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    Mission, TX Medical Office Space for Lease

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    La Joya, TX Palmview, TX Palmhurst, TX Mcallen, TX Alton, TX Hidalgo, TX Penitas, TX Pharr, TX
    8 properties
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    Medical Office Suite with Balcony
    Updated: Mar 24
    Medical Office Suite with Balcony

    1112 Griffin Parkway, Mission, TX 78572

    $2,750/Mo
    1,350 sqft
    Prime location in the Advanced Medical Arts Center, enhancing professional image and client perception.
    Fully finished and ready‑to‑use Suite 1112‑D, facilitating immediate occupancy and operations.
    Dual access from Bryan Rd & Griffin Parkway, ensuring convenient client access and ample parking.
    Stunning aesthetics, including a gorgeous courtyard, fountain gardens, and golf course views.
    Scalable space, providing the flexibility to expand as your business grows.
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    Flexible Retail, Office & Medical Suites
    Updated: Apr 30
    Flexible Retail, Office & Medical Suites

    2205 N Bryan Road Unit 1, Mission, TX 78572

    $18 SF/Yr
    1,940 sqft
    Newly developed retail strip center in Mission, Texas built in 2026
    11,640 SF total retail strip center with 6 units at approximately 1,940 SF each
    Over 40 parking spaces to support customer access
    Flexible layouts suitable for retail, office, or medical use
    Modern floor plans throughout the center
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    Retail Strip Center with Flexible Layouts
    Retail Strip Center with Flexible Layouts

    5-2205 N Bryan Rd, Mission, TX 78572

    $3,744/Mo
    1,940 sqft

    Newly developed strip center with six sizable units and ample parking for retail, office, or medical use.

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    Medical Office Suite with Covered Patio
    Medical Office Suite with Covered Patio

    12-909 Business Park Dr, Mission, TX 78572

    $11,188/Mo
    6,067 sqft

    Medical suite features an open area, offices, restrooms, kitchen, storage, and covered patio for day-to-day patient care.

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    Retail Strip Center with Flexible Suites
    Retail Strip Center with Flexible Suites

    2205 N Bryan Road # 5, Mission, TX 78572

    $23.16 SF/Yr
    11,640 sqft

    Newly developed strip center with six suites, modern floor plans, and over 40 parking spaces suitable for retail, office, or medical.

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    Corner Retail and Medical Suite
    Corner Retail and Medical Suite

    108-4322 N Conway Ave, Mission, TX 78572

    $1,523/Mo
    1,108 sqft

    Retail/medical suite within a shopping center anchored by Walmart, with adjacent space available for expansion.

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    Medical Office Space Near Hospital
    Medical Office Space Near Hospital

    900 Plaza Drive # A #1-A, Mission, TX 78572

    $22.08 SF/Yr
    4,027 sqft

    Multi-tenant medical office building near Mission Regional Medical Center.

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    Strip Center with Medical Office
    Strip Center with Medical Office

    3401 W Mile 5 Rd, Mission, TX 78574

    $15 SF/Yr
    2,500 sqft

    Three-unit strip center ideal for medical, retail, or office.

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    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 8 Active listings in Mission, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    New Construction Strip Center
    New Construction Strip Center

    324 N Alton Boulevard, Alton, TX 78573

    $2,583/Mo
    15,175 sqft

    New commercial strip center with flexible office, retail, or medical space and ample parking at a corner location.

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    New Construction Retail Strip Center
    New Construction Retail Strip Center

    324 N Alton Boulevard, Alton, TX 78573

    $2,513/Mo
    15,175 sqft

    New construction retail strip center on a high-visibility corner with ample parking and flexible space options.

    View details
    Remodeled Corner Office Suite
    Remodeled Corner Office Suite

    733 N Ware Rd, Mcallen, TX 78501

    $5,000/Mo
    3,000 sqft

    Fully remodeled corner office unit with two entrances, reception, 12 private offices, conference room, kitchen area, and two bathrooms.

