Medical Premises

Saint Joseph, MO Medical Office Space for Sale

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6 properties
Medical Office Building
Updated: Jul 2
Medical Office Building

20994 State Route K, St Joseph, MO 64505

$1,450,000
3.27 AC lot
10,288‑square‑foot medical office building
Currently configured for a full‑service veterinary clinic
Two main entrances with lobby and reception area
Numerous offices, support rooms, utility rooms, and storage areas
Rear suite with multipurpose office and attached additional office
View details
Medical Office Building with Expansion Land
Updated: Dec 27, 2025
Medical Office Building with Expansion Land

3904 Beck Road, St Joseph, MO 64506

$2,100,000
2.51 AC lot
2.51‑acre medical office site in St Joseph, MO
10,012 SF main level with approximately 1,974 SF available for lease
Occupied by a dental office, orthodontist, and oral surgeon
Lower level includes finished, partially finished, storage, and utility areas
New roof installed in November 2023
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Medical Center on Large Lot
Medical Center on Large Lot

3111 N Belt Highway, St Joseph, MO 64506

$399,000
0.70 AC lot

Veterinary clinic building with parking and C-3 zoning.

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See what stands out in Buchanan County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

Cap Rate available after sign in
NOI available after sign in
Local Demand available after sign in
Medical Office Building with Lobby
Medical Office Building with Lobby

20994 State Route K N/A, St Joseph, MO 64505

$1,450,000
10,288 sqft 3.20 AC lot

Flexible commercial layout includes multiple offices, support rooms, and a dedicated rear suite for administrative or specialized functions.

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Medical Office Owner-User Opportunity
Medical Office Owner-User Opportunity

2111 N Woodbine Rd, Saint Joseph, MO

Contact for pricing
9,000 sqft 2.30 AC lot

Medicare approved ambulatory surgery center ideal for medical office.

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Medical Office Suite with 10 Rooms
Medical Office Suite with 10 Rooms

3919 Messanie St, St Joseph, MO 64506

$750,000

Previously built for medical use, the suite includes 10 private rooms, wet and dry systems, and dedicated parking.

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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
Based on your search, we've compiled 34 Potential Opportunities for your consideration. Besides 6 Active listings in Saint Joseph, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 24 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Leased Medical Office Condo
Leased Medical Office Condo

Kansas City, MO 64151

Contact for pricing
3,240 sqft

Fully leased 3,240 SF medical office condo within a condominium association, offered for sale.

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Spira Care Medical Office Property
Spira Care Medical Office Property

8765 N Ambassador Dr, Kansas City, MO 64154

Contact for pricing
11,950 sqft 2.30 AC lot

Single-tenant medical office in high-traffic retail corridor.

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North Tower Office Building
North Tower Office Building

1515 West Truman Road, Independence, MO 64050

Contact for pricing
144,449 sqft

Former hospital-affiliated office property that has been largely vacant since 2010.

View details
Office Building with Newer Roof
Office Building with Newer Roof

120 S Liberty Street, Independence, MO 64050

$1,150,000
0.30 AC lot

The property is presented for office, medical, daycare, and community-oriented uses, with C-2 zoning and a parking lot.

View details

Off-Market Properties in Saint Joseph, MO

Consider similar Off-Market properties in Saint Joseph, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

103 36th St
MEDICAL BUILDING

103 36th St, Saint Joseph, MO 64506-2920

Estimated value:
$295,000
2,064 sqft
View details
3815 Beck Rd
MEDICAL BUILDING

3815 Beck Rd, Saint Joseph, MO 64506-4941

Estimated value:
$350,000
4,711 sqft 2.44 AC lot
View details
420 Woodbine Rd
MEDICAL BUILDING

420 Woodbine Rd, Saint Joseph, MO 64506-3468

Estimated value:
$305,000
2,936 sqft
View details
3105 Frederick Ave
MEDICAL BUILDING

3105 Frederick Ave, Saint Joseph, MO 64506-2960

Estimated value:
$360,000
5,546 sqft 1.17 AC lot
View details
1011 Saint Maartens Dr
MEDICAL BUILDING

1011 Saint Maartens Dr, Saint Joseph, MO 64506-2993

Estimated value:
$330,000
5,958 sqft 0.81 AC lot
View details
1351 Buchanan Ave
MEDICAL BUILDING

1351 Buchanan Ave, Saint Joseph, MO 64501

Estimated value:
$285,000
1,570 sqft
View details
1000 5th Ave
MEDICAL BUILDING

1000 5th Ave, Saint Joseph, MO 64505-2111

Estimated value:
$300,000
3,480 sqft 1.55 AC lot
View details
1005 Saint Maartens Dr
MEDICAL BUILDING

1005 Saint Maartens Dr, Saint Joseph, MO 64506-2969

Estimated value:
$615,000
4,760 sqft 0.66 AC lot
View details
3201 Ashland Ave
MEDICAL BUILDING

3201 Ashland Ave, Saint Joseph, MO 64506-1543

Estimated value:
$430,000
11,174 sqft 1.40 AC lot
View details
2011 36th St
MEDICAL BUILDING

2011 36th St, Saint Joseph, MO 64506

Estimated value:
$305,000
2,732 sqft
View details
2401 Frederick Ave
MEDICAL BUILDING

2401 Frederick Ave, Saint Joseph, MO 64506-2727

Estimated value:
$305,000
4,746 sqft
View details
3110 Karnes Rd
Medical Office Space

3110 Karnes Rd, Saint Joseph, MO 64506

Estimated value:
by Request
11,400 sqft 0.94 AC lot
View details
1009 St. Maartens Dr
Medical Office Space

1009 St. Maartens Dr, Saint Joseph, MO 64506

Estimated value:
by Request
View details
3107 Belt Hwy
Medical Office Space

3107 Belt Hwy, Saint Joseph, MO 64506

Estimated value:
by Request
View details
3110 Karnes Rd. Suite 1A St
Medical Office Space

3110 Karnes Rd. Suite 1A St, Saint Joseph, MO 64506

Estimated value:
by Request
3,592 sqft
View details
802 Jules St
MEDICAL BUILDING

802 Jules St, Saint Joseph, MO 64501-1944

Estimated value:
$420,000
10,527 sqft 0.39 AC lot
View details
3109 Frederick Ave
MEDICAL BUILDING

3109 Frederick Ave, Saint Joseph, MO 64506-2959

Estimated value:
$340,000
4,620 sqft
View details
3107 Frederick Ave
MEDICAL BUILDING

3107 Frederick Ave, Saint Joseph, MO 64506-2956

Estimated value:
$435,000
9,836 sqft 1.01 AC lot
View details

Saint Joseph, MO Medical Office Space Market Trends and Statistics

Explore 30 medical office space for sale in Saint Joseph, MO, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 19,288 square feet of properties for sale, with an estimated market value of $6,149,000.

Sale prices for medical spaces in Saint Joseph, MO start at $399,000, averaging $1,229,800, and reaching up to $2,100,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 35
Office buildings 19
Medical Office Space 12

Demographics Overview

Population 83K
Population Growth (5Y) -4.5%
Median Household Income $58,931
College Educated 21.6%

High-Yield Neighborhoods for Investment

Identify Saint Joseph submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
64506 $750K

Taxes & Financing

Tax Rate (average for all types) 7.45%
Property Tax per SF $89.81 per SF
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Buchanan County

New Delisted

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