,332
    College Educated 32.8%

    High-Yield Neighborhoods for Investment

    Identify Columbia submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    65201 $1.8M
    65203 $2.2M

    Taxes & Financing

    Average Loan-to-Value 65.0%

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