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    Remodeled Move-In Ready Medical Office
    Remodeled Move-In Ready Medical Office

    713 Savannah Ave, Mcallen, TX 78503

    $2,800/Mo
    1,820 sqft

    Fully remodeled medical office includes an entry lobby, exam rooms, and a secure records room.

    View details

    Similar Spaces for Sale in Mission, TX

    Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

    Medical Office Building with Parking
    Medical Office Building with Parking

    1022 E Griffin Parkway, Mission, TX 78572

    $600,000
    2,400 sqft 0.17 AC lot

    Medical office building with a lobby, multiple work stations/exam rooms, and several interior offices, plus ample parking.

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    Full-Service Restaurant Building
    Full-Service Restaurant Building

    2100 E Griffin Parkway, Mission, TX 78572

    $750,000
    4,620 sqft

    Restaurant building with multiple dining areas, private rooms, and a commercial kitchen, suited for medical or office conversion.

    View details
    Medical Office Building
    Medical Office Building

    104-b-1022 E Griffin Pkwy, Mission, TX 78572

    $600,000
    2,400 sqft

    Medical office building with a reception lobby, exam/work stations, and both full and half bathrooms.

    View details
    Retail Shopping Center Opportunity
    Retail Shopping Center Opportunity

    2500 North Conway Avenue, Mission, TX 78574

    $2,653,627
    12,120 sqft

    Located on North Conway Avenue, with in-place rents below market and an HEB anchor nearby supporting steady demand.

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    Medical Office Building with Lobby
    Medical Office Building with Lobby

    1022 E Griffin Parkway # B ##104 B, Mission, TX 78572

    $650,000
    2,400 sqft

    Medical office space with reception, multiple exam or work rooms, and ample parking in Mission.

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    Freestanding Medical Office Building
    Freestanding Medical Office Building

    10400 N 103rd Street, Mission, TX 78573

    Contact for pricing
    5,280 sqft 0.34 AC lot

    Freestanding two-unit medical/office building with ample customer parking and corner exposure.

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    Professional Office Building
    Professional Office Building

    600 E Griffin Parkway, Mission, TX 78572

    Contact for pricing
    7,429 sqft

    Prestige Plaza is a 7,429-sf professional office building with current mixed occupancy, including a dental tenant.

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    Restaurant with Medical Office Flex Space
    Restaurant with Medical Office Flex Space

    6912 N La Homa Road, Mission, TX 78574

    Contact for pricing

    Former restaurant space includes an additional area that can be used as a medical office, with ample customer parking.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land for Long-Term Lease
    Commercial Land for Long-Term Lease

    5538 E Paisano Drive, El Paso, TX 79905

    $5,950/Mo

    Lease a C4-zoned lot with easy interstate access, suited for a range of business and professional uses.

    View details
    Office Development Land For Lease
    Office Development Land For Lease

    1323 Strawfloor Drive, Jonesboro, AR 72401

    Contact for pricing
    4,000 sqft

    2.43 acres for office development with build-to-suit opportunity.

    View details
    Corner Lot on Highway 72
    Corner Lot on Highway 72

    30472 Highway 72, Madison, AL 35756

    $5,000/Mo
    1,875 sqft

    1.7 acre corner lot zoned for commercial, medical, residential.

    View details
    Prime Commercial Lot For Rent
    Prime Commercial Lot For Rent

    Tift Avenue N, Tifton, GA 31794

    $7,500/Mo

    0.66 acre commercial lot with high visibility.

    View details

    Mission, TX Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Mission, TX with 8 listings featured on our commercial real estate exchange. The current inventory includes 30,572 square feet of properties with an estimated lease value of $164.46 SF/Yr.

    Estimated lease rates for Medical Office Space in Mission, TX begin at $15 SF/Yr, with an average of $20.56 SF/Yr and extend to $24.44 SF/Yr.
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    Most Searched ZIP Codes in Mission, TX

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    • 78574

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