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St Joseph, MO Medical Office Space for Sale

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Office Building with Multiple Offices
Updated: Jul 2
Office Building with Multiple Offices

20994 State Route K, St Joseph, MO 64505

$1,450,000
3.27 AC lot
Currently configured as a full‑service veterinary clinic
Multiple offices plus support, utility, and storage rooms
Rear suite includes a large multipurpose office and attached private office
Spacious lobby and reception area with two main entrances
Large paved parking lot
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Medical Office Building with Expansion Land
Updated: Dec 27, 2025
Medical Office Building with Expansion Land

3904 Beck Road, St Joseph, MO 64506

$2,100,000
2.51 AC lot
2.51‑acre medical office site in St Joseph, MO
10,012 SF main level with approximately 1,974 SF available for lease
Occupied by a dental office, orthodontist, and oral surgeon
Lower level includes finished, partially finished, storage, and utility areas
New roof installed in November 2023
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Medical Center with Highway Location
Medical Center with Highway Location

3111 N Belt Highway, St Joseph, MO 64506

$399,000
0.70 AC lot

Veterinary clinic improvements occupy a C-3-zoned parcel with on-site parking and water available.

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Medical Office Building with Lobby
Medical Office Building with Lobby

20994 State Route K N/A, St Joseph, MO 64505

$1,450,000
10,288 sqft 3.20 AC lot

Flexible commercial layout includes multiple offices, support rooms, and a dedicated rear suite for administrative or specialized functions.

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Medical Office Owner-User Opportunity
Medical Office Owner-User Opportunity

2111 N Woodbine Rd, Saint Joseph, MO

Contact for pricing
9,000 sqft 2.30 AC lot

Medicare approved ambulatory surgery center ideal for medical office.

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Medical Office Suite with 10 Rooms
Medical Office Suite with 10 Rooms

3919 Messanie St, Saint Joseph, MO 64506

$750,000

Previously built for medical use, the suite includes 10 private rooms, wet and dry systems, and dedicated parking.

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Single-Story Medical Office Campus
Single-Story Medical Office Campus

5506 Corporate Dr, Saint Joseph, MO 64507

Contact for pricing

Fully occupied two-building property serving medical office users in St. Joseph.

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Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 7 Active listings in St Joseph, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Move-In-Ready Office Suite
Move-In-Ready Office Suite

4119 Northwest Barry Road, Kansas City, MO 64154

Contact for pricing
4,600 sqft

Fully built-out suite with an open, light-filled layout, private rooms, and a premium reception area.

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Spira Care Medical Office Property
Spira Care Medical Office Property

8765 N Ambassador Dr, Kansas City, MO 64154

Contact for pricing
11,950 sqft 2.30 AC lot

Single-tenant medical office in high-traffic retail corridor.

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North Tower Office Building
North Tower Office Building

1515 West Truman Road, Independence, MO 64050

Contact for pricing
144,449 sqft

Former hospital-affiliated office property that has been largely vacant since 2010.

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Office Building with Newer Roof
Office Building with Newer Roof

120 S Liberty Street, Independence, MO 64050

$1,150,000
0.30 AC lot

C-2 zoning, an on-site parking lot, and a downtown setting support professional and community-oriented uses.

View details

St Joseph, MO Medical Office Space Market Trends and Statistics

Explore 7 medical office space for sale in St Joseph, MO, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 19,288 square feet of properties for sale, with an estimated market value of $6,149,000.

Sale prices for medical spaces in St Joseph, MO start at $399,000, averaging $1,229,800, and reaching up to $2,100,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 40
Office buildings 19
Medical Office Space 9

Demographics Overview

Population 83K
Population Growth (5Y) -4.5%
Median Household Income $58,931
College Educated 28.8%

High-Yield Neighborhoods for Investment

Identify St Joseph submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
Saint Joseph - 64506 $1.2M
Saint Joseph - 64505 $1.5M

Listings Trend

New vs delisted commercial listings in Buchanan County

New Delisted

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