Independence, MO
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price Range / $
    $
    $
    Size
    Property Size / SF

    Independence, MO Medical Office Space for Sale

    Notify Me
    List
    Map
    Independence Office Building For Sale
    $3,100,000
    1.60 Acres

    Independence Office Building For Sale

    20101 E JACKSON Drive, Independence, MO 64057

    Office building with freeway visibility and strong retail anchors.

    • Freeway visibility from I‑70.
    • Significant existing tenant income from medical service tenants through 2027 & 2028.
    • Large vacant space (9,106 sf) available for owner occupancy or re‑tenanting.
    • Recent major capital improvements: New HVAC (2020), slate roof (2022), hot water heaters (2022), resurfaced parking lot (2022).
    • Strategic location near major retailers and the Independence Events Center.
    Updated: Mar 13
    View details
    Downtown Independence Commercial Building
    $1,150,000
    0.30 Acres

    Downtown Independence Commercial Building

    120 S Liberty Street, Independence, MO 64050

    Well-maintained commercial building in Downtown Independence suitable for various uses.

    • Prime location in the heart of Downtown Independence with excellent visibility and accessibility.
    • Well‑maintained commercial building suitable for a variety of uses.
    • Newer roof (2 years old).
    • Relatively new HVAC system (5 years old).
    • Parking Lot included.
    Updated: Sep 25, 2025
    View details
    SINGLE_FAMILY - Independence, MO
    $730,000
    0.77 Acres

    SINGLE_FAMILY - Independence, MO

    Retail space · 0.77 Acres

    4541 S Noland Road, Independence, MO 64055
    View details
    Independence Commercial Building For Sale
    $365,000
    0.28 Acres

    Independence Commercial Building For Sale

    3,456 SF commercial building in high-traffic area.

    13717 E 39th Street, Independence, MO 64055
    View details
    Medical Suites Near Centerpoint Medical
    Contact for pricing
    200,000 SF

    Medical Suites Near Centerpoint Medical

    Divisible medical suites with hospital access and ample parking.

    19550 E 39th Street, Independence, MO 64057
    View details
    Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 5 Active listings in Independence, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 6 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Medical/Office Space Available
    $525,000
    4,000 SF

    Versatile Medical/Office Space Available

    Adaptable space suitable for medical or general office use.

    1900 NW Copper Oaks Circle, Blue Springs, MO 64015
    View details
    Medical/Office Space For Rent
    $945,000
    6,802 SF

    Medical/Office Space For Rent

    Available space suitable for medical or office tenants.

    2025 Swift Ave, Kansas City, MO
    View details
    Blue Springs Commercial Flex Space
    $525,000
    0.08 Acres

    Blue Springs Commercial Flex Space

    Commercial space with flexibility, suitable for medical or office use.

    1900 NW Copper Oaks Circle, Blue Springs, MO 64015
    View details
    Medical Office Building For Sale
    Contact for pricing
    65,400 SF

    Medical Office Building For Sale

    35,400 SF medical office building with spaces available.

    373 W 101st Ter, Kansas City, MO 64114
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Lot in Prime Location
    $321,037
    1.18 Acres

    Commercial Lot in Prime Location

    1.18 acre commercial lot in Peculiar, Missouri.

    Main Street, Peculiar, MO 64078
    View details
    Commercial Lot in Peculiar, MO
    $282,704
    1.34 Acres

    Commercial Lot in Peculiar, MO

    Prime 1.34-acre commercial lot in Peculiar, Missouri.

    Main Street lot: 1, Peculiar, MO 64078
    View details
    Peculiar, MO Commercial Lot
    $282,704
    1.34 Acres

    Peculiar, MO Commercial Lot

    Prime 1.34 acre commercial lot in Peculiar, Missouri.

    Main Street lot: 1, Peculiar, MO 64078
    View details
    Topeka Commercial Corner Lot
    $225,000

    Topeka Commercial Corner Lot

    Prime commercial lot with high visibility and traffic in Topeka.

    S Kansas AVE, Topeka, KS 66612
    View details

    Off-Market Properties in Independence, MO

    Consider similar Off-Market properties in Independence, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    Independence, MO 64050

    Independence, MO 64050

    MEDICAL BUILDING • 0.18 Acres
    Value Estimation by Request
    Independence, MO 64050
    View details
    4429 Riv Blvd Ste D

    4429 Riv Blvd Ste D

    MEDICAL BUILDING • 1,975 SF
    Value Estimation by Request
    4429 Riv Blvd Ste D, Independence, MO 64055-4659
    View details
    1800 Swope Dr

    1800 Swope Dr

    MEDICAL BUILDING • 62,070 SF
    Value Estimation
    $7,405,000
    1800 Swope Dr, Independence, MO 64057-1084
    View details
    18777 39Th St

    18777 39Th St

    Medical Office Space • 150,816 SF
    Value Estimation by Request
    18777 39Th St, Independence, MO 64057
    View details
    4429 Riv Blvd Ste A

    4429 Riv Blvd Ste A

    MEDICAL BUILDING • 2,264 SF
    Value Estimation by Request
    4429 Riv Blvd Ste A, Independence, MO 64055-4659
    View details
    11605 23rd S St

    11605 23rd S St

    MEDICAL BUILDING • 1,733 SF
    Value Estimation by Request
    11605 23rd S St, Independence, MO 64050-4201
    View details

    Independence, MO Medical Office Space Investment Opportunities Market Analysis

    Explore 11 medical office space for sale in Independence, MO, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 200,000 square feet of properties for sale, with an estimated market value of $5,345,000.

    Sale prices for medical spaces in Independence, MO start at $0.00, averaging $1,069,000, and reaching up to $3,100,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map